abnormal microglial cell activation Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any anomaly in change in morphology and behavior of a microglial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, during the maturation to the fully active phagocytic form (Mammalian Phenotype Ontology, MP_0010762)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0010762
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Genes

11 gene mutations causing the abnormal microglial cell activation phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
CCL3L3 chemokine (C-C motif) ligand 3-like 3
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
MAN2C1 mannosidase, alpha, class 2C, member 1
NEIL3 nei endonuclease VIII-like 3 (E. coli)
NPC1 Niemann-Pick disease, type C1
PPT1 palmitoyl-protein thioesterase 1
PTPN6 protein tyrosine phosphatase, non-receptor type 6
SARM1 sterile alpha and TIR motif containing 1
TLR2 toll-like receptor 2
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)