abnormal male germ cell apoptosis Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description presence of male germs cells that undergo programmed cell death (Mammalian Phenotype Ontology, MP_0008280)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008280
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Genes

111 gene mutations causing the abnormal male germ cell apoptosis phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ADRA1B adrenoceptor alpha 1B
ADRM1 adhesion regulating molecule 1
AGO4 argonaute RISC catalytic component 4
AHR aryl hydrocarbon receptor
ALKBH5 AlkB family member 5, RNA demethylase
AR androgen receptor
ATAT1 alpha tubulin acetyltransferase 1
BAX BCL2-associated X protein
BCL6 B-cell CLL/lymphoma 6
BMP8A bone morphogenetic protein 8a
BMP8B bone morphogenetic protein 8b
BOLL boule-like RNA-binding protein
CCDC79 coiled-coil domain containing 79
CCNA1 cyclin A1
CD59 CD59 molecule, complement regulatory protein
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CHTF18 CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)
CIT citron rho-interacting serine/threonine kinase
CNOT7 CCR4-NOT transcription complex, subunit 7
CPEB1 cytoplasmic polyadenylation element binding protein 1
CSNK2A2 casein kinase 2, alpha prime polypeptide
CTCFL CCCTC-binding factor (zinc finger protein)-like
CUL4A cullin 4A
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
DDR2 discoidin domain receptor tyrosine kinase 2
DDX25 DEAD (Asp-Glu-Ala-Asp) box helicase 25
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
DMRTC2 DMRT-like family C2
EGR4 early growth response 4
EHD1 EH-domain containing 1
EHD4 EH-domain containing 4
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3
ELMO1 engulfment and cell motility 1
ETV5 ets variant 5
EXO1 exonuclease 1
FANCA Fanconi anemia, complementation group A
GOLGA3 golgin A3
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GTSF1 gametocyte specific factor 1
HIP1 huntingtin interacting protein 1
HORMAD1 HORMA domain containing 1
HORMAD2 HORMA domain containing 2
HOXA11 homeobox A11
HSF2 heat shock transcription factor 2
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA4 heat shock 70kDa protein 4
INSL6 insulin-like 6
JMJD1C jumonji domain containing 1C
KDM3A lysine (K)-specific demethylase 3A
KDM4D lysine (K)-specific demethylase 4D
KIF18A kinesin family member 18A
LHB luteinizing hormone beta polypeptide
LHCGR luteinizing hormone/choriogonadotropin receptor
LIMK2 LIM domain kinase 2
M1AP meiosis 1 associated protein
MAEL maelstrom spermatogenic transposon silencer
MCM8 minichromosome maintenance complex component 8
MCM9 minichromosome maintenance complex component 9
MCPH1 microcephalin 1
MEIG1 meiosis/spermiogenesis associated 1
MEIOB meiosis specific with OB domains
MOV10L1 Mov10 RISC complex RNA helicase like 1
MSH5 mutS homolog 5
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NR1H3 nuclear receptor subfamily 1, group H, member 3
NXF2 nuclear RNA export factor 2
PAPOLB poly(A) polymerase beta (testis specific)
PEA15 phosphoprotein enriched in astrocytes 15
PHF13 PHD finger protein 13
PICK1 protein interacting with PRKCA 1
PIWIL2 piwi-like RNA-mediated gene silencing 2
PLD6 phospholipase D family, member 6
PLEKHA5 pleckstrin homology domain containing, family A member 5
PRDX4 peroxiredoxin 4
PSME4 proteasome (prosome, macropain) activator subunit 4
PUM1 pumilio RNA-binding family member 1
RAD21L1 RAD21-like 1 (S. pombe)
RANBP1 RAN binding protein 1
RANBP9 RAN binding protein 9
RARA retinoic acid receptor, alpha
RBM5 RNA binding motif protein 5
SAFB scaffold attachment factor B
SEPT12 septin 12
SIRT1 sirtuin 1
SLC25A31 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31
SLX4 SLX4 structure-specific endonuclease subunit
SMC1B structural maintenance of chromosomes 1B
SPAG16 sperm associated antigen 16
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
SYCE1 synaptonemal complex central element protein 1
SYCP2 synaptonemal complex protein 2
TAS1R1 taste receptor, type 1, member 1
TASP1 taspase, threonine aspartase, 1
TBPL1 TBP-like 1
TCTE3 t-complex-associated-testis-expressed 3
TDRD1 tudor domain containing 1
TDRD5 tudor domain containing 5
TDRD6 tudor domain containing 6
TDRD7 tudor domain containing 7
TDRD9 tudor domain containing 9
TERC telomerase RNA component
TERT telomerase reverse transcriptase
TP53 tumor protein p53
TSN translin
UBE2B ubiquitin-conjugating enzyme E2B
VASN vasorin
YBX2 Y box binding protein 2
ZBTB16 zinc finger and BTB domain containing 16
ZC3HC1 zinc finger, C3HC-type containing 1
ZNF148 zinc finger protein 148