abnormal keratinocyte apoptosis Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description aberrant programmed cell death or anomaly in the number of the cells of the epidermis that produce keratin in the process of differentiating into the dead and fully keratinized cells of the stratum corneum (Mammalian Phenotype Ontology, MP_0001224)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0001224
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Genes

14 gene mutations causing the abnormal keratinocyte apoptosis phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
CASP3 caspase 3, apoptosis-related cysteine peptidase
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
ESR2 estrogen receptor 2 (ER beta)
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
KLF10 Kruppel-like factor 10
KRT14 keratin 14, type I
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
PKP3 plakophilin 3
PPARD peroxisome proliferator-activated receptor delta
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
SHARPIN SHANK-associated RH domain interactor
TREX2 three prime repair exonuclease 2
TYR tyrosinase