abnormal lymph node t cell domain morphology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any structural anomaly of the paracortex and interfollicular cortex of the lymph node in which T lymphocytes home to survey dendritic cells; T lymphocytes proliferate in the paracortex and enlarge it but do not produce structures analogous to germinal centers (Mammalian Phenotype Ontology, MP_0002347)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0002347
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Genes

5 gene mutations causing the abnormal lymph node t cell domain morphology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
CCR7 chemokine (C-C motif) receptor 7
CD4 CD4 molecule
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
FOXN1 forkhead box N1
FOXP3 forkhead box P3