abnormal spleen weight Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description anomaly in the average weight of the organ that functions to filter blood and to store red corpuscles and platelets (Mammalian Phenotype Ontology, MP_0004951)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0004951
Similar Terms
Downloads & Tools

Genes

159 gene mutations causing the abnormal spleen weight phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ADD2 adducin 2 (beta)
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2
AHR aryl hydrocarbon receptor
AIF1 allograft inflammatory factor 1
AIRE autoimmune regulator
AKAP13 A kinase (PRKA) anchor protein 13
ALOX15 arachidonate 15-lipoxygenase
ANK1 ankyrin 1, erythrocytic
APOE apolipoprotein E
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ASXL1 additional sex combs like transcriptional regulator 1
ATR ATR serine/threonine kinase
BAG3 BCL2-associated athanogene 3
BCL2 B-cell CLL/lymphoma 2
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BCO2 beta-carotene oxygenase 2
BOK BCL2-related ovarian killer
BRAF B-Raf proto-oncogene, serine/threonine kinase
C4A complement component 4A (Rodgers blood group)
CCNE1 cyclin E1
CD72 CD72 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CIDEB cell death-inducing DFFA-like effector b
COL10A1 collagen, type X, alpha 1
CORO1A coronin, actin binding protein, 1A
CSF1 colony stimulating factor 1 (macrophage)
CSF1R colony stimulating factor 1 receptor
CTSG cathepsin G
CXCR2 chemokine (C-X-C motif) receptor 2
CXCR4 chemokine (C-X-C motif) receptor 4
CYCS cytochrome c, somatic
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DBNL drebrin-like
DCC DCC netrin 1 receptor
DCK deoxycytidine kinase
DEDD death effector domain containing
DIAPH1 diaphanous-related formin 1
DIDO1 death inducer-obliterator 1
DRD2 dopamine receptor D2
DUSP6 dual specificity phosphatase 6
E2F2 E2F transcription factor 2
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EGLN1 egl-9 family hypoxia-inducible factor 1
EGR1 early growth response 1
ELMOD1 ELMO/CED-12 domain containing 1
EPAS1 endothelial PAS domain protein 1
EPB42 erythrocyte membrane protein band 4.2
EPGN epithelial mitogen
EPO erythropoietin
EPOR erythropoietin receptor
ERCC5 excision repair cross-complementation group 5
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FECH ferrochelatase
FGF10 fibroblast growth factor 10
FOXP3 forkhead box P3
GATA1 GATA binding protein 1 (globin transcription factor 1)
GBA glucosidase, beta, acid
GHR growth hormone receptor
GLMP glycosylated lysosomal membrane protein
GPC3 glypican 3
GPI glucose-6-phosphate isomerase
GRB14 growth factor receptor-bound protein 14
GSTK1 glutathione S-transferase kappa 1
GSTZ1 glutathione S-transferase zeta 1
HCST hematopoietic cell signal transducer
HK1 hexokinase 1
HOXA9 homeobox A9
HSH2D hematopoietic SH2 domain containing
IGHM immunoglobulin heavy constant mu
IL10RB interleukin 10 receptor, beta
IL7 interleukin 7
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
ITGAD integrin, alpha D
KAT6A K(lysine) acetyltransferase 6A
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KDM8 lysine (K)-specific demethylase 8
KISS1R KISS1 receptor
KLF1 Kruppel-like factor 1 (erythroid)
KLF3 Kruppel-like factor 3 (basic)
KLHL6 kelch-like family member 6
LDHA lactate dehydrogenase A
LGMN legumain
LIG4 ligase IV, DNA, ATP-dependent
LIPA lipase A, lysosomal acid, cholesterol esterase
LTA lymphotoxin alpha
LYN LYN proto-oncogene, Src family tyrosine kinase
MARK2 MAP/microtubule affinity-regulating kinase 2
MARVELD2 MARVEL domain containing 2
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MFGE8 milk fat globule-EGF factor 8 protein
MIR144 microRNA 144
MIR451A microRNA 451a
MST1R macrophage stimulating 1 receptor
MXRA7 matrix-remodelling associated 7
MYC v-myc avian myelocytomatosis viral oncogene homolog
NDFIP1 Nedd4 family interacting protein 1
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NKX2-3 NK2 homeobox 3
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NR1H4 nuclear receptor subfamily 1, group H, member 4
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
OCA2 oculocutaneous albinism II
PAPPA2 pappalysin 2
PFKM phosphofructokinase, muscle
PGM3 phosphoglucomutase 3
PHC1 polyhomeotic homolog 1 (Drosophila)
PLA2G15 phospholipase A2, group XV
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PRDX1 peroxiredoxin 1
PRDX2 peroxiredoxin 2
PREP prolyl endopeptidase
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PSAP prosaposin
PTP4A2 protein tyrosine phosphatase type IVA, member 2
PTTG1 pituitary tumor-transforming 1
PURA purine-rich element binding protein A
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RC3H1 ring finger and CCCH-type domains 1
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RRAS2 related RAS viral (r-ras) oncogene homolog 2
SELENBP1 selenium binding protein 1
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SPI1 Spi-1 proto-oncogene
SPIC Spi-C transcription factor (Spi-1/PU.1 related)
SPTA1 spectrin, alpha, erythrocytic 1
STEAP3 STEAP family member 3, metalloreductase
TAL1 T-cell acute lymphocytic leukemia 1
TBC1D4 TBC1 domain family, member 4
TBK1 TANK-binding kinase 1
TERT telomerase reverse transcriptase
TLR4 toll-like receptor 4
TLR8 toll-like receptor 8
TMPRSS6 transmembrane protease, serine 6
TNF tumor necrosis factor
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TNIP1 TNFAIP3 interacting protein 1
TP53 tumor protein p53
TPI1 triosephosphate isomerase 1
TRAF3IP2 TRAF3 interacting protein 2
TTC7A tetratricopeptide repeat domain 7A
ULK1 unc-51 like autophagy activating kinase 1
UNC93B1 unc-93 homolog B1 (C. elegans)
USP21 ubiquitin specific peptidase 21
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
WWOX WW domain containing oxidoreductase
ZFPM1 zinc finger protein, FOG family member 1