abnormal mitosis Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description anomaly in the process of cell division including both division of the nucleus (karyokinesis) and the cytoplasm (cytokinesis) (Mammalian Phenotype Ontology, MP_0004046)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0004046
Similar Terms
Downloads & Tools

Genes

89 gene mutations causing the abnormal mitosis phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ATR ATR serine/threonine kinase
AURKA aurora kinase A
AURKB aurora kinase B
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BIRC5 baculoviral IAP repeat containing 5
BRAP BRCA1 associated protein
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
BUB3 BUB3 mitotic checkpoint protein
CD79A CD79a molecule, immunoglobulin-associated alpha
CDC20 cell division cycle 20
CDC25A cell division cycle 25A
CDCA8 cell division cycle associated 8
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CENPA centromere protein A
CENPC centromere protein C
CENPE centromere protein E, 312kDa
CENPJ centromere protein J
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
CTNND1 catenin (cadherin-associated protein), delta 1
DICER1 dicer 1, ribonuclease type III
DIDO1 death inducer-obliterator 1
DNA2 DNA replication helicase/nuclease 2
E4F1 E4F transcription factor 1
EDNRB endothelin receptor type B
EGR1 early growth response 1
EIF6 eukaryotic translation initiation factor 6
ESCO2 establishment of sister chromatid cohesion N-acetyltransferase 2
EYA1 EYA transcriptional coactivator and phosphatase 1
FANCM Fanconi anemia, complementation group M
FBXO5 F-box protein 5
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GADD45A growth arrest and DNA-damage-inducible, alpha
GFI1 growth factor independent 1 transcription repressor
GMNN geminin, DNA replication inhibitor
HAT1 histone acetyltransferase 1
KAT8 K(lysine) acetyltransferase 8
KIF18A kinesin family member 18A
KIF20B kinesin family member 20B
LATS1 large tumor suppressor kinase 1
LATS2 large tumor suppressor kinase 2
LIG3 ligase III, DNA, ATP-dependent
LMNA lamin A/C
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MAGOH mago-nashi homolog, proliferation-associated (Drosophila)
MASTL microtubule associated serine/threonine kinase-like
MCPH1 microcephalin 1
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIS18A MIS18 kinetochore protein A
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
NEK7 NIMA-related kinase 7
NUSAP1 nucleolar and spindle associated protein 1
PARP1 poly (ADP-ribose) polymerase 1
PARP2 poly (ADP-ribose) polymerase 2
PAX3 paired box 3
PAXIP1 PAX interacting (with transcription-activation domain) protein 1
PDS5A PDS5 cohesin associated factor A
PDS5B PDS5 cohesin associated factor B
PIFO primary cilia formation
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive)
PLK1 polo-like kinase 1
PLK4 polo-like kinase 4
PRICKLE1 prickle homolog 1 (Drosophila)
PRIMPOL primase and polymerase (DNA-directed)
RAE1 ribonucleic acid export 1
RB1 retinoblastoma 1
RECQL RecQ helicase-like
RECQL5 RecQ protein-like 5
RGPD1 RANBP2-like and GRIP domain containing 1
RIF1 replication timing regulatory factor 1
RTEL1 regulator of telomere elongation helicase 1
SIRT1 sirtuin 1
SIRT2 sirtuin 2
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
SPG20 spastic paraplegia 20 (Troyer syndrome)
STAG1 stromal antigen 1
TACC3 transforming, acidic coiled-coil containing protein 3
TADA3 transcriptional adaptor 3
TDP2 tyrosyl-DNA phosphodiesterase 2
TPX2 TPX2, microtubule-associated
TSG101 tumor susceptibility 101
TTYH1 tweety family member 1
TUBG1 tubulin, gamma 1
USP44 ubiquitin specific peptidase 44
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon