abnormal neural crest cell physiology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any functional anomaly in the complex process by which multipotent neural crest progenitors acquire migratory and invasive properties, emigrate from the dorsal aspect of the neural tube, migrate along distinct pathways, and differentiate into diverse cell types (Mammalian Phenotype Ontology, MP_0012745)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0012745
Similar Terms
Downloads & Tools

Genes

33 gene mutations causing the abnormal neural crest cell physiology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ADAMTS20 ADAM metallopeptidase with thrombospondin type 1 motif, 20
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
CAPNS1 calpain, small subunit 1
CFL1 cofilin 1 (non-muscle)
CHD7 chromodomain helicase DNA binding protein 7
CHRD chordin
EFNB1 ephrin-B1
EFNB2 ephrin-B2
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
EXT1 exostosin glycosyltransferase 1
FGF8 fibroblast growth factor 8 (androgen-induced)
FGFR1 fibroblast growth factor receptor 1
FOLR1 folate receptor 1 (adult)
FOXI3 forkhead box I3
GBX2 gastrulation brain homeobox 2
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HOXA1 homeobox A1
JUN jun proto-oncogene
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
MED12 mediator complex subunit 12
NRG1 neuregulin 1
OVOL2 ovo-like zinc finger 2
PAX3 paired box 3
PDPK1 3-phosphoinositide dependent protein kinase 1
PHOX2B paired-like homeobox 2b
RET ret proto-oncogene
RIPPLY3 ripply transcriptional repressor 3
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SOX10 SRY (sex determining region Y)-box 10
TBX1 T-box 1
TCOF1 Treacher Collins-Franceschetti syndrome 1
ZEB2 zinc finger E-box binding homeobox 2