abnormal leukocyte adhesion Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description anomaly in the number of or process by which leukocytes adhere to the luminal aspects of high endothelial venules prior to transmigration out of the vessel (Mammalian Phenotype Ontology, MP_0003628)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0003628
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Genes

38 gene mutations causing the abnormal leukocyte adhesion phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ADORA2B adenosine A2b receptor
AOC3 amine oxidase, copper containing 3
CAPN1 calpain 1, (mu/I) large subunit
CCR1 chemokine (C-C motif) receptor 1
CCR2 chemokine (C-C motif) receptor 2
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD40LG CD40 ligand
CD44 CD44 molecule (Indian blood group)
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
CTTN cortactin
CXCL13 chemokine (C-X-C motif) ligand 13
EDIL3 EGF-like repeats and discoidin I-like domains 3
F3 coagulation factor III (thromboplastin, tissue factor)
FAS Fas cell surface death receptor
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
FYB FYN binding protein
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
ICAM1 intercellular adhesion molecule 1
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITGB7 integrin, beta 7
LTB4R leukotriene B4 receptor
NFE2L2 nuclear factor, erythroid 2-like 2
NINJ1 ninjurin 1
NOS1 nitric oxide synthase 1 (neuronal)
NOS3 nitric oxide synthase 3 (endothelial cell)
PILRA paired immunoglobin-like type 2 receptor alpha
RAP1A RAP1A, member of RAS oncogene family
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
SELE selectin E
SELL selectin L
SELPLG selectin P ligand
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
STK4 serine/threonine kinase 4
THBD thrombomodulin
VIM vimentin