abnormal pro-b cell differentiation Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description atypical production of or inability to produce the progenitor cells of the B cell lineage, with some lineage specific activity such as early stages of recombination of B cell receptor genes, but are not yet fully committed to the B cell lineage until the expression of PAX5 occurs (Mammalian Phenotype Ontology, MP_0008233)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008233
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Genes

3 gene mutations causing the abnormal pro-b cell differentiation phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
CD79B CD79b molecule, immunoglobulin-associated beta
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11