abnormal liver weight Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description anomaly in the average weight of the bile-secreting exocrine gland (Mammalian Phenotype Ontology, MP_0004847)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0004847
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Genes

149 gene mutations causing the abnormal liver weight phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5
ACOX1 acyl-CoA oxidase 1, palmitoyl
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AHR aryl hydrocarbon receptor
AIP aryl hydrocarbon receptor interacting protein
ALMS1 Alstrom syndrome protein 1
ANGPTL3 angiopoietin-like 3
ARF6 ADP-ribosylation factor 6
ASIP agouti signaling protein
ATR ATR serine/threonine kinase
BAG3 BCL2-associated athanogene 3
BCKDK branched chain ketoacid dehydrogenase kinase
BHMT betaine--homocysteine S-methyltransferase
BMP5 bone morphogenetic protein 5
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
CAV1 caveolin 1, caveolae protein, 22kDa
CCNG1 cyclin G1
CES1 carboxylesterase 1
CHST14 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14
CLCA2 chloride channel accessory 2
CRBN cereblon
CUL3 cullin 3
CXCL14 chemokine (C-X-C motif) ligand 14
CYBRD1 cytochrome b reductase 1
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial
DEDD death effector domain containing
DFNB31 deafness, autosomal recessive 31
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15
DRD2 dopamine receptor D2
DUSP1 dual specificity phosphatase 1
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4
EIF3M eukaryotic translation initiation factor 3, subunit M
EIF6 eukaryotic translation initiation factor 6
FABP2 fatty acid binding protein 2, intestinal
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FABP6 fatty acid binding protein 6, ileal
FADS2 fatty acid desaturase 2
FECH ferrochelatase
FFAR4 free fatty acid receptor 4
FGF21 fibroblast growth factor 21
FGL1 fibrinogen-like 1
G0S2 G0/G1 switch 2
G6PC glucose-6-phosphatase, catalytic subunit
GAB1 GRB2-associated binding protein 1
GBA glucosidase, beta, acid
GHR growth hormone receptor
GNMT glycine N-methyltransferase
GPER1 G protein-coupled estrogen receptor 1
GPI glucose-6-phosphate isomerase
GPR12 G protein-coupled receptor 12
GRB14 growth factor receptor-bound protein 14
GSTZ1 glutathione S-transferase zeta 1
GTF2IRD1 GTF2I repeat domain containing 1
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor
HNF1A HNF1 homeobox A
IFITM1 interferon induced transmembrane protein 1
IGF2 insulin-like growth factor 2
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP3 insulin-like growth factor binding protein 3
IL1R1 interleukin 1 receptor, type I
JUND jun D proto-oncogene
KCNQ1OT1 KCNQ1 opposite strand/antisense transcript 1 (non-protein coding)
KIFAP3 kinesin-associated protein 3
KISS1 KiSS-1 metastasis-suppressor
KISS1R KISS1 receptor
KL klotho
KLF3 Kruppel-like factor 3 (basic)
KLF6 Kruppel-like factor 6
KMT2B lysine (K)-specific methyltransferase 2B
LDHA lactate dehydrogenase A
LDLR low density lipoprotein receptor
LEP leptin
LEPR leptin receptor
LGMN legumain
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LIPA lipase A, lysosomal acid, cholesterol esterase
LTA lymphotoxin alpha
MAPK6 mitogen-activated protein kinase 6
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MARVELD2 MARVEL domain containing 2
MAT1A methionine adenosyltransferase I, alpha
MBD5 methyl-CpG binding domain protein 5
MC4R melanocortin 4 receptor
MDK midkine (neurite growth-promoting factor 2)
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MET MET proto-oncogene, receptor tyrosine kinase
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
MLXIPL MLX interacting protein-like
MSTN myostatin
NCOA3 nuclear receptor coactivator 3
NCOA6 nuclear receptor coactivator 6
NDFIP1 Nedd4 family interacting protein 1
NEGR1 neuronal growth regulator 1
NFE2L2 nuclear factor, erythroid 2-like 2
NOS3 nitric oxide synthase 3 (endothelial cell)
NPC1 Niemann-Pick disease, type C1
NPY6R neuropeptide Y receptor Y6 (pseudogene)
NR1H3 nuclear receptor subfamily 1, group H, member 3
NR1H4 nuclear receptor subfamily 1, group H, member 4
OCA2 oculocutaneous albinism II
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OSMR oncostatin M receptor
OTC ornithine carbamoyltransferase
PAPPA2 pappalysin 2
PKD2 polycystic kidney disease 2 (autosomal dominant)
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive)
PLA2G1B phospholipase A2, group IB (pancreas)
PNLIP pancreatic lipase
POMC proopiomelanocortin
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta
PREP prolyl endopeptidase
PRL prolactin
PSAP prosaposin
PTN pleiotrophin
RCAN2 regulator of calcineurin 2
RDH16 retinol dehydrogenase 16 (all-trans)
SC5D sterol-C5-desaturase
SELENBP1 selenium binding protein 1
SENP1 SUMO1/sentrin specific peptidase 1
SERPINA12 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
SERTAD2 SERTA domain containing 2
SIK3 SIK family kinase 3
SLC13A1 solute carrier family 13 (sodium/sulfate symporter), member 1
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC5A10 solute carrier family 5 (sodium/sugar cotransporter), member 10
SNORD50A small nucleolar RNA, C/D box 50A
SNORD50B small nucleolar RNA, C/D box 50B
SOD2 superoxide dismutase 2, mitochondrial
SPI1 Spi-1 proto-oncogene
SRA1 steroid receptor RNA activator 1
STARD10 StAR-related lipid transfer (START) domain containing 10
STARD4 StAR-related lipid transfer (START) domain containing 4
STEAP4 STEAP family member 4
STX2 syntaxin 2
THRA thyroid hormone receptor, alpha
TKT transketolase
TNF tumor necrosis factor
TP53 tumor protein p53
TXNIP thioredoxin interacting protein
WWOX WW domain containing oxidoreductase
XIRP2 xin actin binding repeat containing 2
XYLT2 xylosyltransferase II