abnormal osteoblast cell number Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description deviation from the average number of the skeletogenic cells that secrete osteoid, are capable of producing mineralized (hydroxyapatite) matrix, are located adjacent to or within osteoid tissue, and arise from the transformation of a preosteoblast cell (Mammalian Phenotype Ontology, MP_0004987)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0004987
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Genes

54 gene mutations causing the abnormal osteoblast cell number phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ADIPOQ adiponectin, C1Q and collagen domain containing
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase)
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ATF4 activating transcription factor 4
BGN biglycan
CLCN7 chloride channel, voltage-sensitive 7
CNN1 calponin 1, basic, smooth muscle
CRH corticotropin releasing hormone
CTHRC1 collagen triple helix repeat containing 1
EBF1 early B-cell factor 1
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
ESRRA estrogen-related receptor alpha
FBLIM1 filamin binding LIM protein 1
FGFR1 fibroblast growth factor receptor 1
FGFR2 fibroblast growth factor receptor 2
FOS FBJ murine osteosarcoma viral oncogene homolog
FZD9 frizzled class receptor 9
GATA1 GATA binding protein 1 (globin transcription factor 1)
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
IDUA iduronidase, alpha-L-
IGF2 insulin-like growth factor 2
IHH indian hedgehog
IL6ST interleukin 6 signal transducer
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
IRAK3 interleukin-1 receptor-associated kinase 3
IRS1 insulin receptor substrate 1
ITGB1BP1 integrin beta 1 binding protein 1
JAM2 junctional adhesion molecule 2
KL klotho
KLF10 Kruppel-like factor 10
LRP5 low density lipoprotein receptor-related protein 5
MIA3 melanoma inhibitory activity family, member 3
MMP2 matrix metallopeptidase 2
NFE2 nuclear factor, erythroid 2
NPR3 natriuretic peptide receptor 3
NPY4R neuropeptide Y receptor Y4
NXN nucleoredoxin
PER1 period circadian clock 1
PPARG peroxisome proliferator-activated receptor gamma
PTH parathyroid hormone
PTHLH parathyroid hormone-like hormone
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RUNX2 runt-related transcription factor 2
SH3BP2 SH3-domain binding protein 2
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC30A5 solute carrier family 30 (zinc transporter), member 5
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
TGFB1 transforming growth factor, beta 1
TNF tumor necrosis factor
TOB1 transducer of ERBB2, 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor