abnormal renal glomerular filtration Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description anomaly in the process in which plasma is filtered through the glomerular membrane which consists of capillary endothelial cells, the basement membrane, and epithelial cells (Mammalian Phenotype Ontology, MP_0013284)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0013284
Similar Terms
Downloads & Tools


23 gene mutations causing the abnormal renal glomerular filtration phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
CYBB cytochrome b-245, beta polypeptide
FXYD4 FXYD domain containing ion transport regulator 4
GRM1 glutamate receptor, metabotropic 1
HNF1A HNF1 homeobox A
INS insulin
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
LAMB2 laminin, beta 2 (laminin S)
LGMN legumain
MAS1 MAS1 proto-oncogene, G protein-coupled receptor
MYO1E myosin IE
PARP1 poly (ADP-ribose) polymerase 1
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPRO protein tyrosine phosphatase, receptor type, O
REN renin
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1
SGK1 serum/glucocorticoid regulated kinase 1
SLC4A5 solute carrier family 4 (sodium bicarbonate cotransporter), member 5
UMOD uromodulin
VEGFA vascular endothelial growth factor A