abnormal trophectoderm morphology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any structural anomaly outermost layer of cells in the blastodermic vesicle, which will develop into the trophoblast layer and then contact the endometrium and take part in establishing the embryo's means of nutrition (Mammalian Phenotype Ontology, MP_0005028)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0005028
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Genes

106 gene mutations causing the abnormal trophectoderm morphology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ALKBH1 alkB, alkylation repair homolog 1 (E. coli)
ARNT aryl hydrocarbon receptor nuclear translocator
ATAD3A ATPase family, AAA domain containing 3A
AURKB aurora kinase B
BIRC5 baculoviral IAP repeat containing 5
BMP5 bone morphogenetic protein 5
BPTF bromodomain PHD finger transcription factor
BRCA1 breast cancer 1, early onset
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDX2 caudal type homeobox 2
CENPA centromere protein A
CHM choroideremia (Rab escort protein 1)
COPS2 COP9 signalosome subunit 2
CR1L complement component (3b/4b) receptor 1-like
CSNK2B casein kinase 2, beta polypeptide
CTCF CCCTC-binding factor (zinc finger protein)
CUL3 cullin 3
CUL7 cullin 7
CXXC1 CXXC finger protein 1
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9
DNM1L dynamin 1-like
DNMT3L DNA (cytosine-5-)-methyltransferase 3-like
EGFR epidermal growth factor receptor
EGLN1 egl-9 family hypoxia-inducible factor 1
EHMT2 euchromatic histone-lysine N-methyltransferase 2
ELAVL1 ELAV like RNA binding protein 1
ELF5 E74-like factor 5 (ets domain transcription factor)
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EOMES eomesodermin
EPCAM epithelial cell adhesion molecule
ERF Ets2 repressor factor
ESRRB estrogen-related receptor beta
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
EVX1 even-skipped homeobox 1
FBXL5 F-box and leucine-rich repeat protein 5
FEN1 flap structure-specific endonuclease 1
FGFR2 fibroblast growth factor receptor 2
FRS2 fibroblast growth factor receptor substrate 2
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GAB1 GRB2-associated binding protein 1
GMNN geminin, DNA replication inhibitor
GNL3 guanine nucleotide binding protein-like 3 (nucleolar)
GNPNAT1 glucosamine-phosphate N-acetyltransferase 1
HAND1 heart and neural crest derivatives expressed 1
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
IL11RA interleukin 11 receptor, alpha
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITGB7 integrin, beta 7
KDM6A lysine (K)-specific demethylase 6A
KLF5 Kruppel-like factor 5 (intestinal)
KRT8 keratin 8, type II
LAMA1 laminin, alpha 1
LAMB1 laminin, beta 1
MAP2K1 mitogen-activated protein kinase kinase 1
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MDFI MyoD family inhibitor
MED1 mediator complex subunit 1
MET MET proto-oncogene, receptor tyrosine kinase
MFN2 mitofusin 2
MTOR mechanistic target of rapamycin (serine/threonine kinase)
N6AMT1 N-6 adenine-specific DNA methyltransferase 1 (putative)
NBN nibrin
NCOA6 nuclear receptor coactivator 6
NDUFA13 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
NF2 neurofibromin 2 (merlin)
NODAL nodal growth differentiation factor
PBRM1 polybromo 1
PIKFYVE phosphoinositide kinase, FYVE finger containing
PLAC1 placenta-specific 1
PMM2 phosphomannomutase 2
PNPLA6 patatin-like phospholipase domain containing 6
POU2F1 POU class 2 homeobox 1
PPARG peroxisome proliferator-activated receptor gamma
PPP1R8 protein phosphatase 1, regulatory subunit 8
PRDM1 PR domain containing 1, with ZNF domain
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RANGAP1 Ran GTPase activating protein 1
RECQL4 RecQ protein-like 4
RPTOR regulatory associated protein of MTOR, complex 1
RTEL1 regulator of telomere elongation helicase 1
RYBP RING1 and YY1 binding protein
SALL4 spalt-like transcription factor 4
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2
SMAD2 SMAD family member 2
SMAD4 SMAD family member 4
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1
SNX13 sorting nexin 13
SOCS3 suppressor of cytokine signaling 3
SOX2 SRY (sex determining region Y)-box 2
SPINT1 serine peptidase inhibitor, Kunitz type 1
SSB Sjogren syndrome antigen B (autoantigen La)
T T, brachyury homolog (mouse)
TEAD4 TEA domain family member 4
TERF1 telomeric repeat binding factor (NIMA-interacting) 1
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TFDP1 transcription factor Dp-1
THBD thrombomodulin
TRRAP transformation/transcription domain-associated protein
TSIX TSIX transcript, XIST antisense RNA
TTPA tocopherol (alpha) transfer protein
TXNRD1 thioredoxin reductase 1
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae)
ZNF830 zinc finger protein 830
ZPR1 ZPR1 zinc finger