abnormal tooth hard tissue morphology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any structural anomaly of the hard portion of the tooth surrounding the pulp, including the dentin, enamel and the cementum on the root (Mammalian Phenotype Ontology, MP_0003930)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0003930
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38 gene mutations causing the abnormal tooth hard tissue morphology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2
AMBN ameloblastin (enamel matrix protein)
AMELY amelogenin, Y-linked
ANKH ANKH inorganic pyrophosphate transport regulator
ANTXR1 anthrax toxin receptor 1
CHUK conserved helix-loop-helix ubiquitous kinase
CSF1 colony stimulating factor 1 (macrophage)
DLX5 distal-less homeobox 5
DMP1 dentin matrix acidic phosphoprotein 1
DSPP dentin sialophosphoprotein
EDA ectodysplasin A
EDARADD EDAR-associated death domain
ENAM enamelin
FAM20A family with sequence similarity 20, member A
FAM20C family with sequence similarity 20, member C
GJA1 gap junction protein, alpha 1, 43kDa
ITGA11 integrin, alpha 11
KLK4 kallikrein-related peptidase 4
LAMA3 laminin, alpha 3
LRP4 low density lipoprotein receptor-related protein 4
MMP20 matrix metallopeptidase 20
MSX2 msh homeobox 2
NFE2L2 nuclear factor, erythroid 2-like 2
NFIC nuclear factor I/C (CCAAT-binding transcription factor)
NOS2 nitric oxide synthase 2, inducible
OSTM1 osteopetrosis associated transmembrane protein 1
PAX9 paired box 9
POSTN periostin, osteoblast specific factor
PTCH1 patched 1
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C)
RUNX2 runt-related transcription factor 2
SLC24A4 solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
SMPD3 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
SOSTDC1 sclerostin domain containing 1
SP3 Sp3 transcription factor
SP6 Sp6 transcription factor
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
TGFB1 transforming growth factor, beta 1