abnormal plasma cell differentiation Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description atypical production of or inability to produce terminally differentiated, post-mitotic, short-lived cells of the B cell lineage devoted to producing large amounts of immunoglobulin (Mammalian Phenotype Ontology, MP_0008099)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008099
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Genes

6 gene mutations causing the abnormal plasma cell differentiation phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
BLNK B-cell linker
CD36 CD36 molecule (thrombospondin receptor)
IGHM immunoglobulin heavy constant mu
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
PRKCD protein kinase C, delta
SIGLEC10 sialic acid binding Ig-like lectin 10