abnormal t-helper 1 cell differentiation Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description atypical production of or inability to produce the subset of the type of T-helper cell whose cytokine production favors cellular immune responses and delayed type hypersensitivity (Mammalian Phenotype Ontology, MP_0008088)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008088
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Genes

20 gene mutations causing the abnormal t-helper 1 cell differentiation phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
CD247 CD247 molecule
CD274 CD274 molecule
GADD45B growth arrest and DNA-damage-inducible, beta
GADD45G growth arrest and DNA-damage-inducible, gamma
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1)
IL2 interleukin 2
IL4 interleukin 4
IRF4 interferon regulatory factor 4
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPK9 mitogen-activated protein kinase 9
PCSK1 proprotein convertase subtilisin/kexin type 1
PRKCQ protein kinase C, theta
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
REL v-rel avian reticuloendotheliosis viral oncogene homolog
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SIT1 signaling threshold regulating transmembrane adaptor 1
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
TBX21 T-box 21
UNC93B1 unc-93 homolog B1 (C. elegans)