abnormal innate immunity Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description anomaly in the function of the early phase of the response to infection; normally, it is present at all times, does not increase with exposure to specific pathogens, and does not discriminate between pathogens (Mammalian Phenotype Ontology, MP_0002419)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0002419
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Genes

494 gene mutations causing the abnormal innate immunity phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ACP5 acid phosphatase 5, tartrate resistant
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
ADGRE1 adhesion G protein-coupled receptor E1
ADORA2B adenosine A2b receptor
ADORA3 adenosine A3 receptor
ADRB2 adrenoceptor beta 2, surface
AHR aryl hydrocarbon receptor
AIM2 absent in melanoma 2
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase)
ALOX5 arachidonate 5-lipoxygenase
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ANGPTL2 angiopoietin-like 2
ANPEP alanyl (membrane) aminopeptidase
ANXA1 annexin A1
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3
ARG1 arginase 1
ARHGAP15 Rho GTPase activating protein 15
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ASXL1 additional sex combs like transcriptional regulator 1
ATF2 activating transcription factor 2
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATG9A autophagy related 9A
ATM ATM serine/threonine kinase
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BAG4 BCL2-associated athanogene 4
BCL2A1 BCL2-related protein A1
BCL3 B-cell CLL/lymphoma 3
BCR breakpoint cluster region
BIRC3 baculoviral IAP repeat containing 3
BLOC1S3 biogenesis of lysosomal organelles complex-1, subunit 3
BLOC1S6 biogenesis of lysosomal organelles complex-1, subunit 6, pallidin
BTK Bruton agammaglobulinemia tyrosine kinase
C3 complement component 3
C3AR1 complement component 3a receptor 1
C5AR1 complement component 5a receptor 1
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CAPG capping protein (actin filament), gelsolin-like
CARD11 caspase recruitment domain family, member 11
CARD9 caspase recruitment domain family, member 9
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP4 caspase 4, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CCBE1 collagen and calcium binding EGF domains 1
CCL13 chemokine (C-C motif) ligand 13
CCL3L3 chemokine (C-C motif) ligand 3-like 3
CCR1 chemokine (C-C motif) receptor 1
CCR2 chemokine (C-C motif) receptor 2
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCR6 chemokine (C-C motif) receptor 6
CD14 CD14 molecule
CD200 CD200 molecule
CD226 CD226 molecule
CD244 CD244 molecule, natural killer cell receptor 2B4
CD247 CD247 molecule
CD28 CD28 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD44 CD44 molecule (Indian blood group)
CD47 CD47 molecule
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD68 CD68 molecule
CD69 CD69 molecule
CD81 CD81 molecule
CD93 CD93 molecule
CDH5 cadherin 5, type 2 (vascular endothelium)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma
CFB complement factor B
CFD complement factor D (adipsin)
CFH complement factor H
CFP complement factor properdin
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CIITA class II, major histocompatibility complex, transactivator
CLCN2 chloride channel, voltage-sensitive 2
CLCN3 chloride channel, voltage-sensitive 3
CLCN7 chloride channel, voltage-sensitive 7
CLEC4E C-type lectin domain family 4, member E
CLEC4F C-type lectin domain family 4, member F
CLEC6A C-type lectin domain family 6, member A
CLEC7A C-type lectin domain family 7, member A
CLIC4 chloride intracellular channel 4
CLNK cytokine-dependent hematopoietic cell linker
CMKLR1 chemerin chemokine-like receptor 1
CNN2 calponin 2
CNPY3 canopy FGF signaling regulator 3
CNR2 cannabinoid receptor 2 (macrophage)
COL1A1 collagen, type I, alpha 1
CORO1A coronin, actin binding protein, 1A
CPB2 carboxypeptidase B2 (plasma)
CPN1 carboxypeptidase N, polypeptide 1
CREB3L3 cAMP responsive element binding protein 3-like 3
CRP C-reactive protein, pentraxin-related
CRY2 cryptochrome circadian clock 2
CSF1 colony stimulating factor 1 (macrophage)
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CSF3 colony stimulating factor 3 (granulocyte)
CSF3R colony stimulating factor 3 receptor (granulocyte)
CSPG4 chondroitin sulfate proteoglycan 4
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSC cathepsin C
CTSK cathepsin K
CTSV cathepsin V
CTTN cortactin
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL6 chemokine (C-X-C motif) ligand 6
CXCR2 chemokine (C-X-C motif) receptor 2
CXCR3 chemokine (C-X-C motif) receptor 3
CXCR4 chemokine (C-X-C motif) receptor 4
CYBA cytochrome b-245, alpha polypeptide
CYBB cytochrome b-245, beta polypeptide
DCSTAMP dendrocyte expressed seven transmembrane protein
DDIT3 DNA-damage-inducible transcript 3
DOCK2 dedicator of cytokinesis 2
DOCK3 dedicator of cytokinesis 3
DTNBP1 dystrobrevin binding protein 1
DUSP1 dual specificity phosphatase 1
DUSP2 dual specificity phosphatase 2
DUSP4 dual specificity phosphatase 4
EDIL3 EGF-like repeats and discoidin I-like domains 3
EGR1 early growth response 1
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4
ELANE elastase, neutrophil expressed
ELF4 E74-like factor 4 (ets domain transcription factor)
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
ERO1L ERO1-like (S. cerevisiae)
ESR1 estrogen receptor 1
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
F3 coagulation factor III (thromboplastin, tissue factor)
FADS2 fatty acid desaturase 2
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FASTK Fas-activated serine/threonine kinase
FBLIM1 filamin binding LIM protein 1
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23)
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FES FES proto-oncogene, tyrosine kinase
FFAR2 free fatty acid receptor 2
FGA fibrinogen alpha chain
FGFR3 fibroblast growth factor receptor 3
FGG fibrinogen gamma chain
FLOT1 flotillin 1
FLT1 fms-related tyrosine kinase 1
FLT3 fms-related tyrosine kinase 3
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSL2 FOS-like antigen 2
FOXQ1 forkhead box Q1
FPR1 formyl peptide receptor 1
FPR2 formyl peptide receptor 2
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
FYN FYN proto-oncogene, Src family tyrosine kinase
G6PC3 glucose 6 phosphatase, catalytic, 3
GADD45G growth arrest and DNA-damage-inducible, gamma
GALC galactosylceramidase
GBP3 guanylate binding protein 3
GBP5 guanylate binding protein 5
GFI1 growth factor independent 1 transcription repressor
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GJA1 gap junction protein, alpha 1, 43kDa
GLB1 galactosidase, beta 1
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
GPR132 G protein-coupled receptor 132
GPR21 G protein-coupled receptor 21
GPR55 G protein-coupled receptor 55
GPR65 G protein-coupled receptor 65
GPR68 G protein-coupled receptor 68
GRN granulin
GSN gelsolin
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HCK HCK proto-oncogene, Src family tyrosine kinase
HCST hematopoietic cell signal transducer
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-G major histocompatibility complex, class I, G
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HPS1 Hermansky-Pudlak syndrome 1
HRG histidine-rich glycoprotein
HSPB1 heat shock 27kDa protein 1
HVCN1 hydrogen voltage gated channel 1
ICAM1 intercellular adhesion molecule 1
ICOS inducible T-cell co-stimulator
IDUA iduronidase, alpha-L-
IER3 immediate early response 3
IFNAR1 interferon (alpha, beta and omega) receptor 1
IFNAR2 interferon (alpha, beta and omega) receptor 2
IFNB1 interferon, beta 1, fibroblast
IFNG interferon, gamma
IFNGR1 interferon gamma receptor 1
IGHM immunoglobulin heavy constant mu
IL10 interleukin 10
IL12A interleukin 12A
IL12B interleukin 12B
IL12RB2 interleukin 12 receptor, beta 2
IL13 interleukin 13
IL13RA2 interleukin 13 receptor, alpha 2
IL15 interleukin 15
IL15RA interleukin 15 receptor, alpha
IL17RA interleukin 17 receptor A
IL18 interleukin 18
IL18R1 interleukin 18 receptor 1
IL1B interleukin 1, beta
IL1R1 interleukin 1 receptor, type I
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
IL21R interleukin 21 receptor
IL23A interleukin 23, alpha subunit p19
IL2RG interleukin 2 receptor, gamma
IL31RA interleukin 31 receptor A
IL4R interleukin 4 receptor
IL6 interleukin 6
IL6R interleukin 6 receptor
IL6ST interleukin 6 signal transducer
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
IRAK2 interleukin-1 receptor-associated kinase 2
IRAK3 interleukin-1 receptor-associated kinase 3
IRAK4 interleukin-1 receptor-associated kinase 4
IRF1 interferon regulatory factor 1
IRS1 insulin receptor substrate 1
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGAD integrin, alpha D
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
JCHAIN joining chain of multimeric IgA and IgM
JDP2 Jun dimerization protein 2
JMJD6 jumonji domain containing 6
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLRK1 killer cell lectin-like receptor subfamily K, member 1
KMT2E lysine (K)-specific methyltransferase 2E
LAG3 lymphocyte-activation gene 3
LBP lipopolysaccharide binding protein
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
LECT1 leukocyte cell derived chemotaxin 1
LEP leptin
LGALS3 lectin, galactoside-binding, soluble, 3
LGMN legumain
LIF leukemia inhibitory factor
LIMD1 LIM domains containing 1
LITAF lipopolysaccharide-induced TNF factor
LRRK1 leucine-rich repeat kinase 1
LSP1 lymphocyte-specific protein 1
LTA lymphotoxin alpha
LTB4R leukotriene B4 receptor
LTB4R2 leukotriene B4 receptor 2
LY96 lymphocyte antigen 96
LYN LYN proto-oncogene, Src family tyrosine kinase
LYST lysosomal trafficking regulator
MAN2C1 mannosidase, alpha, class 2C, member 1
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MARCKSL1 MARCKS-like 1
MARCO macrophage receptor with collagenous structure
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
MASP2 mannan-binding lectin serine peptidase 2
MAVS mitochondrial antiviral signaling protein
MB21D1 Mab-21 domain containing 1
MCAM melanoma cell adhesion molecule
MCOLN1 mucolipin 1
MDK midkine (neurite growth-promoting factor 2)
MEFV Mediterranean fever
MEPE matrix extracellular phosphoglycoprotein
MFGE8 milk fat globule-EGF factor 8 protein
MIR223 microRNA 223
MITF microphthalmia-associated transcription factor
MLKL mixed lineage kinase domain-like
MMP12 matrix metallopeptidase 12
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP28 matrix metallopeptidase 28
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
MPO myeloperoxidase
MPP1 membrane protein, palmitoylated 1, 55kDa
MPZ myelin protein zero
MRC1 mannose receptor, C type 1
MSR1 macrophage scavenger receptor 1
MST1 macrophage stimulating 1
MST1R macrophage stimulating 1 receptor
MUC5B mucin 5B, oligomeric mucus/gel-forming
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYD88 myeloid differentiation primary response 88
MYO1F myosin IF
MYO9B myosin IXB
NBR1 neighbor of BRCA1 gene 1
NCEH1 neutral cholesterol ester hydrolase 1
NCF1 neutrophil cytosolic factor 1
NCF4 neutrophil cytosolic factor 4, 40kDa
NCKAP1L NCK-associated protein 1-like
NCR1 natural cytotoxicity triggering receptor 1
NEIL3 nei endonuclease VIII-like 3 (E. coli)
NFE2L2 nuclear factor, erythroid 2-like 2
NFIL3 nuclear factor, interleukin 3 regulated
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NFKBID nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta
NINJ1 ninjurin 1
NLRC4 NLR family, CARD domain containing 4
NLRP1 NLR family, pyrin domain containing 1
NLRP12 NLR family, pyrin domain containing 12
NLRP3 NLR family, pyrin domain containing 3
NLRX1 NLR family member X1
NOD1 nucleotide-binding oligomerization domain containing 1
NOD2 nucleotide-binding oligomerization domain containing 2
NOS1 nitric oxide synthase 1 (neuronal)
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NOV nephroblastoma overexpressed
NPC1 Niemann-Pick disease, type C1
NPC2 Niemann-Pick disease, type C2
NPR1 natriuretic peptide receptor 1
NPY1R neuropeptide Y receptor Y1
NUP98 nucleoporin 98kDa
OCA2 oculocutaneous albinism II
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PADI4 peptidyl arginine deiminase, type IV
PARP1 poly (ADP-ribose) polymerase 1
PCTP phosphatidylcholine transfer protein
PDE4B phosphodiesterase 4B, cAMP-specific
PDE4D phosphodiesterase 4D, cAMP-specific
PELI3 pellino E3 ubiquitin protein ligase family member 3
PGAP3 post-GPI attachment to proteins 3
PGLYRP1 peptidoglycan recognition protein 1
PGLYRP2 peptidoglycan recognition protein 2
PHEX phosphate regulating endopeptidase homolog, X-linked
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PILRA paired immunoglobin-like type 2 receptor alpha
PLA2G10 phospholipase A2, group X
PLA2G15 phospholipase A2, group XV
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLA2G5 phospholipase A2, group V
PLAC8 placenta-specific 8
PLAT plasminogen activator, tissue
PLAU plasminogen activator, urokinase
PLAUR plasminogen activator, urokinase receptor
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLD2 phospholipase D2
PLEC plectin
PLG plasminogen
PON2 paraoxonase 2
PPT1 palmitoyl-protein thioesterase 1
PRAM1 PML-RARA regulated adaptor molecule 1
PRDX1 peroxiredoxin 1
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
PRF1 perforin 1 (pore forming protein)
PRKCD protein kinase C, delta
PRKCE protein kinase C, epsilon
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PSAP prosaposin
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTGES prostaglandin E synthase
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK2B protein tyrosine kinase 2 beta
PTN pleiotrophin
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTPRC protein tyrosine phosphatase, receptor type, C
PTPRE protein tyrosine phosphatase, receptor type, E
PTX3 pentraxin 3, long
PYCARD PYD and CARD domain containing
RAB27A RAB27A, member RAS oncogene family
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RAG1 recombination activating gene 1
RAG2 recombination activating gene 2
RAP1A RAP1A, member of RAS oncogene family
RASA4 RAS p21 protein activator 4
RASGRP4 RAS guanyl releasing protein 4
RC3H2 ring finger and CCCH-type domains 2
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RFX5 regulatory factor X, 5 (influences HLA class II expression)
RHBDD3 rhomboid domain containing 3
RIPK2 receptor-interacting serine-threonine kinase 2
RNF19B ring finger protein 19B
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
RORA RAR-related orphan receptor A
S100A4 S100 calcium binding protein A4
S100A9 S100 calcium binding protein A9
S1PR5 sphingosine-1-phosphate receptor 5
SARM1 sterile alpha and TIR motif containing 1
SBNO2 strawberry notch homolog 2 (Drosophila)
SCARF1 scavenger receptor class F, member 1
SELE selectin E
SELK selenoprotein K
SELL selectin L
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SELPLG selectin P ligand
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SERTAD2 SERTA domain containing 2
SFTPD surfactant protein D
SGMS2 sphingomyelin synthase 2
SH2D1A SH2 domain containing 1A
SH2D1B SH2 domain containing 1B
SH3BP2 SH3-domain binding protein 2
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin
SIGLEC9 sialic acid binding Ig-like lectin 9
SIRPA signal-regulatory protein alpha
SLAMF1 signaling lymphocytic activation molecule family member 1
SLAMF6 SLAM family member 6
SLAMF7 SLAM family member 7
SLAMF8 SLAM family member 8
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1
SLC4A2 solute carrier family 4 (anion exchanger), member 2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLPI secretory leukocyte peptidase inhibitor
SMAD3 SMAD family member 3
SOCS1 suppressor of cytokine signaling 1
SOCS2 suppressor of cytokine signaling 2
SPIC Spi-C transcription factor (Spi-1/PU.1 related)
SPP1 secreted phosphoprotein 1
SQSTM1 sequestosome 1
SSTR4 somatostatin receptor 4
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT4 signal transducer and activator of transcription 4
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
STX11 syntaxin 11
SUCO SUN domain containing ossification factor
SYK spleen tyrosine kinase
TANK TRAF family member-associated NFKB activator
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TAPBP TAP binding protein (tapasin)
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1
TBK1 TANK-binding kinase 1
TBX21 T-box 21
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
TFF2 trefoil factor 2
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFB2 transforming growth factor, beta 2
TGM2 transglutaminase 2
THRA thyroid hormone receptor, alpha
THRB thyroid hormone receptor, beta
TIA1 TIA1 cytotoxic granule-associated RNA binding protein
TICAM1 toll-like receptor adaptor molecule 1
TIMD4 T-cell immunoglobulin and mucin domain containing 4
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein
TLR1 toll-like receptor 1
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TLR5 toll-like receptor 5
TLR6 toll-like receptor 6
TLR7 toll-like receptor 7
TLR9 toll-like receptor 9
TMEM173 transmembrane protein 173
TNF tumor necrosis factor
TNFAIP8L2 tumor necrosis factor, alpha-induced protein 8-like 2
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNIP1 TNFAIP3 interacting protein 1
TNIP2 TNFAIP3 interacting protein 2
TOB2 transducer of ERBB2, 2
TPSAB1 tryptase alpha/beta 1
TRAF3IP2 TRAF3 interacting protein 2
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TRPV2 transient receptor potential cation channel, subfamily V, member 2
TXNIP thioredoxin interacting protein
TYK2 tyrosine kinase 2
TYROBP TYRO protein tyrosine kinase binding protein
UBE2N ubiquitin-conjugating enzyme E2N
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UNC13D unc-13 homolog D (C. elegans)
UNC93B1 unc-93 homolog B1 (C. elegans)
VAV1 vav 1 guanine nucleotide exchange factor
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
WAS Wiskott-Aldrich syndrome
WDR1 WD repeat domain 1
WWOX WW domain containing oxidoreductase
XPA xeroderma pigmentosum, complementation group A
ZFP36 ZFP36 ring finger protein