abnormal immune system organ morphology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any structural anomaly of lymphoid organs (Mammalian Phenotype Ontology, MP_0002722)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0002722
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Genes

892 gene mutations causing the abnormal immune system organ morphology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCC10 ATP-binding cassette, sub-family C (CFTR/MRP), member 10
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACKR3 atypical chemokine receptor 3
ACKR4 atypical chemokine receptor 4
ACVR2B activin A receptor, type IIB
ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6
ADD2 adducin 2 (beta)
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
ADM adrenomedullin
ADRM1 adhesion regulating molecule 1
AFF1 AF4/FMR2 family, member 1
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2
AGR2 anterior gradient 2
AHR aryl hydrocarbon receptor
AHSP alpha hemoglobin stabilizing protein
AIF1 allograft inflammatory factor 1
AIRE autoimmune regulator
AKAP12 A kinase (PRKA) anchor protein 12
AKAP13 A kinase (PRKA) anchor protein 13
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
ALOX15 arachidonate 15-lipoxygenase
ALOX5 arachidonate 5-lipoxygenase
ALPL alkaline phosphatase, liver/bone/kidney
AMER1 APC membrane recruitment protein 1
ANGPTL4 angiopoietin-like 4
ANK1 ankyrin 1, erythrocytic
AP2B1 adaptor-related protein complex 2, beta 1 subunit
APC adenomatous polyposis coli
APCS amyloid P component, serum
APEX2 APEX nuclease (apurinic/apyrimidinic endonuclease) 2
APOE apolipoprotein E
AQP3 aquaporin 3 (Gill blood group)
ARAF A-Raf proto-oncogene, serine/threonine kinase
ARHGAP1 Rho GTPase activating protein 1
ARHGAP5 Rho GTPase activating protein 5
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ARID4A AT rich interactive domain 4A (RBP1-like)
ARID5B AT rich interactive domain 5B (MRF1-like)
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
ARMC4 armadillo repeat containing 4
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ASB1 ankyrin repeat and SOCS box containing 1
ASL argininosuccinate lyase
ASXL1 additional sex combs like transcriptional regulator 1
ATCAY ataxia, cerebellar, Cayman type
ATG5 autophagy related 5
ATM ATM serine/threonine kinase
ATMIN ATM interactor
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide
ATR ATR serine/threonine kinase
AZGP1 alpha-2-glycoprotein 1, zinc-binding
B3GNT5 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
BAD BCL2-associated agonist of cell death
BAG3 BCL2-associated athanogene 3
BAG4 BCL2-associated athanogene 4
BANK1 B-cell scaffold protein with ankyrin repeats 1
BAX BCL2-associated X protein
BBC3 BCL2 binding component 3
BCL10 B-cell CLL/lymphoma 10
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BCL2 B-cell CLL/lymphoma 2
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BCL3 B-cell CLL/lymphoma 3
BCL6 B-cell CLL/lymphoma 6
BCO2 beta-carotene oxygenase 2
BECN1 beclin 1, autophagy related
BHLHE40 basic helix-loop-helix family, member e40
BIN3 bridging integrator 3
BIRC3 baculoviral IAP repeat containing 3
BLNK B-cell linker
BMF Bcl2 modifying factor
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
BOK BCL2-related ovarian killer
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA2 breast cancer 2, early onset
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
BST2 bone marrow stromal cell antigen 2
BTK Bruton agammaglobulinemia tyrosine kinase
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
C1ORF127 chromosome 1 open reading frame 127
C3 complement component 3
C4A complement component 4A (Rodgers blood group)
C5AR1 complement component 5a receptor 1
C6ORF25 chromosome 6 open reading frame 25
CA6 carbonic anhydrase VI
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CACNB4 calcium channel, voltage-dependent, beta 4 subunit
CACYBP calcyclin binding protein
CALCRL calcitonin receptor-like
CARD11 caspase recruitment domain family, member 11
CARM1 coactivator-associated arginine methyltransferase 1
CASP3 caspase 3, apoptosis-related cysteine peptidase
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CBFB core-binding factor, beta subunit
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CBX4 chromobox homolog 4
CCDC151 coiled-coil domain containing 151
CCDC39 coiled-coil domain containing 39
CCL25 chemokine (C-C motif) ligand 25
CCNB2 cyclin B2
CCND3 cyclin D3
CCNE1 cyclin E1
CCR2 chemokine (C-C motif) receptor 2
CCR6 chemokine (C-C motif) receptor 6
CCR7 chemokine (C-C motif) receptor 7
CCR9 chemokine (C-C motif) receptor 9
CCRL2 chemokine (C-C motif) receptor-like 2
CD19 CD19 molecule
CD200 CD200 molecule
CD22 CD22 molecule
CD247 CD247 molecule
CD28 CD28 molecule
CD2AP CD2-associated protein
CD34 CD34 molecule
CD37 CD37 molecule
CD3E CD3e molecule, epsilon (CD3-TCR complex)
CD3G CD3g molecule, gamma (CD3-TCR complex)
CD4 CD4 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CD47 CD47 molecule
CD5L CD5 molecule-like
CD7 CD7 molecule
CD72 CD72 molecule
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CD79A CD79a molecule, immunoglobulin-associated alpha
CD79B CD79b molecule, immunoglobulin-associated beta
CD84 CD84 molecule
CD86 CD86 molecule
CD8B CD8b molecule
CDH17 cadherin 17, LI cadherin (liver-intestine)
CDK6 cyclin-dependent kinase 6
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon
CEP290 centrosomal protein 290kDa
CFC1 cripto, FRL-1, cryptic family 1
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHD2 chromodomain helicase DNA binding protein 2
CHD7 chromodomain helicase DNA binding protein 7
CHRD chordin
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
CIDEB cell death-inducing DFFA-like effector b
CIITA class II, major histocompatibility complex, transactivator
CISH cytokine inducible SH2-containing protein
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CLEC10A C-type lectin domain family 10, member A
CLEC4D C-type lectin domain family 4, member D
COL10A1 collagen, type X, alpha 1
COMMD3-BMI1 COMMD3-BMI1 readthrough
CORO1A coronin, actin binding protein, 1A
CP ceruloplasmin (ferroxidase)
CR2 complement component (3d/Epstein Barr virus) receptor 2
CREBBP CREB binding protein
CRH corticotropin releasing hormone
CRIP3 cysteine-rich protein 3
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CSF1 colony stimulating factor 1 (macrophage)
CSF1R colony stimulating factor 1 receptor
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CTC1 CTS telomere maintenance complex component 1
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSA cathepsin A
CTSD cathepsin D
CTSG cathepsin G
CTSV cathepsin V
CUX1 cut-like homeobox 1
CXCL13 chemokine (C-X-C motif) ligand 13
CXCR2 chemokine (C-X-C motif) receptor 2
CXCR4 chemokine (C-X-C motif) receptor 4
CXCR5 chemokine (C-X-C motif) receptor 5
CYCS cytochrome c, somatic
CYLD cylindromatosis (turban tumor syndrome)
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
CYS1 cystin 1
CYTIP cytohesin 1 interacting protein
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila)
DAD1 defender against cell death 1
DAW1 dynein assembly factor with WDR repeat domains 1
DBNL drebrin-like
DCC DCC netrin 1 receptor
DCK deoxycytidine kinase
DCLRE1C DNA cross-link repair 1C
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DEDD death effector domain containing
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DFNB31 deafness, autosomal recessive 31
DHRS7B dehydrogenase/reductase (SDR family) member 7B
DIAPH1 diaphanous-related formin 1
DIDO1 death inducer-obliterator 1
DKC1 dyskeratosis congenita 1, dyskerin
DLK1 delta-like 1 homolog (Drosophila)
DMTF1 cyclin D binding myb-like transcription factor 1
DNAH11 dynein, axonemal, heavy chain 11
DNAH5 dynein, axonemal, heavy chain 5
DNAI1 dynein, axonemal, intermediate chain 1
DNASE1 deoxyribonuclease I
DNASE2 deoxyribonuclease II, lysosomal
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DOCK2 dedicator of cytokinesis 2
DOCK8 dedicator of cytokinesis 8
DRC1 dynein regulatory complex subunit 1
DRD2 dopamine receptor D2
DSG4 desmoglein 4
DTX1 deltex 1, E3 ubiquitin ligase
DUSP6 dual specificity phosphatase 6
DYX1C1 dyslexia susceptibility 1 candidate 1
E2F1 E2F transcription factor 1
E2F2 E2F transcription factor 2
E2F4 E2F transcription factor 4, p107/p130-binding
ECE1 endothelin converting enzyme 1
EDNRA endothelin receptor type A
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EFNB2 ephrin-B2
EGLN1 egl-9 family hypoxia-inducible factor 1
EGR1 early growth response 1
ELAVL1 ELAV like RNA binding protein 1
ELF4 E74-like factor 4 (ets domain transcription factor)
ELK4 ELK4, ETS-domain protein (SRF accessory protein 1)
ELMOD1 ELMO/CED-12 domain containing 1
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
EP300 E1A binding protein p300
EPAS1 endothelial PAS domain protein 1
EPB41 erythrocyte membrane protein band 4.1
EPB42 erythrocyte membrane protein band 4.2
EPGN epithelial mitogen
EPO erythropoietin
EPOR erythropoietin receptor
EPS15 epidermal growth factor receptor pathway substrate 15
ERAP1 endoplasmic reticulum aminopeptidase 1
ERCC1 excision repair cross-complementation group 1
ERCC2 excision repair cross-complementation group 2
ERCC5 excision repair cross-complementation group 5
ERRFI1 ERBB receptor feedback inhibitor 1
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
ESRRA estrogen-related receptor alpha
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
EWSR1 EWS RNA-binding protein 1
EXOC6 exocyst complex component 6
EYA1 EYA transcriptional coactivator and phosphatase 1
F2R coagulation factor II (thrombin) receptor
F9 coagulation factor IX
FADS2 fatty acid desaturase 2
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FBLN1 fibulin 1
FBXL5 F-box and leucine-rich repeat protein 5
FCAMR Fc receptor, IgA, IgM, high affinity
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FCMR Fc fragment of IgM receptor
FECH ferrochelatase
FEN1 flap structure-specific endonuclease 1
FES FES proto-oncogene, tyrosine kinase
FGF10 fibroblast growth factor 10
FGF23 fibroblast growth factor 23
FGF7 fibroblast growth factor 7
FGFR2 fibroblast growth factor receptor 2
FIG4 FIG4 phosphoinositide 5-phosphatase
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FLT3 fms-related tyrosine kinase 3
FLT3LG fms-related tyrosine kinase 3 ligand
FLVCR1 feline leukemia virus subgroup C cellular receptor 1
FNIP1 folliculin interacting protein 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXC2 forkhead box C2
FOXN1 forkhead box N1
FOXO3 forkhead box O3
FOXP3 forkhead box P3
FPR2 formyl peptide receptor 2
FSHR follicle stimulating hormone receptor
FUS FUS RNA binding protein
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
FXR1 fragile X mental retardation, autosomal homolog 1
FYB FYN binding protein
FZD9 frizzled class receptor 9
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GABPB2 GA binding protein transcription factor, beta subunit 2
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1
GAPT GRB2-binding adaptor protein, transmembrane
GATA1 GATA binding protein 1 (globin transcription factor 1)
GATA3 GATA binding protein 3
GBA glucosidase, beta, acid
GCSAM germinal center-associated, signaling and motility
GDF1 growth differentiation factor 1
GDF11 growth differentiation factor 11
GDNF glial cell derived neurotrophic factor
GFI1 growth factor independent 1 transcription repressor
GFRA1 GDNF family receptor alpha 1
GGT1 gamma-glutamyltransferase 1
GHR growth hormone receptor
GIMAP1-GIMAP5 GIMAP1-GIMAP5 readthrough
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GLB1 galactosidase, beta 1
GLMP glycosylated lysosomal membrane protein
GLRA1 glycine receptor, alpha 1
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GNAS GNAS complex locus
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GON4L gon-4-like (C. elegans)
GPC3 glypican 3
GPI glucose-6-phosphate isomerase
GPR132 G protein-coupled receptor 132
GPR83 G protein-coupled receptor 83
GPX7 glutathione peroxidase 7
GRAP2 GRB2-related adaptor protein 2
GRB14 growth factor receptor-bound protein 14
GSTK1 glutathione S-transferase kappa 1
GSTZ1 glutathione S-transferase zeta 1
HAMP hepcidin antimicrobial peptide
HAVCR1 hepatitis A virus cellular receptor 1
HAX1 HCLS1 associated protein X-1
HCST hematopoietic cell signal transducer
HELLS helicase, lymphoid-specific
HFE hemochromatosis
HFE2 hemochromatosis type 2 (juvenile)
HHIP hedgehog interacting protein
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2
HK1 hexokinase 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HMGA1 high mobility group AT-hook 1
HMOX1 heme oxygenase 1
HOXA1 homeobox A1
HOXA3 homeobox A3
HOXA9 homeobox A9
HOXB4 homeobox B4
HOXB9 homeobox B9
HPGDS hematopoietic prostaglandin D synthase
HPRT1 hypoxanthine phosphoribosyltransferase 1
HR hair growth associated
HSH2D hematopoietic SH2 domain containing
HTRA2 HtrA serine peptidase 2
HYAL2 hyaluronoglucosaminidase 2
HYDIN HYDIN, axonemal central pair apparatus protein
ICOS inducible T-cell co-stimulator
ICOSLG inducible T-cell co-stimulator ligand
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IDS iduronate 2-sulfatase
IFNB1 interferon, beta 1, fibroblast
IFNG interferon, gamma
IFNGR1 interferon gamma receptor 1
IFT140 intraflagellar transport 140
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGHM immunoglobulin heavy constant mu
IGKC immunoglobulin kappa constant
IGLL1 immunoglobulin lambda-like polypeptide 1
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IKZF3 IKAROS family zinc finger 3 (Aiolos)
IL10 interleukin 10
IL10RB interleukin 10 receptor, beta
IL12RB2 interleukin 12 receptor, beta 2
IL13RA1 interleukin 13 receptor, alpha 1
IL15 interleukin 15
IL15RA interleukin 15 receptor, alpha
IL1RL2 interleukin 1 receptor-like 2
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
IL21 interleukin 21
IL25 interleukin 25
IL2RA interleukin 2 receptor, alpha
IL2RB interleukin 2 receptor, beta
IL2RG interleukin 2 receptor, gamma
IL31RA interleukin 31 receptor A
IL34 interleukin 34
IL6ST interleukin 6 signal transducer
IL7 interleukin 7
IL7R interleukin 7 receptor
INCA1 inhibitor of CDK, cyclin A1 interacting protein 1
ING1 inhibitor of growth family, member 1
ING2 inhibitor of growth family, member 2
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
INVS inversin
IRAK3 interleukin-1 receptor-associated kinase 3
IREB2 iron-responsive element binding protein 2
IRF1 interferon regulatory factor 1
IRF2 interferon regulatory factor 2
IRF4 interferon regulatory factor 4
IRF8 interferon regulatory factor 8
ITFG2 integrin alpha FG-GAP repeat containing 2
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGA6 integrin, alpha 6
ITGAD integrin, alpha D
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITGB7 integrin, beta 7
ITK IL2-inducible T-cell kinase
ITPKB inositol-trisphosphate 3-kinase B
JAG2 jagged 2
JAK1 Janus kinase 1
JAK2 Janus kinase 2
JAK3 Janus kinase 3
JARID2 jumonji, AT rich interactive domain 2
JMJD6 jumonji domain containing 6
KAT6A K(lysine) acetyltransferase 6A
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
KDM8 lysine (K)-specific demethylase 8
KIAA0101 KIAA0101
KIFAP3 kinesin-associated protein 3
KISS1R KISS1 receptor
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KITLG KIT ligand
KL klotho
KLF1 Kruppel-like factor 1 (erythroid)
KLF13 Kruppel-like factor 13
KLF3 Kruppel-like factor 3 (basic)
KLHL6 kelch-like family member 6
KLRK1 killer cell lectin-like receptor subfamily K, member 1
KMT2A lysine (K)-specific methyltransferase 2A
KMT2E lysine (K)-specific methyltransferase 2E
KRT8 keratin 8, type II
LAG3 lymphocyte-activation gene 3
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LAMA2 laminin, alpha 2
LAMP2 lysosomal-associated membrane protein 2
LAT linker for activation of T cells
LAT2 linker for activation of T cells family, member 2
LAX1 lymphocyte transmembrane adaptor 1
LBR lamin B receptor
LCK LCK proto-oncogene, Src family tyrosine kinase
LCN2 lipocalin 2
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
LDHA lactate dehydrogenase A
LEFTY2 left-right determination factor 2
LEP leptin
LEPR leptin receptor
LGMN legumain
LHCGR luteinizing hormone/choriogonadotropin receptor
LIG1 ligase I, DNA, ATP-dependent
LIG4 ligase IV, DNA, ATP-dependent
LIPA lipase A, lysosomal acid, cholesterol esterase
LMNA lamin A/C
LRFN2 leucine rich repeat and fibronectin type III domain containing 2
LRP2 low density lipoprotein receptor-related protein 2
LTA lymphotoxin alpha
LTB lymphotoxin beta (TNF superfamily, member 3)
LTBP4 latent transforming growth factor beta binding protein 4
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3)
LTF lactotransferrin
LYN LYN proto-oncogene, Src family tyrosine kinase
LYZ lysozyme
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MALT1 MALT1 paracaspase
MAML1 mastermind-like 1 (Drosophila)
MAN2A1 mannosidase, alpha, class 2A, member 1
MAN2B1 mannosidase, alpha, class 2B, member 1
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MARCO macrophage receptor with collagenous structure
MARK2 MAP/microtubule affinity-regulating kinase 2
MARVELD2 MARVEL domain containing 2
MAVS mitochondrial antiviral signaling protein
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
MCM2 minichromosome maintenance complex component 2
MCM4 minichromosome maintenance complex component 4
MDC1 mediator of DNA-damage checkpoint 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MEFV Mediterranean fever
MEGF8 multiple EGF-like-domains 8
MERTK MER proto-oncogene, tyrosine kinase
MFGE8 milk fat globule-EGF factor 8 protein
MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
MFSD8 major facilitator superfamily domain containing 8
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MIR144 microRNA 144
MIR155 microRNA 155
MIR451A microRNA 451a
MITF microphthalmia-associated transcription factor
MKS1 Meckel syndrome, type 1
MORF4L1 mortality factor 4 like 1
MPL MPL proto-oncogene, thrombopoietin receptor
MPZL3 myelin protein zero-like 3
MSI2 musashi RNA-binding protein 2
MSMB microseminoprotein, beta-
MST1R macrophage stimulating 1 receptor
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MTSS1 metastasis suppressor 1
MTUS1 microtubule associated tumor suppressor 1
MUC2 mucin 2, oligomeric mucus/gel-forming
MXI1 MAX interactor 1, dimerization protein
MXRA7 matrix-remodelling associated 7
MYB v-myb avian myeloblastosis viral oncogene homolog
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
NBEAL2 neurobeachin-like 2
NBN nibrin
NCAPH2 non-SMC condensin II complex, subunit H2
NCKAP1L NCK-associated protein 1-like
NCOA3 nuclear receptor coactivator 3
NCOR1 nuclear receptor corepressor 1
NCOR2 nuclear receptor corepressor 2
NDFIP1 Nedd4 family interacting protein 1
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NEU1 sialidase 1 (lysosomal sialidase)
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NFE2 nuclear factor, erythroid 2
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NFKBID nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
NHEJ1 nonhomologous end-joining factor 1
NKX2-3 NK2 homeobox 3
NKX2-5 NK2 homeobox 5
NKX3-2 NK3 homeobox 2
NLK nemo-like kinase
NLRC5 NLR family, CARD domain containing 5
NLRP12 NLR family, pyrin domain containing 12
NLRP3 NLR family, pyrin domain containing 3
NLRP6 NLR family, pyrin domain containing 6
NOD2 nucleotide-binding oligomerization domain containing 2
NODAL nodal growth differentiation factor
NOS2 nitric oxide synthase 2, inducible
NOTCH1 notch 1
NOTCH2 notch 2
NOTCH3 notch 3
NPC1 Niemann-Pick disease, type C1
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NPR2 natriuretic peptide receptor 2
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae)
NPY1R neuropeptide Y receptor Y1
NR1H4 nuclear receptor subfamily 1, group H, member 4
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
OCA2 oculocutaneous albinism II
OTUD7B OTU deubiquitinase 7B
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1
PAPPA2 pappalysin 2
PARL presenilin associated, rhomboid-like
PARP14 poly (ADP-ribose) polymerase family, member 14
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PAWR PRKC, apoptosis, WT1, regulator
PAX1 paired box 1
PAX3 paired box 3
PAX9 paired box 9
PBX1 pre-B-cell leukemia homeobox 1
PCGF2 polycomb group ring finger 2
PCGF3 polycomb group ring finger 3
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase
PCSK1 proprotein convertase subtilisin/kexin type 1
PCSK5 proprotein convertase subtilisin/kexin type 5
PDCD1 programmed cell death 1
PDCD1LG2 programmed cell death 1 ligand 2
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDPK1 3-phosphoinositide dependent protein kinase 1
PECAM1 platelet/endothelial cell adhesion molecule 1
PELI1 pellino E3 ubiquitin protein ligase 1
PFDN1 prefoldin subunit 1
PFKM phosphofructokinase, muscle
PGAP3 post-GPI attachment to proteins 3
PGM3 phosphoglucomutase 3
PHC1 polyhomeotic homolog 1 (Drosophila)
PI16 peptidase inhibitor 16
PICALM phosphatidylinositol binding clathrin assembly protein
PIK3AP1 phosphoinositide-3-kinase adaptor protein 1
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIKFYVE phosphoinositide kinase, FYVE finger containing
PIP prolactin-induced protein
PITX2 paired-like homeodomain 2
PKD2 polycystic kidney disease 2 (autosomal dominant)
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive)
PKLR pyruvate kinase, liver and RBC
PKN1 protein kinase N1
PKNOX1 PBX/knotted 1 homeobox 1
PKP3 plakophilin 3
PLA2G15 phospholipase A2, group XV
PLCD1 phospholipase C, delta 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLG plasminogen
PLXND1 plexin D1
PNP purine nucleoside phosphorylase
POLB polymerase (DNA directed), beta
POLD1 polymerase (DNA directed), delta 1, catalytic subunit
POLE polymerase (DNA directed), epsilon, catalytic subunit
POLM polymerase (DNA directed), mu
POU2AF1 POU class 2 associating factor 1
PPIA peptidylprolyl isomerase A (cyclophilin A)
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme
PPP5C protein phosphatase 5, catalytic subunit
PPT1 palmitoyl-protein thioesterase 1
PPT2 palmitoyl-protein thioesterase 2
PRDX1 peroxiredoxin 1
PRDX2 peroxiredoxin 2
PREP prolyl endopeptidase
PRF1 perforin 1 (pore forming protein)
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit
PRKCD protein kinase C, delta
PRKCH protein kinase C, eta
PRKCQ protein kinase C, theta
PRKCZ protein kinase C, zeta
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRKG1 protein kinase, cGMP-dependent, type I
PRNP prion protein
PROX1 prospero homeobox 1
PRSS16 protease, serine, 16 (thymus)
PSAP prosaposin
PSIP1 PC4 and SFRS1 interacting protein 1
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
PTCH2 patched 2
PTCRA pre T-cell antigen receptor alpha
PTEN phosphatase and tensin homolog
PTF1A pancreas specific transcription factor, 1a
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTP4A2 protein tyrosine phosphatase type IVA, member 2
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTPRC protein tyrosine phosphatase, receptor type, C
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
PTPRJ protein tyrosine phosphatase, receptor type, J
PTTG1 pituitary tumor-transforming 1
PURA purine-rich element binding protein A
PYCARD PYD and CARD domain containing
RAD50 RAD50 homolog (S. cerevisiae)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RAG1 recombination activating gene 1
RAG2 recombination activating gene 2
RAMP2 receptor (G protein-coupled) activity modifying protein 2
RAPGEF6 Rap guanine nucleotide exchange factor (GEF) 6
RASA3 RAS p21 protein activator 3
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RASSF5 Ras association (RalGDS/AF-6) domain family member 5
RBL1 retinoblastoma-like 1
RC3H1 ring finger and CCCH-type domains 1
RECQL4 RecQ protein-like 4
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
REV1 REV1, polymerase (DNA directed)
RFTN1 raftlin, lipid raft linker 1
RFX5 regulatory factor X, 5 (influences HLA class II expression)
RGS1 regulator of G-protein signaling 1
RGS13 regulator of G-protein signaling 13
RGS3 regulator of G-protein signaling 3
RHBDF1 rhomboid 5 homolog 1 (Drosophila)
RHOH ras homolog family member H
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RIPPLY3 ripply transcriptional repressor 3
RLTPR RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
RNF168 ring finger protein 168, E3 ubiquitin protein ligase
RNF8 ring finger protein 8, E3 ubiquitin protein ligase
RORA RAR-related orphan receptor A
RORC RAR-related orphan receptor C
RPL22 ribosomal protein L22
RPL27A ribosomal protein L27a
RRAS2 related RAS viral (r-ras) oncogene homolog 2
RRM2B ribonucleotide reductase M2 B (TP53 inducible)
RUNX1 runt-related transcription factor 1
RUNX2 runt-related transcription factor 2
RUNX3 runt-related transcription factor 3
RUVBL2 RuvB-like AAA ATPase 2
S1PR2 sphingosine-1-phosphate receptor 2
S1PR3 sphingosine-1-phosphate receptor 3
SAC3D1 SAC3 domain containing 1
SAMD9L sterile alpha motif domain containing 9-like
SASH3 SAM and SH3 domain containing 3
SATB1 SATB homeobox 1
SCARF1 scavenger receptor class F, member 1
SCG5 secretogranin V
SELE selectin E
SELENBP1 selenium binding protein 1
SELL selectin L
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2
SFN stratifin
SGPL1 sphingosine-1-phosphate lyase 1
SGSH N-sulfoglucosamine sulfohydrolase
SH2B3 SH2B adaptor protein 3
SH2D1A SH2 domain containing 1A
SH2D3C SH2 domain containing 3C
SH3BP2 SH3-domain binding protein 2
SHARPIN SHANK-associated RH domain interactor
SIAE sialic acid acetylesterase
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin
SIPA1 signal-induced proliferation-associated 1
SIRT1 sirtuin 1
SIRT6 sirtuin 6
SIT1 signaling threshold regulating transmembrane adaptor 1
SIX1 SIX homeobox 1
SKIL SKI-like proto-oncogene
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
SLC22A6 solute carrier family 22 (organic anion transporter), member 6
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1
SLC46A2 solute carrier family 46, member 2
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SMAD3 SMAD family member 3
SMAD7 SMAD family member 7
SMAP1 small ArfGAP 1
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SMURF2 SMAD specific E3 ubiquitin protein ligase 2
SNAI2 snail family zinc finger 2
SNORD50A small nucleolar RNA, C/D box 50A
SNORD50B small nucleolar RNA, C/D box 50B
SNX27 sorting nexin family member 27
SOAT1 sterol O-acyltransferase 1
SOCS1 suppressor of cytokine signaling 1
SOCS3 suppressor of cytokine signaling 3
SOS1 son of sevenless homolog 1 (Drosophila)
SOX11 SRY (sex determining region Y)-box 11
SP3 Sp3 transcription factor
SP4 Sp4 transcription factor
SPHK1 sphingosine kinase 1
SPI1 Spi-1 proto-oncogene
SPIB Spi-B transcription factor (Spi-1/PU.1 related)
SPIC Spi-C transcription factor (Spi-1/PU.1 related)
SPINK1 serine peptidase inhibitor, Kazal type 1
SPPL2A signal peptide peptidase like 2A
SPTA1 spectrin, alpha, erythrocytic 1
SPTB spectrin, beta, erythrocytic
SRPX sushi-repeat containing protein, X-linked
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
STEAP3 STEAP family member 3, metalloreductase
STIM1 stromal interaction molecule 1
STK11 serine/threonine kinase 11
STK36 serine/threonine kinase 36
STK4 serine/threonine kinase 4
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
SYK spleen tyrosine kinase
T T, brachyury homolog (mouse)
TACC3 transforming, acidic coiled-coil containing protein 3
TAL1 T-cell acute lymphocytic leukemia 1
TANK TRAF family member-associated NFKB activator
TBATA thymus, brain and testes associated
TBC1D32 TBC1 domain family, member 32
TBC1D4 TBC1 domain family, member 4
TBK1 TANK-binding kinase 1
TBX1 T-box 1
TBXA2R thromboxane A2 receptor
TCF12 transcription factor 12
TCF21 transcription factor 21
TCF3 transcription factor 3
TCF7 transcription factor 7 (T-cell specific, HMG-box)
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
TDP2 tyrosyl-DNA phosphodiesterase 2
TERC telomerase RNA component
TERT telomerase reverse transcriptase
TESPA1 thymocyte expressed, positive selection associated 1
TET2 tet methylcytosine dioxygenase 2
TFR2 transferrin receptor 2
TFRC transferrin receptor
TGFB1 transforming growth factor, beta 1
TGFBI transforming growth factor, beta-induced, 68kDa
TGFBR3 transforming growth factor, beta receptor III
TGM2 transglutaminase 2
THBD thrombomodulin
THEMIS thymocyte selection associated
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TK1 thymidine kinase 1, soluble
TLR4 toll-like receptor 4
TLR7 toll-like receptor 7
TLR8 toll-like receptor 8
TLX1 T-cell leukemia homeobox 1
TMPRSS6 transmembrane protease, serine 6
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFAIP8L2 tumor necrosis factor, alpha-induced protein 8-like 2
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TNIP1 TNFAIP3 interacting protein 1
TNS2 tensin 2
TNS3 tensin 3
TOM1L2 target of myb1-like 2 (chicken)
TOMM5 translocase of outer mitochondrial membrane 5 homolog (yeast)
TOP3B topoisomerase (DNA) III beta
TOX thymocyte selection-associated high mobility group box
TP53 tumor protein p53
TP53BP1 tumor protein p53 binding protein 1
TP63 tumor protein p63
TPI1 triosephosphate isomerase 1
TPO thyroid peroxidase
TPP2 tripeptidyl peptidase II
TPX2 TPX2, microtubule-associated
TRADD TNFRSF1A-associated via death domain
TRAF1 TNF receptor-associated factor 1
TRAF2 TNF receptor-associated factor 2
TRAF3 TNF receptor-associated factor 3
TRAF3IP2 TRAF3 interacting protein 2
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRAT1 T cell receptor associated transmembrane adaptor 1
TREX1 three prime repair exonuclease 1
TRIB1 tribbles pseudokinase 1
TRIM21 tripartite motif containing 21
TRIP10 thyroid hormone receptor interactor 10
TSPAN33 tetraspanin 33
TTC7A tetratricopeptide repeat domain 7A
TWIST2 twist family bHLH transcription factor 2
TWSG1 twisted gastrulation BMP signaling modulator 1
TXNIP thioredoxin interacting protein
TYROBP TYRO protein tyrosine kinase binding protein
ULK1 unc-51 like autophagy activating kinase 1
UNC13D unc-13 homolog D (C. elegans)
UNC93B1 unc-93 homolog B1 (C. elegans)
UNG uracil-DNA glycosylase
UROS uroporphyrinogen III synthase
USP21 ubiquitin specific peptidase 21
VAV1 vav 1 guanine nucleotide exchange factor
VAV2 vav 2 guanine nucleotide exchange factor
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
WAS Wiskott-Aldrich syndrome
WIPF1 WAS/WASL interacting protein family, member 1
WNT1 wingless-type MMTV integration site family, member 1
WNT4 wingless-type MMTV integration site family, member 4
WT1 Wilms tumor 1
WWOX WW domain containing oxidoreductase
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZBTB1 zinc finger and BTB domain containing 1
ZBTB46 zinc finger and BTB domain containing 46
ZC3H12A zinc finger CCCH-type containing 12A
ZDHHC13 zinc finger, DHHC-type containing 13
ZEB1 zinc finger E-box binding homeobox 1
ZFP36 ZFP36 ring finger protein
ZFP36L2 ZFP36 ring finger protein-like 2
ZFPM1 zinc finger protein, FOG family member 1
ZIC3 Zic family member 3
ZMPSTE24 zinc metallopeptidase STE24