abnormal lung lobe morphology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any structural anomaly of any of the anatomically and functionally distinct subunits (lobes) comprising the left or right lung, where each lobe receives air from its own secondary bronchus and is separated from it neighbors by one or more fissures (walls of connective tissue) (Mammalian Phenotype Ontology, MP_0010975)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0010975
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24 gene mutations causing the abnormal lung lobe morphology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
DNAH11 dynein, axonemal, heavy chain 11
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
FGF18 fibroblast growth factor 18
FGFR2 fibroblast growth factor receptor 2
FOXF1 forkhead box F1
FRAS1 Fraser extracellular matrix complex subunit 1
FREM1 FRAS1 related extracellular matrix 1
FSTL1 follistatin-like 1
GLI2 GLI family zinc finger 2
GLI3 GLI family zinc finger 3
GRHL2 grainyhead-like 2 (Drosophila)
IFT74 intraflagellar transport 74
ITGA8 integrin, alpha 8
KIF7 kinesin family member 7
MKS1 Meckel syndrome, type 1
PTK7 protein tyrosine kinase 7 (inactive)
SCRIB scribbled planar cell polarity protein
SEC24B SEC24 family member B
SHH sonic hedgehog
TCF21 transcription factor 21
VANGL2 VANGL planar cell polarity protein 2
ZFPM2 zinc finger protein, FOG family member 2