abnormal peyer's patch size Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description anomaly in the size of the protruding lymphoid tissue located on the mucosa of the small intestine that is composed of densely packed B cell follicles (Mammalian Phenotype Ontology, MP_0008134)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008134
Similar Terms
Downloads & Tools

Genes

36 gene mutations causing the abnormal peyer's patch size phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
BCL3 B-cell CLL/lymphoma 3
CACNB4 calcium channel, voltage-dependent, beta 4 subunit
CCR7 chemokine (C-C motif) receptor 7
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CXCL13 chemokine (C-X-C motif) ligand 13
CYLD cylindromatosis (turban tumor syndrome)
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
FAS Fas cell surface death receptor
GCSAM germinal center-associated, signaling and motility
ICOS inducible T-cell co-stimulator
IGHM immunoglobulin heavy constant mu
IL2RG interleukin 2 receptor, gamma
IRAK3 interleukin-1 receptor-associated kinase 3
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGB7 integrin, beta 7
JAK3 Janus kinase 3
LYN LYN proto-oncogene, Src family tyrosine kinase
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NKX2-3 NK2 homeobox 3
NLRP6 NLR family, pyrin domain containing 6
NOD2 nucleotide-binding oligomerization domain containing 2
PRKCZ protein kinase C, zeta
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PTEN phosphatase and tensin homolog
PYCARD PYD and CARD domain containing
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RGS1 regulator of G-protein signaling 1
RUNX1 runt-related transcription factor 1
SPPL2A signal peptide peptidase like 2A
TNF tumor necrosis factor
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TOX thymocyte selection-associated high mobility group box