abnormal intestinal mucosa morphology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any structural anomaly of the mucous lining of the intestine; this consists of epithelium, lamina propria, and a layer of smooth muscle cells (Mammalian Phenotype Ontology, MP_0000511)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0000511
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Genes

119 gene mutations causing the abnormal intestinal mucosa morphology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
AGR2 anterior gradient 2
ANGPTL4 angiopoietin-like 4
APC adenomatous polyposis coli
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
B3GNT6 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BCL2 B-cell CLL/lymphoma 2
CA9 carbonic anhydrase IX
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CCNG1 cyclin G1
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CGN cingulin
CLDN15 claudin 15
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSD cathepsin D
CYBA cytochrome b-245, alpha polypeptide
CYBB cytochrome b-245, beta polypeptide
E2F4 E2F transcription factor 4, p107/p130-binding
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
ENPP7 ectonucleotide pyrophosphatase/phosphodiesterase 7
EPCAM epithelial cell adhesion molecule
EPHB2 EPH receptor B2
ESR2 estrogen receptor 2 (ER beta)
FADS2 fatty acid desaturase 2
FEN1 flap structure-specific endonuclease 1
FGF10 fibroblast growth factor 10
FGF9 fibroblast growth factor 9
FOLR1 folate receptor 1 (adult)
FOXL1 forkhead box L1
FOXP3 forkhead box P3
FPR2 formyl peptide receptor 2
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type
GCNT4 glucosaminyl (N-acetyl) transferase 4, core 2
GIMAP1-GIMAP5 GIMAP1-GIMAP5 readthrough
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GPX1 glutathione peroxidase 1
GUCA2A guanylate cyclase activator 2A (guanylin)
HDAC2 histone deacetylase 2
HPRT1 hypoxanthine phosphoribosyltransferase 1
HR hair growth associated
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1
IL10 interleukin 10
IL10RB interleukin 10 receptor, beta
IL13 interleukin 13
IL17RE interleukin 17 receptor E
IL2 interleukin 2
IL22 interleukin 22
IL25 interleukin 25
IL4 interleukin 4
IL4R interleukin 4 receptor
IL5 interleukin 5
IL9 interleukin 9
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
KLF4 Kruppel-like factor 4 (gut)
KLF5 Kruppel-like factor 5 (intestinal)
KRAS Kirsten rat sarcoma viral oncogene homolog
LAMA5 laminin, alpha 5
LEP leptin
LIPA lipase A, lysosomal acid, cholesterol esterase
LTBP4 latent transforming growth factor beta binding protein 4
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MCM2 minichromosome maintenance complex component 2
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
MUC2 mucin 2, oligomeric mucus/gel-forming
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MYC v-myc avian myelocytomatosis viral oncogene homolog
NCF1 neutrophil cytosolic factor 1
NEUROD1 neuronal differentiation 1
NFIL3 nuclear factor, interleukin 3 regulated
NKX2-3 NK2 homeobox 3
NLRP6 NLR family, pyrin domain containing 6
NR5A2 nuclear receptor subfamily 5, group A, member 2
NRIP1 nuclear receptor interacting protein 1
NUAK2 NUAK family, SNF1-like kinase, 2
PDX1 pancreatic and duodenal homeobox 1
PGLYRP1 peptidoglycan recognition protein 1
PGLYRP2 peptidoglycan recognition protein 2
PGLYRP3 peptidoglycan recognition protein 3
PGLYRP4 peptidoglycan recognition protein 4
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIP prolactin-induced protein
PLG plasminogen
POLG polymerase (DNA directed), gamma
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PYCARD PYD and CARD domain containing
RAG2 recombination activating gene 2
RC3H1 ring finger and CCCH-type domains 1
RUNX3 runt-related transcription factor 3
SAV1 salvador family WW domain containing protein 1
SEC23B Sec23 homolog B (S. cerevisiae)
SGOL1 shugoshin-like 1 (S. pombe)
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC26A3 solute carrier family 26 (anion exchanger), member 3
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SPDEF SAM pointed domain containing ETS transcription factor
STX2 syntaxin 2
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TERT telomerase reverse transcriptase
TFF1 trefoil factor 1
TFF2 trefoil factor 2
THRA thyroid hormone receptor, alpha
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TMPO thymopoietin
TP53 tumor protein p53
TP53INP1 tumor protein p53 inducible nuclear protein 1
TSTA3 tissue specific transplantation antigen P35B
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
WAS Wiskott-Aldrich syndrome
YIPF6 Yip1 domain family, member 6