abnormal mammary gland morphology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any structural anomaly of the compound, alveolar and apocrine accessory gland of the skin of mammals that secretes milk (Mammalian Phenotype Ontology, MP_0000627)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0000627
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Genes

119 gene mutations causing the abnormal mammary gland morphology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ADAM17 ADAM metallopeptidase domain 17
AEBP1 AE binding protein 1
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AGPAT6 1-acylglycerol-3-phosphate O-acyltransferase 6
AHR aryl hydrocarbon receptor
ANPEP alanyl (membrane) aminopeptidase
APC adenomatous polyposis coli
AREG amphiregulin
ARHGAP5 Rho GTPase activating protein 5
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BECN1 beclin 1, autophagy related
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
BSX brain-specific homeobox
BTN1A1 butyrophilin, subfamily 1, member A1
CAV1 caveolin 1, caveolae protein, 22kDa
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCND1 cyclin D1
CCNE1 cyclin E1
CD44 CD44 molecule (Indian blood group)
CDH3 cadherin 3, type 1, P-cadherin (placental)
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CHUK conserved helix-loop-helix ubiquitous kinase
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
CSF1 colony stimulating factor 1 (macrophage)
CSF1R colony stimulating factor 1 receptor
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DDR1 discoidin domain receptor tyrosine kinase 1
EDAR ectodysplasin A receptor
EGFR epidermal growth factor receptor
ELF5 E74-like factor 5 (ets domain transcription factor)
ERBB3 erb-b2 receptor tyrosine kinase 3
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
ETV4 ets variant 4
FGF10 fibroblast growth factor 10
FGFR2 fibroblast growth factor receptor 2
FKBP4 FK506 binding protein 4, 59kDa
FOXA1 forkhead box A1
FOXB1 forkhead box B1
GAL galanin/GMAP prepropeptide
GJA1 gap junction protein, alpha 1, 43kDa
GLI3 GLI family zinc finger 3
GPRC6A G protein-coupled receptor, class C, group 6, member A
GSN gelsolin
HOXC6 homeobox C6
HPRT1 hypoxanthine phosphoribosyltransferase 1
HPSE heparanase
HR hair growth associated
HRAS Harvey rat sarcoma viral oncogene homolog
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IL13 interleukin 13
IL4 interleukin 4
IL6 interleukin 6
IL6ST interleukin 6 signal transducer
INHBB inhibin, beta B
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
KISS1R KISS1 receptor
LALBA lactalbumin, alpha-
LATS1 large tumor suppressor kinase 1
LBH limb bud and heart development
LEF1 lymphoid enhancer-binding factor 1
LEP leptin
LIF leukemia inhibitory factor
LRP4 low density lipoprotein receptor-related protein 4
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MED1 mediator complex subunit 1
MFGE8 milk fat globule-EGF factor 8 protein
MKL1 megakaryoblastic leukemia (translocation) 1
MSX2 msh homeobox 2
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NCOA1 nuclear receptor coactivator 1
NCOA3 nuclear receptor coactivator 3
NEO1 neogenin 1
NEURL1 neuralized E3 ubiquitin protein ligase 1
NME1 NME/NM23 nucleoside diphosphate kinase 1
NOS2 nitric oxide synthase 2, inducible
NPY4R neuropeptide Y receptor Y4
NRG1 neuregulin 1
NRG3 neuregulin 3
NTN1 netrin 1
OXT oxytocin/neurophysin I prepropeptide
PAX3 paired box 3
PGR progesterone receptor
PHB prohibitin
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLG plasminogen
PRL prolactin
PRLR prolactin receptor
PROKR2 prokineticin receptor 2
PTPRF protein tyrosine phosphatase, receptor type, F
PXMP2 peroxisomal membrane protein 2, 22kDa
RB1 retinoblastoma 1
RLN1 relaxin 1
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RXFP1 relaxin/insulin-like family peptide receptor 1
SFN stratifin
SIRT1 sirtuin 1
SIRT2 sirtuin 2
SLC30A4 solute carrier family 30 (zinc transporter), member 4
SLIT2 slit homolog 2 (Drosophila)
SOCS5 suppressor of cytokine signaling 5
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
TBX3 T-box 3
TIMP3 TIMP metallopeptidase inhibitor 3
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TP53 tumor protein p53
TP63 tumor protein p63
UBE3A ubiquitin protein ligase E3A
XDH xanthine dehydrogenase
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
ZNF613 zinc finger protein 613