abnormal intraepithelial t cell number Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduced number of T cell present in columnar epithelia such as in the gastrointestinal tract; intraepithelial T cells often have distinct developmental pathways and activation requirements (Mammalian Phenotype Ontology, MP_0008895)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008895
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Genes

15 gene mutations causing the abnormal intraepithelial t cell number phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
B2M beta-2-microglobulin
CCL25 chemokine (C-C motif) ligand 25
CCR10 chemokine (C-C motif) receptor 10
CCR6 chemokine (C-C motif) receptor 6
CCR9 chemokine (C-C motif) receptor 9
CD247 CD247 molecule
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL15 interleukin 15
IL15RA interleukin 15 receptor, alpha
IL2RG interleukin 2 receptor, gamma
LCK LCK proto-oncogene, Src family tyrosine kinase
PIGR polymeric immunoglobulin receptor
PTPRC protein tyrosine phosphatase, receptor type, C
RC3H1 ring finger and CCCH-type domains 1