abnormal innervation Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description the malformation, misprojection, abnormal fasciculation or abnormal refinement of the connection, of nerve fibers to a target (Mammalian Phenotype Ontology, MP_0002184)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0002184
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Genes

150 gene mutations causing the abnormal innervation phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ACAN aggrecan
ADCY3 adenylate cyclase 3
AGA aspartylglucosaminidase
AGRN agrin
ALCAM activated leukocyte cell adhesion molecule
ALS2 amyotrophic lateral sclerosis 2 (juvenile)
ARHGAP35 Rho GTPase activating protein 35
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2
BDNF brain-derived neurotrophic factor
BMP4 bone morphogenetic protein 4
BOC BOC cell adhesion associated, oncogene regulated
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CACNA1F calcium channel, voltage-dependent, L type, alpha 1F subunit
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit
CACNB3 calcium channel, voltage-dependent, beta 3 subunit
CACNG2 calcium channel, voltage-dependent, gamma subunit 2
CALCB calcitonin-related polypeptide beta
CBLN1 cerebellin 1 precursor
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3
CHAT choline O-acetyltransferase
CHD7 chromodomain helicase DNA binding protein 7
CHL1 cell adhesion molecule L1-like
CHN1 chimerin 1
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle)
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
CHRNG cholinergic receptor, nicotinic, gamma (muscle)
CLIP3 CAP-GLY domain containing linker protein 3
CLP1 cleavage and polyadenylation factor I subunit 1
CNTN2 contactin 2 (axonal)
DCC DCC netrin 1 receptor
DLG4 discs, large homolog 4 (Drosophila)
DLX5 distal-less homeobox 5
DNER delta/notch-like EGF repeat containing
DOK7 docking protein 7
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
EBF2 early B-cell factor 2
EBF3 early B-cell factor 3
ECEL1 endothelin converting enzyme-like 1
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EFNA2 ephrin-A2
EFNA5 ephrin-A5
EFNB3 ephrin-B3
EGFR epidermal growth factor receptor
EGLN3 egl-9 family hypoxia-inducible factor 3
EN1 engrailed homeobox 1
EPG5 ectopic P-granules autophagy protein 5 homolog (C. elegans)
EPHA4 EPH receptor A4
EPHA5 EPH receptor A5
EPHB1 EPH receptor B1
EPHB2 EPH receptor B2
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB4 erb-b2 receptor tyrosine kinase 4
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
ETV1 ets variant 1
ETV4 ets variant 4
FBXO45 F-box protein 45
FFAR3 free fatty acid receptor 3
FGF10 fibroblast growth factor 10
FGFR3 fibroblast growth factor receptor 3
FRZB frizzled-related protein
GABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3
GAN gigaxonin
GAP43 growth associated protein 43
GARS glycyl-tRNA synthetase
GATA3 GATA binding protein 3
GBX2 gastrulation brain homeobox 2
GDNF glial cell derived neurotrophic factor
GFI1 growth factor independent 1 transcription repressor
GFRA1 GDNF family receptor alpha 1
GFRA3 GDNF family receptor alpha 3
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GPR143 G protein-coupled receptor 143
GRID2 glutamate receptor, ionotropic, delta 2
HOXB13 homeobox B13
HOXD1 homeobox D1
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
IGF1 insulin-like growth factor 1 (somatomedin C)
IGHMBP2 immunoglobulin mu binding protein 2
ISL2 ISL LIM homeobox 2
JAM3 junctional adhesion molecule 3
KAT6A K(lysine) acetyltransferase 6A
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KLF7 Kruppel-like factor 7 (ubiquitous)
L1CAM L1 cell adhesion molecule
LMNB1 lamin B1
LMX1B LIM homeobox transcription factor 1, beta
MET MET proto-oncogene, receptor tyrosine kinase
MNX1 motor neuron and pancreas homeobox 1
MUSK muscle, skeletal, receptor tyrosine kinase
MYO7A myosin VIIA
NDN necdin, melanoma antigen (MAGE) family member
NGF nerve growth factor (beta polypeptide)
NGFR nerve growth factor receptor
NKX2-8 NK2 homeobox 8
NME1 NME/NM23 nucleoside diphosphate kinase 1
NMNAT2 nicotinamide nucleotide adenylyltransferase 2
NPPC natriuretic peptide C
NPR2 natriuretic peptide receptor 2
NPTX1 neuronal pentraxin I
NPTX2 neuronal pentraxin II
NPTXR neuronal pentraxin receptor
NR5A1 nuclear receptor subfamily 5, group A, member 1
NRG1 neuregulin 1
NRP2 neuropilin 2
NTF3 neurotrophin 3
NTF4 neurotrophin 4
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
OLIG2 oligodendrocyte lineage transcription factor 2
OR10A2 olfactory receptor, family 10, subfamily A, member 2
OR10A4 olfactory receptor, family 10, subfamily A, member 4
OR10A5 olfactory receptor, family 10, subfamily A, member 5
OR8A1 olfactory receptor, family 8, subfamily A, member 1
PAX2 paired box 2
PAX8 paired box 8
PINK1 PTEN induced putative kinase 1
PLCB4 phospholipase C, beta 4
PLXNA4 plexin A4
POU4F2 POU class 4 homeobox 2
POU4F3 POU class 4 homeobox 3
PSAP prosaposin
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
RELN reelin
REN renin
RET ret proto-oncogene
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila)
RUNX3 runt-related transcription factor 3
SCRIB scribbled planar cell polarity protein
SCYL1 SCY1-like 1 (S. cerevisiae)
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SEMA3E sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SH2D3C SH2 domain containing 3C
SLC17A8 solute carrier family 17 (vesicular glutamate transporter), member 8
SLC18A3 solute carrier family 18 (vesicular acetylcholine transporter), member 3
SLC5A7 solute carrier family 5 (sodium/choline cotransporter), member 7
SLITRK6 SLIT and NTRK-like family, member 6
TENM2 teneurin transmembrane protein 2
TENM3 teneurin transmembrane protein 3
TLX2 T-cell leukemia homeobox 2
TOP2B topoisomerase (DNA) II beta 180kDa
TRPC2 transient receptor potential cation channel, subfamily C, member 2, pseudogene
UNC5C unc-5 homolog C (C. elegans)
VAX1 ventral anterior homeobox 1
VAX2 ventral anterior homeobox 2
ZEB1 zinc finger E-box binding homeobox 1