abnormal pancreatic beta cell morphology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any structural anomaly of a cell that secretes insulin and is located towards the center of the islets of Langerhans in the pancreas (Mammalian Phenotype Ontology, MP_0005217)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0005217
Similar Terms
Downloads & Tools

Genes

97 gene mutations causing the abnormal pancreatic beta cell morphology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8
ADIPOR2 adiponectin receptor 2
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2
AKAP5 A kinase (PRKA) anchor protein 5
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALMS1 Alstrom syndrome protein 1
ALX3 ALX homeobox 3
ANXA7 annexin A7
AQP7 aquaporin 7
ARX aristaless related homeobox
ASIP agouti signaling protein
ATF4 activating transcription factor 4
ATXN2 ataxin 2
B2M beta-2-microglobulin
BGLAP bone gamma-carboxyglutamate (gla) protein
BID BH3 interacting domain death agonist
BRD2 bromodomain containing 2
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CADM1 cell adhesion molecule 1
CD38 CD38 molecule
CDK4 cyclin-dependent kinase 4
COL5A3 collagen, type V, alpha 3
CPE carboxypeptidase E
CREBBP CREB binding protein
CYB5R4 cytochrome b5 reductase 4
DACH1 dachshund family transcription factor 1
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
E2F1 E2F transcription factor 1
EGFR epidermal growth factor receptor
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
FGF10 fibroblast growth factor 10
FSTL3 follistatin-like 3 (secreted glycoprotein)
GCGR glucagon receptor
GCK glucokinase (hexokinase 4)
GDF11 growth differentiation factor 11
GHR growth hormone receptor
GLIS3 GLIS family zinc finger 3
HNF1A HNF1 homeobox A
HPRT1 hypoxanthine phosphoribosyltransferase 1
ILDR2 immunoglobulin-like domain containing receptor 2
INS insulin
INSL5 insulin-like 5
INSM1 insulinoma-associated 1
INSR insulin receptor
IRS1 insulin receptor substrate 1
IRS2 insulin receptor substrate 2
KL klotho
LEP leptin
LEPR leptin receptor
LIPE lipase, hormone-sensitive
MEN1 multiple endocrine neoplasia I
MIR184 microRNA 184
MIR375 microRNA 375
MNX1 motor neuron and pancreas homeobox 1
MUT methylmalonyl CoA mutase
MYD88 myeloid differentiation primary response 88
NEUROD1 neuronal differentiation 1
NEUROG3 neurogenin 3
NKX2-2 NK2 homeobox 2
NKX6-1 NK6 homeobox 1
ONECUT1 one cut homeobox 1
OSMR oncostatin M receptor
PARG poly (ADP-ribose) glycohydrolase
PAX2 paired box 2
PAX4 paired box 4
PAX6 paired box 6
PCSK2 proprotein convertase subtilisin/kexin type 2
PDX1 pancreatic and duodenal homeobox 1
PGR progesterone receptor
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PRF1 perforin 1 (pore forming protein)
PRKCD protein kinase C, delta
PRLR prolactin receptor
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTTG1 pituitary tumor-transforming 1
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1
RIPPLY3 ripply transcriptional repressor 3
RPS6 ribosomal protein S6
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RPSA ribosomal protein SA
SCG5 secretogranin V
SEC23B Sec23 homolog B (S. cerevisiae)
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae)
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SERTAD1 SERTA domain containing 1
SIDT2 SID1 transmembrane family, member 2
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SOX9 SRY (sex determining region Y)-box 9
SPOP speckle-type POZ protein
SSTR5 somatostatin receptor 5
STAT4 signal transducer and activator of transcription 4
SYTL4 synaptotagmin-like 4
TLE3 transducin-like enhancer of split 3
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
WFS1 Wolfram syndrome 1 (wolframin)