abnormal spleen morphology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any structural anomaly of the organ that functions to filter blood and to store red corpuscles and platelets (Mammalian Phenotype Ontology, MP_0000689)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0000689
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Genes

675 gene mutations causing the abnormal spleen morphology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCC10 ATP-binding cassette, sub-family C (CFTR/MRP), member 10
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACKR3 atypical chemokine receptor 3
ACKR4 atypical chemokine receptor 4
ACVR2B activin A receptor, type IIB
ADD2 adducin 2 (beta)
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2
AHR aryl hydrocarbon receptor
AHSP alpha hemoglobin stabilizing protein
AIF1 allograft inflammatory factor 1
AIRE autoimmune regulator
AKAP12 A kinase (PRKA) anchor protein 12
AKAP13 A kinase (PRKA) anchor protein 13
ALOX15 arachidonate 15-lipoxygenase
ALOX5 arachidonate 5-lipoxygenase
ALPL alkaline phosphatase, liver/bone/kidney
AMER1 APC membrane recruitment protein 1
ANK1 ankyrin 1, erythrocytic
APC adenomatous polyposis coli
APCS amyloid P component, serum
APOE apolipoprotein E
ARHGAP1 Rho GTPase activating protein 1
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ARID4A AT rich interactive domain 4A (RBP1-like)
ARID5B AT rich interactive domain 5B (MRF1-like)
ARMC4 armadillo repeat containing 4
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ASB1 ankyrin repeat and SOCS box containing 1
ASL argininosuccinate lyase
ASXL1 additional sex combs like transcriptional regulator 1
ATM ATM serine/threonine kinase
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide
ATR ATR serine/threonine kinase
AZGP1 alpha-2-glycoprotein 1, zinc-binding
B3GNT5 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
BAG3 BCL2-associated athanogene 3
BAG4 BCL2-associated athanogene 4
BANK1 B-cell scaffold protein with ankyrin repeats 1
BAX BCL2-associated X protein
BBC3 BCL2 binding component 3
BCL10 B-cell CLL/lymphoma 10
BCL2 B-cell CLL/lymphoma 2
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BCL3 B-cell CLL/lymphoma 3
BCL6 B-cell CLL/lymphoma 6
BCO2 beta-carotene oxygenase 2
BECN1 beclin 1, autophagy related
BHLHE40 basic helix-loop-helix family, member e40
BIN3 bridging integrator 3
BIRC3 baculoviral IAP repeat containing 3
BLNK B-cell linker
BMF Bcl2 modifying factor
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
BOK BCL2-related ovarian killer
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA2 breast cancer 2, early onset
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
BST2 bone marrow stromal cell antigen 2
BTK Bruton agammaglobulinemia tyrosine kinase
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
C1ORF127 chromosome 1 open reading frame 127
C3 complement component 3
C4A complement component 4A (Rodgers blood group)
C5AR1 complement component 5a receptor 1
C6ORF25 chromosome 6 open reading frame 25
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CACNB4 calcium channel, voltage-dependent, beta 4 subunit
CACYBP calcyclin binding protein
CARD11 caspase recruitment domain family, member 11
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CBFB core-binding factor, beta subunit
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC151 coiled-coil domain containing 151
CCDC39 coiled-coil domain containing 39
CCNE1 cyclin E1
CCR2 chemokine (C-C motif) receptor 2
CCR7 chemokine (C-C motif) receptor 7
CD19 CD19 molecule
CD200 CD200 molecule
CD22 CD22 molecule
CD247 CD247 molecule
CD28 CD28 molecule
CD2AP CD2-associated protein
CD34 CD34 molecule
CD37 CD37 molecule
CD3G CD3g molecule, gamma (CD3-TCR complex)
CD4 CD4 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CD47 CD47 molecule
CD72 CD72 molecule
CD79A CD79a molecule, immunoglobulin-associated alpha
CD79B CD79b molecule, immunoglobulin-associated beta
CD84 CD84 molecule
CD86 CD86 molecule
CDH17 cadherin 17, LI cadherin (liver-intestine)
CDK6 cyclin-dependent kinase 6
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CEP290 centrosomal protein 290kDa
CFC1 cripto, FRL-1, cryptic family 1
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHD2 chromodomain helicase DNA binding protein 2
CIDEB cell death-inducing DFFA-like effector b
CISH cytokine inducible SH2-containing protein
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
COL10A1 collagen, type X, alpha 1
COMMD3-BMI1 COMMD3-BMI1 readthrough
CORO1A coronin, actin binding protein, 1A
CP ceruloplasmin (ferroxidase)
CR2 complement component (3d/Epstein Barr virus) receptor 2
CREBBP CREB binding protein
CRH corticotropin releasing hormone
CSF1 colony stimulating factor 1 (macrophage)
CSF1R colony stimulating factor 1 receptor
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CTC1 CTS telomere maintenance complex component 1
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTSA cathepsin A
CTSD cathepsin D
CTSG cathepsin G
CXCL13 chemokine (C-X-C motif) ligand 13
CXCR2 chemokine (C-X-C motif) receptor 2
CXCR4 chemokine (C-X-C motif) receptor 4
CXCR5 chemokine (C-X-C motif) receptor 5
CYCS cytochrome c, somatic
CYLD cylindromatosis (turban tumor syndrome)
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYS1 cystin 1
DAW1 dynein assembly factor with WDR repeat domains 1
DBNL drebrin-like
DCC DCC netrin 1 receptor
DCK deoxycytidine kinase
DCLRE1C DNA cross-link repair 1C
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DEDD death effector domain containing
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DIAPH1 diaphanous-related formin 1
DIDO1 death inducer-obliterator 1
DKC1 dyskeratosis congenita 1, dyskerin
DLK1 delta-like 1 homolog (Drosophila)
DNAH11 dynein, axonemal, heavy chain 11
DNAH5 dynein, axonemal, heavy chain 5
DNAI1 dynein, axonemal, intermediate chain 1
DNASE1 deoxyribonuclease I
DOCK2 dedicator of cytokinesis 2
DOCK8 dedicator of cytokinesis 8
DRC1 dynein regulatory complex subunit 1
DRD2 dopamine receptor D2
DTX1 deltex 1, E3 ubiquitin ligase
DUSP6 dual specificity phosphatase 6
DYX1C1 dyslexia susceptibility 1 candidate 1
E2F2 E2F transcription factor 2
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EGLN1 egl-9 family hypoxia-inducible factor 1
EGR1 early growth response 1
ELAVL1 ELAV like RNA binding protein 1
ELMOD1 ELMO/CED-12 domain containing 1
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
EPAS1 endothelial PAS domain protein 1
EPB41 erythrocyte membrane protein band 4.1
EPB42 erythrocyte membrane protein band 4.2
EPGN epithelial mitogen
EPO erythropoietin
EPOR erythropoietin receptor
EPS15 epidermal growth factor receptor pathway substrate 15
ERAP1 endoplasmic reticulum aminopeptidase 1
ERCC1 excision repair cross-complementation group 1
ERCC2 excision repair cross-complementation group 2
ERCC5 excision repair cross-complementation group 5
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
ESRRA estrogen-related receptor alpha
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
EWSR1 EWS RNA-binding protein 1
EXOC6 exocyst complex component 6
F9 coagulation factor IX
FADS2 fatty acid desaturase 2
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FBXL5 F-box and leucine-rich repeat protein 5
FCAMR Fc receptor, IgA, IgM, high affinity
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FCMR Fc fragment of IgM receptor
FECH ferrochelatase
FEN1 flap structure-specific endonuclease 1
FGF10 fibroblast growth factor 10
FGF23 fibroblast growth factor 23
FGF7 fibroblast growth factor 7
FIG4 FIG4 phosphoinositide 5-phosphatase
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FLT3 fms-related tyrosine kinase 3
FLT3LG fms-related tyrosine kinase 3 ligand
FLVCR1 feline leukemia virus subgroup C cellular receptor 1
FNIP1 folliculin interacting protein 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXN1 forkhead box N1
FOXO3 forkhead box O3
FOXP3 forkhead box P3
FSHR follicle stimulating hormone receptor
FXR1 fragile X mental retardation, autosomal homolog 1
FZD9 frizzled class receptor 9
GABPB2 GA binding protein transcription factor, beta subunit 2
GADD45B growth arrest and DNA-damage-inducible, beta
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1
GAPT GRB2-binding adaptor protein, transmembrane
GATA1 GATA binding protein 1 (globin transcription factor 1)
GBA glucosidase, beta, acid
GDF1 growth differentiation factor 1
GDF11 growth differentiation factor 11
GDNF glial cell derived neurotrophic factor
GGT1 gamma-glutamyltransferase 1
GHR growth hormone receptor
GIMAP1-GIMAP5 GIMAP1-GIMAP5 readthrough
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GLB1 galactosidase, beta 1
GLMP glycosylated lysosomal membrane protein
GLRA1 glycine receptor, alpha 1
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GON4L gon-4-like (C. elegans)
GPC3 glypican 3
GPI glucose-6-phosphate isomerase
GPR132 G protein-coupled receptor 132
GPR83 G protein-coupled receptor 83
GPX7 glutathione peroxidase 7
GRB14 growth factor receptor-bound protein 14
GSTK1 glutathione S-transferase kappa 1
GSTZ1 glutathione S-transferase zeta 1
HAMP hepcidin antimicrobial peptide
HAVCR1 hepatitis A virus cellular receptor 1
HAX1 HCLS1 associated protein X-1
HCST hematopoietic cell signal transducer
HELLS helicase, lymphoid-specific
HFE hemochromatosis
HFE2 hemochromatosis type 2 (juvenile)
HHIP hedgehog interacting protein
HK1 hexokinase 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HMGA1 high mobility group AT-hook 1
HMOX1 heme oxygenase 1
HOXA9 homeobox A9
HOXB4 homeobox B4
HPRT1 hypoxanthine phosphoribosyltransferase 1
HSH2D hematopoietic SH2 domain containing
HTRA2 HtrA serine peptidase 2
HYAL2 hyaluronoglucosaminidase 2
ICOS inducible T-cell co-stimulator
ICOSLG inducible T-cell co-stimulator ligand
IFNB1 interferon, beta 1, fibroblast
IFNG interferon, gamma
IFNGR1 interferon gamma receptor 1
IFT140 intraflagellar transport 140
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGHM immunoglobulin heavy constant mu
IGKC immunoglobulin kappa constant
IGLL1 immunoglobulin lambda-like polypeptide 1
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IKZF3 IKAROS family zinc finger 3 (Aiolos)
IL10 interleukin 10
IL10RB interleukin 10 receptor, beta
IL2 interleukin 2
IL21 interleukin 21
IL2RA interleukin 2 receptor, alpha
IL2RB interleukin 2 receptor, beta
IL2RG interleukin 2 receptor, gamma
IL31RA interleukin 31 receptor A
IL6ST interleukin 6 signal transducer
IL7 interleukin 7
IL7R interleukin 7 receptor
INCA1 inhibitor of CDK, cyclin A1 interacting protein 1
ING1 inhibitor of growth family, member 1
ING2 inhibitor of growth family, member 2
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
INVS inversin
IREB2 iron-responsive element binding protein 2
IRF1 interferon regulatory factor 1
IRF4 interferon regulatory factor 4
IRF8 interferon regulatory factor 8
ITFG2 integrin alpha FG-GAP repeat containing 2
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGAD integrin, alpha D
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
JAK1 Janus kinase 1
JAK2 Janus kinase 2
JAK3 Janus kinase 3
JARID2 jumonji, AT rich interactive domain 2
KAT6A K(lysine) acetyltransferase 6A
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KDM8 lysine (K)-specific demethylase 8
KIAA0101 KIAA0101
KISS1R KISS1 receptor
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KL klotho
KLF1 Kruppel-like factor 1 (erythroid)
KLF13 Kruppel-like factor 13
KLF3 Kruppel-like factor 3 (basic)
KLHL6 kelch-like family member 6
KLRK1 killer cell lectin-like receptor subfamily K, member 1
KMT2A lysine (K)-specific methyltransferase 2A
KMT2E lysine (K)-specific methyltransferase 2E
KRT8 keratin 8, type II
LAG3 lymphocyte-activation gene 3
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LAMP2 lysosomal-associated membrane protein 2
LAT linker for activation of T cells
LAT2 linker for activation of T cells family, member 2
LAX1 lymphocyte transmembrane adaptor 1
LBR lamin B receptor
LCN2 lipocalin 2
LDHA lactate dehydrogenase A
LEFTY2 left-right determination factor 2
LEP leptin
LEPR leptin receptor
LGMN legumain
LHCGR luteinizing hormone/choriogonadotropin receptor
LIG1 ligase I, DNA, ATP-dependent
LIG4 ligase IV, DNA, ATP-dependent
LIPA lipase A, lysosomal acid, cholesterol esterase
LMNA lamin A/C
LRFN2 leucine rich repeat and fibronectin type III domain containing 2
LTA lymphotoxin alpha
LTB lymphotoxin beta (TNF superfamily, member 3)
LTBP4 latent transforming growth factor beta binding protein 4
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3)
LTF lactotransferrin
LYN LYN proto-oncogene, Src family tyrosine kinase
LYZ lysozyme
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MALT1 MALT1 paracaspase
MAML1 mastermind-like 1 (Drosophila)
MAN2A1 mannosidase, alpha, class 2A, member 1
MAN2B1 mannosidase, alpha, class 2B, member 1
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MARCO macrophage receptor with collagenous structure
MARK2 MAP/microtubule affinity-regulating kinase 2
MARVELD2 MARVEL domain containing 2
MAVS mitochondrial antiviral signaling protein
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
MCM2 minichromosome maintenance complex component 2
MCM4 minichromosome maintenance complex component 4
MDC1 mediator of DNA-damage checkpoint 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MEFV Mediterranean fever
MEGF8 multiple EGF-like-domains 8
MERTK MER proto-oncogene, tyrosine kinase
MFGE8 milk fat globule-EGF factor 8 protein
MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
MFSD8 major facilitator superfamily domain containing 8
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MIR144 microRNA 144
MIR155 microRNA 155
MIR451A microRNA 451a
MITF microphthalmia-associated transcription factor
MKS1 Meckel syndrome, type 1
MORF4L1 mortality factor 4 like 1
MPL MPL proto-oncogene, thrombopoietin receptor
MPZL3 myelin protein zero-like 3
MSI2 musashi RNA-binding protein 2
MST1R macrophage stimulating 1 receptor
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MTSS1 metastasis suppressor 1
MXI1 MAX interactor 1, dimerization protein
MXRA7 matrix-remodelling associated 7
MYB v-myb avian myeloblastosis viral oncogene homolog
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
NBEAL2 neurobeachin-like 2
NCAPH2 non-SMC condensin II complex, subunit H2
NCKAP1L NCK-associated protein 1-like
NCOA3 nuclear receptor coactivator 3
NCOR2 nuclear receptor corepressor 2
NDFIP1 Nedd4 family interacting protein 1
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NEU1 sialidase 1 (lysosomal sialidase)
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NFE2 nuclear factor, erythroid 2
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NFKBID nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
NHEJ1 nonhomologous end-joining factor 1
NKX2-3 NK2 homeobox 3
NKX2-5 NK2 homeobox 5
NKX3-2 NK3 homeobox 2
NLK nemo-like kinase
NLRC5 NLR family, CARD domain containing 5
NLRP12 NLR family, pyrin domain containing 12
NLRP3 NLR family, pyrin domain containing 3
NODAL nodal growth differentiation factor
NOTCH1 notch 1
NOTCH2 notch 2
NPC1 Niemann-Pick disease, type C1
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NPR2 natriuretic peptide receptor 2
NPY1R neuropeptide Y receptor Y1
NR1H4 nuclear receptor subfamily 1, group H, member 4
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
OCA2 oculocutaneous albinism II
PAPPA2 pappalysin 2
PARL presenilin associated, rhomboid-like
PARP14 poly (ADP-ribose) polymerase family, member 14
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PAWR PRKC, apoptosis, WT1, regulator
PBX1 pre-B-cell leukemia homeobox 1
PCGF3 polycomb group ring finger 3
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase
PCSK1 proprotein convertase subtilisin/kexin type 1
PDCD1 programmed cell death 1
PDPK1 3-phosphoinositide dependent protein kinase 1
PECAM1 platelet/endothelial cell adhesion molecule 1
PFDN1 prefoldin subunit 1
PFKM phosphofructokinase, muscle
PGAP3 post-GPI attachment to proteins 3
PGM3 phosphoglucomutase 3
PHC1 polyhomeotic homolog 1 (Drosophila)
PI16 peptidase inhibitor 16
PICALM phosphatidylinositol binding clathrin assembly protein
PIK3AP1 phosphoinositide-3-kinase adaptor protein 1
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIKFYVE phosphoinositide kinase, FYVE finger containing
PITX2 paired-like homeodomain 2
PKD2 polycystic kidney disease 2 (autosomal dominant)
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive)
PKLR pyruvate kinase, liver and RBC
PKN1 protein kinase N1
PLA2G15 phospholipase A2, group XV
PLCD1 phospholipase C, delta 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PNP purine nucleoside phosphorylase
POLB polymerase (DNA directed), beta
POLE polymerase (DNA directed), epsilon, catalytic subunit
POU2AF1 POU class 2 associating factor 1
PPIA peptidylprolyl isomerase A (cyclophilin A)
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PPP5C protein phosphatase 5, catalytic subunit
PPT1 palmitoyl-protein thioesterase 1
PPT2 palmitoyl-protein thioesterase 2
PRDX1 peroxiredoxin 1
PRDX2 peroxiredoxin 2
PREP prolyl endopeptidase
PRF1 perforin 1 (pore forming protein)
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit
PRKCD protein kinase C, delta
PRKCZ protein kinase C, zeta
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRKG1 protein kinase, cGMP-dependent, type I
PRNP prion protein
PSAP prosaposin
PSIP1 PC4 and SFRS1 interacting protein 1
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
PTCH2 patched 2
PTEN phosphatase and tensin homolog
PTF1A pancreas specific transcription factor, 1a
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTP4A2 protein tyrosine phosphatase type IVA, member 2
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTPRC protein tyrosine phosphatase, receptor type, C
PTPRJ protein tyrosine phosphatase, receptor type, J
PTTG1 pituitary tumor-transforming 1
PURA purine-rich element binding protein A
RAD50 RAD50 homolog (S. cerevisiae)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RAG1 recombination activating gene 1
RAG2 recombination activating gene 2
RAPGEF6 Rap guanine nucleotide exchange factor (GEF) 6
RASA3 RAS p21 protein activator 3
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RASSF5 Ras association (RalGDS/AF-6) domain family member 5
RBL1 retinoblastoma-like 1
RC3H1 ring finger and CCCH-type domains 1
RECQL4 RecQ protein-like 4
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RFTN1 raftlin, lipid raft linker 1
RGS1 regulator of G-protein signaling 1
RGS13 regulator of G-protein signaling 13
RHBDF1 rhomboid 5 homolog 1 (Drosophila)
RHOH ras homolog family member H
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
RNF8 ring finger protein 8, E3 ubiquitin protein ligase
RORA RAR-related orphan receptor A
RORC RAR-related orphan receptor C
RPL27A ribosomal protein L27a
RRAS2 related RAS viral (r-ras) oncogene homolog 2
RRM2B ribonucleotide reductase M2 B (TP53 inducible)
RUNX1 runt-related transcription factor 1
RUNX2 runt-related transcription factor 2
S1PR2 sphingosine-1-phosphate receptor 2
SAC3D1 SAC3 domain containing 1
SAMD9L sterile alpha motif domain containing 9-like
SASH3 SAM and SH3 domain containing 3
SATB1 SATB homeobox 1
SCARF1 scavenger receptor class F, member 1
SCG5 secretogranin V
SELE selectin E
SELENBP1 selenium binding protein 1
SELL selectin L
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2
SFN stratifin
SGPL1 sphingosine-1-phosphate lyase 1
SGSH N-sulfoglucosamine sulfohydrolase
SH2B3 SH2B adaptor protein 3
SH2D1A SH2 domain containing 1A
SH2D3C SH2 domain containing 3C
SH3BP2 SH3-domain binding protein 2
SHARPIN SHANK-associated RH domain interactor
SIAE sialic acid acetylesterase
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin
SIPA1 signal-induced proliferation-associated 1
SIRT1 sirtuin 1
SIRT6 sirtuin 6
SKIL SKI-like proto-oncogene
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SMAD3 SMAD family member 3
SMAP1 small ArfGAP 1
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SMURF2 SMAD specific E3 ubiquitin protein ligase 2
SNORD50A small nucleolar RNA, C/D box 50A
SNORD50B small nucleolar RNA, C/D box 50B
SNX27 sorting nexin family member 27
SOCS1 suppressor of cytokine signaling 1
SOCS3 suppressor of cytokine signaling 3
SOS1 son of sevenless homolog 1 (Drosophila)
SOX11 SRY (sex determining region Y)-box 11
SP4 Sp4 transcription factor
SPI1 Spi-1 proto-oncogene
SPIB Spi-B transcription factor (Spi-1/PU.1 related)
SPIC Spi-C transcription factor (Spi-1/PU.1 related)
SPINK1 serine peptidase inhibitor, Kazal type 1
SPPL2A signal peptide peptidase like 2A
SPTA1 spectrin, alpha, erythrocytic 1
SPTB spectrin, beta, erythrocytic
SRPX sushi-repeat containing protein, X-linked
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
STEAP3 STEAP family member 3, metalloreductase
STIM1 stromal interaction molecule 1
STK11 serine/threonine kinase 11
STK36 serine/threonine kinase 36
STK4 serine/threonine kinase 4
SYK spleen tyrosine kinase
T T, brachyury homolog (mouse)
TAL1 T-cell acute lymphocytic leukemia 1
TANK TRAF family member-associated NFKB activator
TBC1D32 TBC1 domain family, member 32
TBC1D4 TBC1 domain family, member 4
TBK1 TANK-binding kinase 1
TBXA2R thromboxane A2 receptor
TCF21 transcription factor 21
TCF3 transcription factor 3
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
TDP2 tyrosyl-DNA phosphodiesterase 2
TERC telomerase RNA component
TERT telomerase reverse transcriptase
TET2 tet methylcytosine dioxygenase 2
TFR2 transferrin receptor 2
TFRC transferrin receptor
TGFB1 transforming growth factor, beta 1
TGFBI transforming growth factor, beta-induced, 68kDa
TGFBR3 transforming growth factor, beta receptor III
THBD thrombomodulin
THEMIS thymocyte selection associated
TK1 thymidine kinase 1, soluble
TLR4 toll-like receptor 4
TLR7 toll-like receptor 7
TLR8 toll-like receptor 8
TLX1 T-cell leukemia homeobox 1
TMPRSS6 transmembrane protease, serine 6
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFAIP8L2 tumor necrosis factor, alpha-induced protein 8-like 2
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TNIP1 TNFAIP3 interacting protein 1
TNS3 tensin 3
TOM1L2 target of myb1-like 2 (chicken)
TOP3B topoisomerase (DNA) III beta
TOX thymocyte selection-associated high mobility group box
TP53 tumor protein p53
TPI1 triosephosphate isomerase 1
TPO thyroid peroxidase
TPP2 tripeptidyl peptidase II
TPX2 TPX2, microtubule-associated
TRADD TNFRSF1A-associated via death domain
TRAF2 TNF receptor-associated factor 2
TRAF3 TNF receptor-associated factor 3
TRAF3IP2 TRAF3 interacting protein 2
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRAT1 T cell receptor associated transmembrane adaptor 1
TREX1 three prime repair exonuclease 1
TRIB1 tribbles pseudokinase 1
TRIM21 tripartite motif containing 21
TRIP10 thyroid hormone receptor interactor 10
TSPAN33 tetraspanin 33
TTC7A tetratricopeptide repeat domain 7A
TWIST2 twist family bHLH transcription factor 2
TWSG1 twisted gastrulation BMP signaling modulator 1
TYROBP TYRO protein tyrosine kinase binding protein
ULK1 unc-51 like autophagy activating kinase 1
UNC13D unc-13 homolog D (C. elegans)
UNC93B1 unc-93 homolog B1 (C. elegans)
UNG uracil-DNA glycosylase
UROS uroporphyrinogen III synthase
USP21 ubiquitin specific peptidase 21
VAV1 vav 1 guanine nucleotide exchange factor
VAV2 vav 2 guanine nucleotide exchange factor
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
WAS Wiskott-Aldrich syndrome
WT1 Wilms tumor 1
WWOX WW domain containing oxidoreductase
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZC3H12A zinc finger CCCH-type containing 12A
ZDHHC13 zinc finger, DHHC-type containing 13
ZEB1 zinc finger E-box binding homeobox 1
ZFP36 ZFP36 ring finger protein
ZFP36L2 ZFP36 ring finger protein-like 2
ZFPM1 zinc finger protein, FOG family member 1
ZIC3 Zic family member 3