abnormal nk cell physiology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0010766
Similar Terms
Downloads & Tools

Genes

92 gene mutations causing the abnormal nk cell physiology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ATF2 activating transcription factor 2
BLOC1S3 biogenesis of lysosomal organelles complex-1, subunit 3
BLOC1S6 biogenesis of lysosomal organelles complex-1, subunit 6, pallidin
CARD11 caspase recruitment domain family, member 11
CD226 CD226 molecule
CD244 CD244 molecule, natural killer cell receptor 2B4
CD247 CD247 molecule
CD28 CD28 molecule
CD44 CD44 molecule (Indian blood group)
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma
CLNK cytokine-dependent hematopoietic cell linker
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCR4 chemokine (C-X-C motif) receptor 4
DTNBP1 dystrobrevin binding protein 1
ELF4 E74-like factor 4 (ets domain transcription factor)
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FLT3 fms-related tyrosine kinase 3
FOXQ1 forkhead box Q1
FYN FYN proto-oncogene, Src family tyrosine kinase
GADD45G growth arrest and DNA-damage-inducible, gamma
GFI1 growth factor independent 1 transcription repressor
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HCST hematopoietic cell signal transducer
HLA-G major histocompatibility complex, class I, G
HPS1 Hermansky-Pudlak syndrome 1
ICOS inducible T-cell co-stimulator
IFNAR1 interferon (alpha, beta and omega) receptor 1
IFNAR2 interferon (alpha, beta and omega) receptor 2
IFNG interferon, gamma
IFNGR1 interferon gamma receptor 1
IL12A interleukin 12A
IL12B interleukin 12B
IL12RB2 interleukin 12 receptor, beta 2
IL15 interleukin 15
IL15RA interleukin 15 receptor, alpha
IL18 interleukin 18
IL18R1 interleukin 18 receptor 1
IL2 interleukin 2
IL21R interleukin 21 receptor
IL2RG interleukin 2 receptor, gamma
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
IRAK4 interleukin-1 receptor-associated kinase 4
IRF1 interferon regulatory factor 1
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
KLRK1 killer cell lectin-like receptor subfamily K, member 1
LAG3 lymphocyte-activation gene 3
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
LGMN legumain
LYST lysosomal trafficking regulator
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYD88 myeloid differentiation primary response 88
NCR1 natural cytotoxicity triggering receptor 1
NFIL3 nuclear factor, interleukin 3 regulated
NFKBID nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta
NPC2 Niemann-Pick disease, type C2
OCA2 oculocutaneous albinism II
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PRDX1 peroxiredoxin 1
PRF1 perforin 1 (pore forming protein)
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PTPRC protein tyrosine phosphatase, receptor type, C
RAB27A RAB27A, member RAS oncogene family
RAG1 recombination activating gene 1
RAG2 recombination activating gene 2
RHBDD3 rhomboid domain containing 3
RNF19B ring finger protein 19B
S1PR5 sphingosine-1-phosphate receptor 5
SH2D1A SH2 domain containing 1A
SH2D1B SH2 domain containing 1B
SLAMF7 SLAM family member 7
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT4 signal transducer and activator of transcription 4
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
STX11 syntaxin 11
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TAPBP TAP binding protein (tapasin)
TBX21 T-box 21
TICAM1 toll-like receptor adaptor molecule 1
TLR3 toll-like receptor 3
TLR9 toll-like receptor 9
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TXNIP thioredoxin interacting protein
TYROBP TYRO protein tyrosine kinase binding protein
UNC13D unc-13 homolog D (C. elegans)
VAV1 vav 1 guanine nucleotide exchange factor
XPA xeroderma pigmentosum, complementation group A