abnormal thromboxane level Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description anomalous concentration in the body of any of several compounds, originally derived from prostaglandin precursors in platelets, that stimulate aggregation of platelets and constriction of blood vessels (Mammalian Phenotype Ontology, MP_0009818)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0009818
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Genes

6 gene mutations causing the abnormal thromboxane level phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ALOX5 arachidonate 5-lipoxygenase
ALOX5AP arachidonate 5-lipoxygenase-activating protein
PTGIR prostaglandin I2 (prostacyclin) receptor (IP)
PTGIS prostaglandin I2 (prostacyclin) synthase
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
TBXA2R thromboxane A2 receptor