abnormal transitional stage b cell morphology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any structural anomaly of an immature B cell of an intermediate stage between the pre-B cell stage and the mature naive stage; transitional B cells express surface immunoglobulin, and are subject to the process of B cell selection (Mammalian Phenotype Ontology, MP_0008188)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008188
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Genes

45 gene mutations causing the abnormal transitional stage b cell morphology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AKAP13 A kinase (PRKA) anchor protein 13
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ATP11C ATPase, class VI, type 11C
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BCL3 B-cell CLL/lymphoma 3
BLNK B-cell linker
BMF Bcl2 modifying factor
BTK Bruton agammaglobulinemia tyrosine kinase
CD22 CD22 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD79A CD79a molecule, immunoglobulin-associated alpha
CD79B CD79b molecule, immunoglobulin-associated beta
DLK1 delta-like 1 homolog (Drosophila)
EPS15 epidermal growth factor receptor pathway substrate 15
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
FAS Fas cell surface death receptor
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FNIP1 folliculin interacting protein 1
HAX1 HCLS1 associated protein X-1
IGHM immunoglobulin heavy constant mu
IRF8 interferon regulatory factor 8
LTA lymphotoxin alpha
LYN LYN proto-oncogene, Src family tyrosine kinase
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MTOR mechanistic target of rapamycin (serine/threonine kinase)
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NPY1R neuropeptide Y receptor Y1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PRKCD protein kinase C, delta
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPRC protein tyrosine phosphatase, receptor type, C
SH2D1A SH2 domain containing 1A
SH3BP2 SH3-domain binding protein 2
SPNS2 spinster homolog 2 (Drosophila)
SPPL2A signal peptide peptidase like 2A
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
SYK spleen tyrosine kinase
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TRAF3IP2 TRAF3 interacting protein 2
VAV1 vav 1 guanine nucleotide exchange factor
ZBTB1 zinc finger and BTB domain containing 1