abnormal marginal zone b cell physiology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description abnormal function of a CD23-negative, CD21-positive B cell of the marginal zone of the spleen expressing a B cell receptor usually reactive to bacterial cell wall components or senescent self components such as oxidized-LDL (Mammalian Phenotype Ontology, MP_0008193)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008193
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Genes

7 gene mutations causing the abnormal marginal zone b cell physiology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
BCL10 B-cell CLL/lymphoma 10
FCAMR Fc receptor, IgA, IgM, high affinity
SASH3 SAM and SH3 domain containing 3
SH2D3C SH2 domain containing 3C
SH3BP2 SH3-domain binding protein 2
ZNF318 zinc finger protein 318