abnormal nephron number Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description anomaly in the total number of the filtering units of the kidney; nephron number can be used as an index of the efficiency of ureteric branching and nephrogenesis (Mammalian Phenotype Ontology, MP_0011289)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0011289
Similar Terms
Downloads & Tools

Genes

17 gene mutations causing the abnormal nephron number phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
BCL2 B-cell CLL/lymphoma 2
BMP7 bone morphogenetic protein 7
BMPER BMP binding endothelial regulator
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
DLG1 discs, large homolog 1 (Drosophila)
FGF7 fibroblast growth factor 7
FGFR2 fibroblast growth factor receptor 2
GDF11 growth differentiation factor 11
GDNF glial cell derived neurotrophic factor
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
ILK integrin-linked kinase
PAX2 paired box 2
PBX1 pre-B-cell leukemia homeobox 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
SIX2 SIX homeobox 2
TCF21 transcription factor 21
TRPS1 trichorhinophalangeal syndrome I