abnormal t-helper 2 cell differentiation Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description atypical production of or inability to produce the type of T-helper cell whose cytokine production promotes defense against extracellular parasites and humoral immune responses typical of allergy (Mammalian Phenotype Ontology, MP_0008092)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008092
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Genes

14 gene mutations causing the abnormal t-helper 2 cell differentiation phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
BATF basic leucine zipper transcription factor, ATF-like
BHLHE41 basic helix-loop-helix family, member e41
C3AR1 complement component 3a receptor 1
CARD11 caspase recruitment domain family, member 11
CISH cytokine inducible SH2-containing protein
ICOSLG inducible T-cell co-stimulator ligand
IL13 interleukin 13
IL17RA interleukin 17 receptor A
IL4 interleukin 4
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3
PGAP3 post-GPI attachment to proteins 3
RSAD2 radical S-adenosyl methionine domain containing 2
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
TSLP thymic stromal lymphopoietin