abnormal tricuspid valve morphology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any structural anomaly of the valve located between the right atrium and the right ventricle of the heart, and contains three cusps, the anterior cusp (infundibular cusp), the posterior cusp (marginal cusp), and the septal cusp (medial cusp), attached to the outer fibrous ring (anulus) (Mammalian Phenotype Ontology, MP_0002624)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0002624
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Genes

21 gene mutations causing the abnormal tricuspid valve morphology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ADAM17 ADAM metallopeptidase domain 17
ADAM19 ADAM metallopeptidase domain 19
CC2D2A coiled-coil and C2 domain containing 2A
CNTRL centriolin
COL18A1 collagen, type XVIII, alpha 1
HBEGF heparin-binding EGF-like growth factor
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
IDUA iduronidase, alpha-L-
IGF2R insulin-like growth factor 2 receptor
LEFTY1 left-right determination factor 1
LEFTY2 left-right determination factor 2
MEGF8 multiple EGF-like-domains 8
MMP21 matrix metallopeptidase 21
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
PAX3 paired box 3
PDLIM7 PDZ and LIM domain 7 (enigma)
RXRA retinoid X receptor, alpha
SMAD6 SMAD family member 6
TGFB2 transforming growth factor, beta 2
ZFPM2 zinc finger protein, FOG family member 2