abnormal orientation of inner hair cell stereociliary bundles Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description misorientation or rotation of inner hair cell (IHC) stereociliary bundles, resulting in defective planar cell polarity of the inner ear sensory epithelium (Mammalian Phenotype Ontology, MP_0004492)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0004492
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Genes

12 gene mutations causing the abnormal orientation of inner hair cell stereociliary bundles phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
CDH23 cadherin-related 23
FGFR1 fibroblast growth factor receptor 1
JAG2 jagged 2
MYO6 myosin VI
MYO7A myosin VIIA
NR2F1 nuclear receptor subfamily 2, group F, member 1
PCDH15 protocadherin-related 15
PTK7 protein tyrosine kinase 7 (inactive)
PTPRQ protein tyrosine phosphatase, receptor type, Q
SEC24B SEC24 family member B
USH1C Usher syndrome 1C (autosomal recessive, severe)
VANGL2 VANGL planar cell polarity protein 2