abnormal pancreatic acinus morphology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any structural anomaly of the secretory units of the exocrine pancreas, where fluid containing digestive enzymes is produced; consists of a group of secretory cells surrounding a luminal space that connects to the pancreatic duct (Mammalian Phenotype Ontology, MP_0009145)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0009145
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36 gene mutations causing the abnormal pancreatic acinus morphology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
A2M alpha-2-macroglobulin
AGTR2 angiotensin II receptor, type 2
AQP12A aquaporin 12A
ATF4 activating transcription factor 4
BHLHA15 basic helix-loop-helix family, member a15
BRAF B-Raf proto-oncogene, serine/threonine kinase
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CYS1 cystin 1
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
GDF11 growth differentiation factor 11
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
IFT88 intraflagellar transport 88
INVS inversin
ISL1 ISL LIM homeobox 1
MAN2B1 mannosidase, alpha, class 2B, member 1
MEN1 multiple endocrine neoplasia I
NEUROD1 neuronal differentiation 1
NEUROG3 neurogenin 3
PDX1 pancreatic and duodenal homeobox 1
PGM3 phosphoglucomutase 3
PKD1 polycystic kidney disease 1 (autosomal dominant)
PPT2 palmitoyl-protein thioesterase 2
PROX1 prospero homeobox 1
RHBDF1 rhomboid 5 homolog 1 (Drosophila)
RPH3AL rabphilin 3A-like (without C2 domains)
SC5D sterol-C5-desaturase
SEC23B Sec23 homolog B (S. cerevisiae)
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2
SLC39A5 solute carrier family 39 (zinc transporter), member 5
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1
SPINK1 serine peptidase inhibitor, Kazal type 1
SYTL1 synaptotagmin-like 1
TK1 thymidine kinase 1, soluble
VAMP8 vesicle-associated membrane protein 8
YIPF6 Yip1 domain family, member 6