abnormal intestinal epithelium morphology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any structural anomaly of the cellular avascular layer of the digestive tube passing from the stomach to the anus (Mammalian Phenotype Ontology, MP_0000488)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0000488
Similar Terms
Downloads & Tools

Genes

154 gene mutations causing the abnormal intestinal epithelium morphology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
AGR2 anterior gradient 2
ANGPT2 angiopoietin 2
ANGPTL4 angiopoietin-like 4
ANXA1 annexin A1
APC adenomatous polyposis coli
ATG14 autophagy related 14
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
B3GNT6 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BCL2 B-cell CLL/lymphoma 2
BRCA1 breast cancer 1, early onset
CA9 carbonic anhydrase IX
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CCNE1 cyclin E1
CCNG1 cyclin G1
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CGN cingulin
CLDN15 claudin 15
CRB3 crumbs family member 3
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSD cathepsin D
CX3CR1 chemokine (C-X3-C motif) receptor 1
CYBA cytochrome b-245, alpha polypeptide
CYBB cytochrome b-245, beta polypeptide
CYLD cylindromatosis (turban tumor syndrome)
E2F4 E2F transcription factor 4, p107/p130-binding
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
ENPP7 ectonucleotide pyrophosphatase/phosphodiesterase 7
EP300 E1A binding protein p300
EPCAM epithelial cell adhesion molecule
EPHB2 EPH receptor B2
ESR2 estrogen receptor 2 (ER beta)
EZR ezrin
FADS2 fatty acid desaturase 2
FEN1 flap structure-specific endonuclease 1
FGF10 fibroblast growth factor 10
FGF9 fibroblast growth factor 9
FOLR1 folate receptor 1 (adult)
FOXL1 forkhead box L1
FOXP3 forkhead box P3
FPR2 formyl peptide receptor 2
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type
GCNT4 glucosaminyl (N-acetyl) transferase 4, core 2
GIMAP1-GIMAP5 GIMAP1-GIMAP5 readthrough
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GPX1 glutathione peroxidase 1
GUCA2A guanylate cyclase activator 2A (guanylin)
HDAC2 histone deacetylase 2
HPRT1 hypoxanthine phosphoribosyltransferase 1
HR hair growth associated
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1
IGHM immunoglobulin heavy constant mu
IL10 interleukin 10
IL10RB interleukin 10 receptor, beta
IL13 interleukin 13
IL17RE interleukin 17 receptor E
IL2 interleukin 2
IL22 interleukin 22
IL25 interleukin 25
IL4 interleukin 4
IL4R interleukin 4 receptor
IL5 interleukin 5
IL9 interleukin 9
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
KLF4 Kruppel-like factor 4 (gut)
KLF5 Kruppel-like factor 5 (intestinal)
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT8 keratin 8, type II
LAMA5 laminin, alpha 5
LEP leptin
LEPR leptin receptor
LIPA lipase A, lysosomal acid, cholesterol esterase
LTBP4 latent transforming growth factor beta binding protein 4
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast)
MAN2C1 mannosidase, alpha, class 2C, member 1
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MCM2 minichromosome maintenance complex component 2
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
MUC2 mucin 2, oligomeric mucus/gel-forming
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
MYD88 myeloid differentiation primary response 88
MYO1A myosin IA
NCF1 neutrophil cytosolic factor 1
NEUROD1 neuronal differentiation 1
NFIL3 nuclear factor, interleukin 3 regulated
NKX2-3 NK2 homeobox 3
NLRP6 NLR family, pyrin domain containing 6
NR5A2 nuclear receptor subfamily 5, group A, member 2
NRIP1 nuclear receptor interacting protein 1
NUAK2 NUAK family, SNF1-like kinase, 2
PDGFA platelet-derived growth factor alpha polypeptide
PDGFC platelet derived growth factor C
PDX1 pancreatic and duodenal homeobox 1
PGLYRP1 peptidoglycan recognition protein 1
PGLYRP2 peptidoglycan recognition protein 2
PGLYRP3 peptidoglycan recognition protein 3
PGLYRP4 peptidoglycan recognition protein 4
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIP prolactin-induced protein
PITPNA phosphatidylinositol transfer protein, alpha
PLG plasminogen
POLG polymerase (DNA directed), gamma
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PYCARD PYD and CARD domain containing
RAB8A RAB8A, member RAS oncogene family
RAG2 recombination activating gene 2
RB1CC1 RB1-inducible coiled-coil 1
RC3H1 ring finger and CCCH-type domains 1
RETNLB resistin like beta
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
RUNX3 runt-related transcription factor 3
SAV1 salvador family WW domain containing protein 1
SEC23B Sec23 homolog B (S. cerevisiae)
SGOL1 shugoshin-like 1 (S. pombe)
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC26A3 solute carrier family 26 (anion exchanger), member 3
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SMTN smoothelin
SPDEF SAM pointed domain containing ETS transcription factor
STX2 syntaxin 2
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TDP2 tyrosyl-DNA phosphodiesterase 2
TERT telomerase reverse transcriptase
TFF1 trefoil factor 1
TFF2 trefoil factor 2
TFF3 trefoil factor 3 (intestinal)
TGFB1 transforming growth factor, beta 1
TGFB2 transforming growth factor, beta 2
TGFB3 transforming growth factor, beta 3
THRA thyroid hormone receptor, alpha
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TMPO thymopoietin
TNS3 tensin 3
TP53 tumor protein p53
TP53INP1 tumor protein p53 inducible nuclear protein 1
TP73 tumor protein p73
TSTA3 tissue specific transplantation antigen P35B
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
WAS Wiskott-Aldrich syndrome
WASF1 WAS protein family, member 1
YIPF6 Yip1 domain family, member 6