abnormal incidence of induced tumors Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description aberration from the normal frequency of tumor incidence induced by a carcinogen, mutagen or virus (Mammalian Phenotype Ontology, MP_0013151)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0013151
Similar Terms
Downloads & Tools

Genes

177 gene mutations causing the abnormal incidence of induced tumors phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AFP alpha-fetoprotein
AGTR2 angiotensin II receptor, type 2
AHR aryl hydrocarbon receptor
AHRR aryl-hydrocarbon receptor repressor
APC adenomatous polyposis coli
AR androgen receptor
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
ASIP agouti signaling protein
ATG4C autophagy related 4C, cysteine peptidase
B3GNT6 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6
BIN3 bridging integrator 3
BLM Bloom syndrome, RecQ helicase-like
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
BUB3 BUB3 mitotic checkpoint protein
CACFD1 calcium channel flower domain containing 1
CASC1 cancer susceptibility candidate 1
CAT catalase
CAV1 caveolin 1, caveolae protein, 22kDa
CCL13 chemokine (C-C motif) ligand 13
CCNG1 cyclin G1
CD151 CD151 molecule (Raph blood group)
CD226 CD226 molecule
CD34 CD34 molecule
CDC25A cell division cycle 25A
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CHEK2 checkpoint kinase 2
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
COPS6 COP9 signalosome subunit 6
CUL9 cullin 9
CYGB cytoglobin
CYLD cylindromatosis (turban tumor syndrome)
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DDB2 damage-specific DNA binding protein 2, 48kDa
DEK DEK proto-oncogene
DMTF1 cyclin D binding myb-like transcription factor 1
EGR1 early growth response 1
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
EPHA2 EPH receptor A2
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
ERCC2 excision repair cross-complementation group 2
ERCC6 excision repair cross-complementation group 6
ERCC8 excision repair cross-complementation group 8
ERRFI1 ERBB receptor feedback inhibitor 1
FGF22 fibroblast growth factor 22
FHIT fragile histidine triad
FLCN folliculin
FOLR1 folate receptor 1 (adult)
FOXM1 forkhead box M1
FOXN1 forkhead box N1
FPR2 formyl peptide receptor 2
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GADD45A growth arrest and DNA-damage-inducible, alpha
GAST gastrin
HCST hematopoietic cell signal transducer
HINT1 histidine triad nucleotide binding protein 1
HIPK1 homeodomain interacting protein kinase 1
HMGN1 high mobility group nucleosome binding domain 1
HRAS Harvey rat sarcoma viral oncogene homolog
IER3 immediate early response 3
IFNAR1 interferon (alpha, beta and omega) receptor 1
IFNAR2 interferon (alpha, beta and omega) receptor 2
IL10 interleukin 10
IL12A interleukin 12A
IL12B interleukin 12B
IL1R1 interleukin 1 receptor, type I
IL22 interleukin 22
IL22RA2 interleukin 22 receptor, alpha 2
IL23A interleukin 23, alpha subunit p19
IL6 interleukin 6
IL6R interleukin 6 receptor
IP6K2 inositol hexakisphosphate kinase 2
IRF1 interferon regulatory factor 1
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
KLF10 Kruppel-like factor 10
KRT10 keratin 10, type I
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2
LYST lysosomal trafficking regulator
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAPK8 mitogen-activated protein kinase 8
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MMP1 matrix metallopeptidase 1
MMP11 matrix metallopeptidase 11
MMP19 matrix metallopeptidase 19
MPG N-methylpurine-DNA glycosylase
MSH2 mutS homolog 2
MTF1 metal-regulatory transcription factor 1
MXI1 MAX interactor 1, dimerization protein
MYD88 myeloid differentiation primary response 88
NBN nibrin
NCOA3 nuclear receptor coactivator 3
NDRG1 N-myc downstream regulated 1
NEU3 sialidase 3 (membrane sialidase)
NFE2 nuclear factor, erythroid 2
NFE2L2 nuclear factor, erythroid 2-like 2
NIT1 nitrilase 1
NLRP12 NLR family, pyrin domain containing 12
NLRP6 NLR family, pyrin domain containing 6
PAQR3 progestin and adipoQ receptor family member III
PER2 period circadian clock 2
PGR progesterone receptor
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLCE1 phospholipase C, epsilon 1
PLCL1 phospholipase C-like 1
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
POLG polymerase (DNA directed), gamma
POLH polymerase (DNA directed), eta
PPARD peroxisome proliferator-activated receptor delta
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PRF1 perforin 1 (pore forming protein)
PRKCH protein kinase C, eta
PTCH1 patched 1
PTEN phosphatase and tensin homolog
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTP4A3 protein tyrosine phosphatase type IVA, member 3
PTPRJ protein tyrosine phosphatase, receptor type, J
PTPRT protein tyrosine phosphatase, receptor type, T
PVR poliovirus receptor
RAE1 ribonucleic acid export 1
RALGAPA2 Ral GTPase activating protein, alpha subunit 2 (catalytic)
RALGDS ral guanine nucleotide dissociation stimulator
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RFWD2 ring finger and WD repeat domain 2, E3 ubiquitin protein ligase
RGPD1 RANBP2-like and GRIP domain containing 1
RHOB ras homolog family member B
SAMD9L sterile alpha motif domain containing 9-like
SF1 splicing factor 1
SKI SKI proto-oncogene
SKIL SKI-like proto-oncogene
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SPP1 secreted phosphoprotein 1
STAG1 stromal antigen 1
STK11 serine/threonine kinase 11
TERC telomerase RNA component
TERT telomerase reverse transcriptase
TGFBI transforming growth factor, beta-induced, 68kDa
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THBS2 thrombospondin 2
TIAM1 T-cell lymphoma invasion and metastasis 1
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TP53 tumor protein p53
TP53BP2 tumor protein p53 binding protein 2
TP53INP1 tumor protein p53 inducible nuclear protein 1
TP73 tumor protein p73
TREM1 triggering receptor expressed on myeloid cells 1
TREX2 three prime repair exonuclease 2
TRIM27 tripartite motif containing 27
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSC1 tuberous sclerosis 1
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats
UIMC1 ubiquitin interaction motif containing 1
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
WIF1 WNT inhibitory factor 1
WWOX WW domain containing oxidoreductase
XPA xeroderma pigmentosum, complementation group A
XPC xeroderma pigmentosum, complementation group C