abnormal lymph node size Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description deviation from the normal lymph node size (Mammalian Phenotype Ontology, MP_0000701)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0000701
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Genes

151 gene mutations causing the abnormal lymph node size phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ANK1 ankyrin 1, erythrocytic
ATM ATM serine/threonine kinase
B3GNT5 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
BCL2 B-cell CLL/lymphoma 2
BCL3 B-cell CLL/lymphoma 3
BHLHE40 basic helix-loop-helix family, member e40
BIRC3 baculoviral IAP repeat containing 3
BST2 bone marrow stromal cell antigen 2
CACNB4 calcium channel, voltage-dependent, beta 4 subunit
CARD11 caspase recruitment domain family, member 11
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCR7 chemokine (C-C motif) receptor 7
CCRL2 chemokine (C-C motif) receptor-like 2
CD200 CD200 molecule
CD247 CD247 molecule
CD3G CD3g molecule, gamma (CD3-TCR complex)
CD40LG CD40 ligand
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon
CHD2 chromodomain helicase DNA binding protein 2
CISH cytokine inducible SH2-containing protein
CLEC10A C-type lectin domain family 10, member A
CORO1A coronin, actin binding protein, 1A
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTSV cathepsin V
CXCR2 chemokine (C-X-C motif) receptor 2
CYLD cylindromatosis (turban tumor syndrome)
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
CYTIP cytohesin 1 interacting protein
DCLRE1C DNA cross-link repair 1C
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DOCK2 dedicator of cytokinesis 2
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
ESR2 estrogen receptor 2 (ER beta)
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FLT3 fms-related tyrosine kinase 3
FLT3LG fms-related tyrosine kinase 3 ligand
FOXC2 forkhead box C2
FOXN1 forkhead box N1
FOXO3 forkhead box O3
FOXP3 forkhead box P3
FPR2 formyl peptide receptor 2
FZD9 frizzled class receptor 9
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1
GIMAP1-GIMAP5 GIMAP1-GIMAP5 readthrough
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HMOX1 heme oxygenase 1
HPRT1 hypoxanthine phosphoribosyltransferase 1
ICOS inducible T-cell co-stimulator
IGHM immunoglobulin heavy constant mu
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL15 interleukin 15
IL15RA interleukin 15 receptor, alpha
IL2 interleukin 2
IL2RA interleukin 2 receptor, alpha
IL2RB interleukin 2 receptor, beta
IL2RG interleukin 2 receptor, gamma
IL34 interleukin 34
IL6ST interleukin 6 signal transducer
IL7 interleukin 7
IL7R interleukin 7 receptor
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
IRF2 interferon regulatory factor 2
IRF4 interferon regulatory factor 4
IRF8 interferon regulatory factor 8
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
JAK3 Janus kinase 3
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2
KMT2E lysine (K)-specific methyltransferase 2E
LAT linker for activation of T cells
LBR lamin B receptor
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
LYN LYN proto-oncogene, Src family tyrosine kinase
MARK2 MAP/microtubule affinity-regulating kinase 2
MCM4 minichromosome maintenance complex component 4
MEFV Mediterranean fever
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MSMB microseminoprotein, beta-
MUC2 mucin 2, oligomeric mucus/gel-forming
MYC v-myc avian myelocytomatosis viral oncogene homolog
NCKAP1L NCK-associated protein 1-like
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
NLK nemo-like kinase
NLRP3 NLR family, pyrin domain containing 3
PDCD1LG2 programmed cell death 1 ligand 2
PELI1 pellino E3 ubiquitin protein ligase 1
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PKP3 plakophilin 3
PLCD1 phospholipase C, delta 1
PLG plasminogen
PRKCD protein kinase C, delta
PRKCH protein kinase C, eta
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PTEN phosphatase and tensin homolog
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPRC protein tyrosine phosphatase, receptor type, C
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
RAG2 recombination activating gene 2
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RASSF5 Ras association (RalGDS/AF-6) domain family member 5
RC3H1 ring finger and CCCH-type domains 1
REL v-rel avian reticuloendotheliosis viral oncogene homolog
SATB1 SATB homeobox 1
SELL selectin L
SGPL1 sphingosine-1-phosphate lyase 1
SH2B3 SH2B adaptor protein 3
SH3BP2 SH3-domain binding protein 2
SIT1 signaling threshold regulating transmembrane adaptor 1
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SMAD3 SMAD family member 3
SNORD50A small nucleolar RNA, C/D box 50A
SNORD50B small nucleolar RNA, C/D box 50B
SPTA1 spectrin, alpha, erythrocytic 1
TANK TRAF family member-associated NFKB activator
TBXA2R thromboxane A2 receptor
TGFB1 transforming growth factor, beta 1
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TNIP1 TNFAIP3 interacting protein 1
TNS2 tensin 2
TP63 tumor protein p63
TRAF3IP2 TRAF3 interacting protein 2
TRAT1 T cell receptor associated transmembrane adaptor 1
TREX1 three prime repair exonuclease 1
TRIM21 tripartite motif containing 21
UNG uracil-DNA glycosylase
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZBTB46 zinc finger and BTB domain containing 46
ZC3H12A zinc finger CCCH-type containing 12A
ZEB1 zinc finger E-box binding homeobox 1
ZFP36 ZFP36 ring finger protein