abnormal t cell clonal deletion Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description a defect in the process of removal of immature T lymphocytes that interact with self antigens during maturation (Mammalian Phenotype Ontology, MP_0005002)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0005002
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Genes

6 gene mutations causing the abnormal t cell clonal deletion phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
CD40LG CD40 ligand
FAS Fas cell surface death receptor
FYN FYN proto-oncogene, Src family tyrosine kinase
IL2RB interleukin 2 receptor, beta
IL6ST interleukin 6 signal transducer
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa