abnormal thyroxine level Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any anomaly in the concentration of the major hormone derived from the thyroid gland; it normally affects cellular metabolism (Mammalian Phenotype Ontology, MP_0005469)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0005469
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Genes

46 gene mutations causing the abnormal thyroxine level phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AGRP agouti related neuropeptide
AKT1 v-akt murine thymoma viral oncogene homolog 1
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
CAND2 cullin-associated and neddylation-dissociated 2 (putative)
CRYM crystallin, mu
CTSV cathepsin V
CYBA cytochrome b-245, alpha polypeptide
DIO1 deiodinase, iodothyronine, type I
DIO2 deiodinase, iodothyronine, type II
DIO3 deiodinase, iodothyronine, type III
DUOX2 dual oxidase 2
GCNT4 glucosaminyl (N-acetyl) transferase 4, core 2
GGT1 gamma-glutamyltransferase 1
GHR growth hormone receptor
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
HPN hepsin
KLC2 kinesin light chain 2
LEPROT leptin receptor overlapping transcript
LHX3 LIM homeobox 3
MCHR1 melanin-concentrating hormone receptor 1
MED1 mediator complex subunit 1
NCOA1 nuclear receptor coactivator 1
NCOR1 nuclear receptor corepressor 1
NR1I3 nuclear receptor subfamily 1, group I, member 3
OAT ornithine aminotransferase
PAX8 paired box 8
PDYN prodynorphin
POMC proopiomelanocortin
PRLR prolactin receptor
RUNX2 runt-related transcription factor 2
SIRT1 sirtuin 1
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter)
SLCO1C1 solute carrier organic anion transporter family, member 1C1
SMPD3 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
SSFA2 sperm specific antigen 2
TG thyroglobulin
THRA thyroid hormone receptor, alpha
THRB thyroid hormone receptor, beta
TPST2 tyrosylprotein sulfotransferase 2
TRH thyrotropin-releasing hormone
TRHR thyrotropin-releasing hormone receptor
TSHR thyroid stimulating hormone receptor
TTR transthyretin
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
VGF VGF nerve growth factor inducible
WDR37 WD repeat domain 37