abnormal major salivary gland morphology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any structural anomaly of the three largest glands of the oral cavity that secrete most of the saliva, including the parotid, submandibular, and sublingual glands (Mammalian Phenotype Ontology, MP_0003792)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0003792
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Genes

29 gene mutations causing the abnormal major salivary gland morphology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
BHLHA15 basic helix-loop-helix family, member a15
CCR7 chemokine (C-C motif) receptor 7
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
E2F1 E2F transcription factor 1
EDN1 endothelin 1
EDNRA endothelin receptor type A
EGFR epidermal growth factor receptor
FAS Fas cell surface death receptor
FGF10 fibroblast growth factor 10
FGFR2 fibroblast growth factor receptor 2
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MUC19 mucin 19, oligomeric
NKX2-3 NK2 homeobox 3
PAX6 paired box 6
PITX1 paired-like homeodomain 1
PRDM16 PR domain containing 16
RET ret proto-oncogene
RRM2B ribonucleotide reductase M2 B (TP53 inducible)
RXRA retinoid X receptor, alpha
SATB2 SATB homeobox 2
SEC23B Sec23 homolog B (S. cerevisiae)
SHH sonic hedgehog
SIX1 SIX homeobox 1
TFCP2L1 transcription factor CP2-like 1
TK1 thymidine kinase 1, soluble
TRAF3IP2 TRAF3 interacting protein 2
TWSG1 twisted gastrulation BMP signaling modulator 1