abnormal pericardial cavity morphology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any structural anomaly of the anatomical body cavity in which the heart lies; the pericardial cavity forms in the lateral plate mesoderm above the buccopharyngeal membrane, as part of the early intraembryonic coelom, and is initially continuous with the two early pleural cavities (Mammalian Phenotype Ontology, MP_0012501)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0012501
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44 gene mutations causing the abnormal pericardial cavity morphology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ANKRD17 ankyrin repeat domain 17
BRAF B-Raf proto-oncogene, serine/threonine kinase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CBFB core-binding factor, beta subunit
CCM2 cerebral cavernous malformation 2
CXADR coxsackie virus and adenovirus receptor
DLL4 delta-like 4 (Drosophila)
F2 coagulation factor II (thrombin)
F2R coagulation factor II (thrombin) receptor
FBN1 fibrillin 1
FLT4 fms-related tyrosine kinase 4
FOXH1 forkhead box H1
GAB1 GRB2-associated binding protein 1
GYS1 glycogen synthase 1 (muscle)
HAND1 heart and neural crest derivatives expressed 1
HEG1 heart development protein with EGF-like domains 1
HHEX hematopoietically expressed homeobox
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HOPX HOP homeobox
HSPG2 heparan sulfate proteoglycan 2
ITGB8 integrin, beta 8
JUP junction plakoglobin
LATS2 large tumor suppressor kinase 2
LPAR4 lysophosphatidic acid receptor 4
MUS81 MUS81 structure-specific endonuclease subunit
NACA nascent polypeptide-associated complex alpha subunit
PKD1 polycystic kidney disease 1 (autosomal dominant)
PKP2 plakophilin 2
POR P450 (cytochrome) oxidoreductase
PTPRJ protein tyrosine phosphatase, receptor type, J
RHEB Ras homolog enriched in brain
RTEL1 regulator of telomere elongation helicase 1
RUNX1 runt-related transcription factor 1
RXRA retinoid X receptor, alpha
T T, brachyury homolog (mouse)
TCF21 transcription factor 21
TDG thymine-DNA glycosylase
TGFBR1 transforming growth factor, beta receptor 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TMSB4X thymosin beta 4, X-linked
VCL vinculin
WASF2 WAS protein family, member 2
WT1 Wilms tumor 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase