abnormal neural fold formation Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any anomaly in the process by which the edges of the neural plate thicken and move up to form a U-shaped structure called the neural groove (Mammalian Phenotype Ontology, MP_0004837)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0004837
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Genes

28 gene mutations causing the abnormal neural fold formation phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AMBRA1 autophagy/beclin-1 regulator 1
BCL10 B-cell CLL/lymphoma 10
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CSNK2A1 casein kinase 2, alpha 1 polypeptide
DISP1 dispatched homolog 1 (Drosophila)
FGF8 fibroblast growth factor 8 (androgen-induced)
FGFR1 fibroblast growth factor receptor 1
GPR161 G protein-coupled receptor 161
GRHL2 grainyhead-like 2 (Drosophila)
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
JARID2 jumonji, AT rich interactive domain 2
LMO4 LIM domain only 4
MESP1 mesoderm posterior basic helix-loop-helix transcription factor 1
MIXL1 Mix paired-like homeobox
NODAL nodal growth differentiation factor
PAX3 paired box 3
POGLUT1 protein O-glucosyltransferase 1
POR P450 (cytochrome) oxidoreductase
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
SMO smoothened, frizzled class receptor
STK11 serine/threonine kinase 11
T T, brachyury homolog (mouse)
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
TCOF1 Treacher Collins-Franceschetti syndrome 1
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
VCL vinculin
ZIC2 Zic family member 2