abnormal organ of corti supporting cell morphology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any structural anomaly in the highly differentiated epithelial cells with distinctive morphological features surrounding the hair cells in the organ of Corti; inner hair cells (IHCs) are normally surrounded by (inner and outer) phalangeal cells while OHCs are in contact with Deiters and pillar cells; Hensen cells are positioned further laterally in the organ of Corti (Mammalian Phenotype Ontology, MP_0004300)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0004300
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Genes

33 gene mutations causing the abnormal organ of corti supporting cell morphology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ADGRV1 adhesion G protein-coupled receptor V1
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1
CLRN1 clarin 1
CYS1 cystin 1
ESPN espin
FBXO2 F-box protein 2
FGF20 fibroblast growth factor 20
FGFR1 fibroblast growth factor receptor 1
FGFR3 fibroblast growth factor receptor 3
GATA3 GATA binding protein 3
GFI1 growth factor independent 1 transcription repressor
JAG2 jagged 2
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
LAMA2 laminin, alpha 2
NR2F1 nuclear receptor subfamily 2, group F, member 1
OTOA otoancorin
PAX8 paired box 8
PCDH15 protocadherin-related 15
POU4F3 POU class 4 homeobox 3
PSAP prosaposin
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC26A5 solute carrier family 26 (anion exchanger), member 5
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7
SOD1 superoxide dismutase 1, soluble
SPRY2 sprouty homolog 2 (Drosophila)
SRRM4 serine/arginine repetitive matrix 4
THRB thyroid hormone receptor, beta
TMC1 transmembrane channel-like 1
TUB tubby bipartite transcription factor