abnormal susceptibility to induced colitis Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description difference in the severity or induction threshold of colitis upon treatment of an organism with intestinal inflammation agents such as dextran sodium sulfate (DSS) (Mammalian Phenotype Ontology, MP_0013296)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0013296
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Genes

78 gene mutations causing the abnormal susceptibility to induced colitis phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ADAM17 ADAM metallopeptidase domain 17
AGR2 anterior gradient 2
ANXA1 annexin A1
APOA4 apolipoprotein A-IV
AQP3 aquaporin 3 (Gill blood group)
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
B3GNT6 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6
BTK Bruton agammaglobulinemia tyrosine kinase
CCL13 chemokine (C-C motif) ligand 13
CCR2 chemokine (C-C motif) receptor 2
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CYLD cylindromatosis (turban tumor syndrome)
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DMBT1 deleted in malignant brain tumors 1
EBI3 Epstein-Barr virus induced 3
EREG epiregulin
ERN2 endoplasmic reticulum to nucleus signaling 2
F2R coagulation factor II (thrombin) receptor
FFAR2 free fatty acid receptor 2
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type
GPR15 G protein-coupled receptor 15
ICAM1 intercellular adhesion molecule 1
IER3 immediate early response 3
IL10 interleukin 10
IL10RA interleukin 10 receptor, alpha
IL17A interleukin 17A
IL17F interleukin 17F
IL17RE interleukin 17 receptor E
IL18 interleukin 18
IL22 interleukin 22
IL23A interleukin 23, alpha subunit p19
IL33 interleukin 33
IL6 interleukin 6
IL6ST interleukin 6 signal transducer
MBTPS1 membrane-bound transcription factor peptidase, site 1
MEP1A meprin A, alpha (PABA peptide hydrolase)
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
MST1 macrophage stimulating 1
MUC2 mucin 2, oligomeric mucus/gel-forming
MYD88 myeloid differentiation primary response 88
NFE2L2 nuclear factor, erythroid 2-like 2
NFIL3 nuclear factor, interleukin 3 regulated
NFKBID nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta
NLRP12 NLR family, pyrin domain containing 12
NLRP3 NLR family, pyrin domain containing 3
NLRP6 NLR family, pyrin domain containing 6
NOD2 nucleotide-binding oligomerization domain containing 2
NOS2 nitric oxide synthase 2, inducible
NR5A2 nuclear receptor subfamily 5, group A, member 2
PGLYRP1 peptidoglycan recognition protein 1
PGLYRP2 peptidoglycan recognition protein 2
PGLYRP3 peptidoglycan recognition protein 3
PGLYRP4 peptidoglycan recognition protein 4
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PYCARD PYD and CARD domain containing
RAG1 recombination activating gene 1
RASA1 RAS p21 protein activator (GTPase activating protein) 1
RASGRP4 RAS guanyl releasing protein 4
RETNLB resistin like beta
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
TBX21 T-box 21
TFF3 trefoil factor 3 (intestinal)
TICAM1 toll-like receptor adaptor molecule 1
TIGAR TP53 induced glycolysis regulatory phosphatase
TKTL1 transketolase-like 1
TLR2 toll-like receptor 2
TLR5 toll-like receptor 5
TLR9 toll-like receptor 9
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TP53INP1 tumor protein p53 inducible nuclear protein 1
TRPV5 transient receptor potential cation channel, subfamily V, member 5
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
YIPF6 Yip1 domain family, member 6
ZNF148 zinc finger protein 148