abnormal loop of henle ascending limb morphology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any structural anomaly of the distal part of the loop of Henle that is impermeable to water and actively pumps sodium out of the filtrate to generate the hypertonic interstitium that drives countercurrent exchange; it consists of an initial very thin segment lined by simple squamous epithelium followed by a distal thick segment lined by simple cuboidal epithelium (Mammalian Phenotype Ontology, MP_0011342)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0011342
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Genes

3 gene mutations causing the abnormal loop of henle ascending limb morphology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
INVS inversin
MKS1 Meckel syndrome, type 1
UMOD uromodulin