abnormal immune serum protein physiology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description abnormal concentration or function of circulating immune proteins (Mammalian Phenotype Ontology, MP_0002723)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0002723
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Genes

847 gene mutations causing the abnormal immune serum protein physiology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
A2M alpha-2-macroglobulin
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ACE angiotensin I converting enzyme
ACKR1 atypical chemokine receptor 1 (Duffy blood group)
ACKR4 atypical chemokine receptor 4
ACP1 acid phosphatase 1, soluble
ADAM17 ADAM metallopeptidase domain 17
ADAR adenosine deaminase, RNA-specific
ADCY9 adenylate cyclase 9
ADORA2A adenosine A2a receptor
ADORA2B adenosine A2b receptor
ADORA3 adenosine A3 receptor
ADRB2 adrenoceptor beta 2, surface
AGER advanced glycosylation end product-specific receptor
AHNAK AHNAK nucleoprotein
AHR aryl hydrocarbon receptor
AICDA activation-induced cytidine deaminase
AIM2 absent in melanoma 2
AIRE autoimmune regulator
AKAP13 A kinase (PRKA) anchor protein 13
AMPD3 adenosine monophosphate deaminase 3
ANXA5 annexin A5
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
APOE apolipoprotein E
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ARID5A AT rich interactive domain 5A (MRF1-like)
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ARRB2 arrestin, beta 2
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATF2 activating transcription factor 2
ATF3 activating transcription factor 3
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATG9A autophagy related 9A
ATM ATM serine/threonine kinase
ATP11C ATPase, class VI, type 11C
AVPR1A arginine vasopressin receptor 1A
AZI2 5-azacytidine induced 2
B2M beta-2-microglobulin
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
B3GNT5 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
B3GNT6 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
BAG4 BCL2-associated athanogene 4
BANK1 B-cell scaffold protein with ankyrin repeats 1
BATF basic leucine zipper transcription factor, ATF-like
BBS12 Bardet-Biedl syndrome 12
BBS4 Bardet-Biedl syndrome 4
BBX bobby sox homolog (Drosophila)
BCL10 B-cell CLL/lymphoma 10
BCL2L1 BCL2-like 1
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BCL2L12 BCL2-like 12 (proline rich)
BCL3 B-cell CLL/lymphoma 3
BCL6 B-cell CLL/lymphoma 6
BHLHE40 basic helix-loop-helix family, member e40
BHLHE41 basic helix-loop-helix family, member e41
BIRC2 baculoviral IAP repeat containing 2
BIRC3 baculoviral IAP repeat containing 3
BLM Bloom syndrome, RecQ helicase-like
BLNK B-cell linker
BMF Bcl2 modifying factor
BPIFA1 BPI fold containing family A, member 1
BRD2 bromodomain containing 2
BST1 bone marrow stromal cell antigen 1
BTK Bruton agammaglobulinemia tyrosine kinase
BTLA B and T lymphocyte associated
C1QBP complement component 1, q subcomponent binding protein
C1QTNF3 C1q and tumor necrosis factor related protein 3
C3 complement component 3
C3AR1 complement component 3a receptor 1
C5AR1 complement component 5a receptor 1
CABIN1 calcineurin binding protein 1
CACNB3 calcium channel, voltage-dependent, beta 3 subunit
CACNB4 calcium channel, voltage-dependent, beta 4 subunit
CADM1 cell adhesion molecule 1
CARD11 caspase recruitment domain family, member 11
CARD9 caspase recruitment domain family, member 9
CASP12 caspase 12 (gene/pseudogene)
CASP4 caspase 4, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CBS cystathionine-beta-synthase
CC2D1A coiled-coil and C2 domain containing 1A
CCAR2 cell cycle and apoptosis regulator 2
CCDC171 coiled-coil domain containing 171
CCL13 chemokine (C-C motif) ligand 13
CCL5 chemokine (C-C motif) ligand 5
CCR1 chemokine (C-C motif) receptor 1
CCR10 chemokine (C-C motif) receptor 10
CCR2 chemokine (C-C motif) receptor 2
CCR3 chemokine (C-C motif) receptor 3
CCR4 chemokine (C-C motif) receptor 4
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCR6 chemokine (C-C motif) receptor 6
CCR7 chemokine (C-C motif) receptor 7
CCRL2 chemokine (C-C motif) receptor-like 2
CD14 CD14 molecule
CD180 CD180 molecule
CD19 CD19 molecule
CD1D CD1d molecule
CD200 CD200 molecule
CD200R1 CD200 receptor 1
CD22 CD22 molecule
CD247 CD247 molecule
CD274 CD274 molecule
CD276 CD276 molecule
CD28 CD28 molecule
CD300A CD300a molecule
CD300LF CD300 molecule-like family member f
CD36 CD36 molecule (thrombospondin receptor)
CD37 CD37 molecule
CD4 CD4 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CD44 CD44 molecule (Indian blood group)
CD47 CD47 molecule
CD69 CD69 molecule
CD7 CD7 molecule
CD72 CD72 molecule
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CD79A CD79a molecule, immunoglobulin-associated alpha
CD79B CD79b molecule, immunoglobulin-associated beta
CD80 CD80 molecule
CD81 CD81 molecule
CD83 CD83 molecule
CD84 CD84 molecule
CD86 CD86 molecule
CDH17 cadherin 17, LI cadherin (liver-intestine)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CH25H cholesterol 25-hydroxylase
CHD7 chromodomain helicase DNA binding protein 7
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal)
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CIITA class II, major histocompatibility complex, transactivator
CISH cytokine inducible SH2-containing protein
CLCA1 chloride channel accessory 1
CLEC10A C-type lectin domain family 10, member A
CLEC4D C-type lectin domain family 4, member D
CLEC4E C-type lectin domain family 4, member E
CLEC4F C-type lectin domain family 4, member F
CLEC6A C-type lectin domain family 6, member A
CLEC7A C-type lectin domain family 7, member A
CLIC4 chloride intracellular channel 4
CLK1 CDC-like kinase 1
CLNK cytokine-dependent hematopoietic cell linker
CLUAP1 clusterin associated protein 1
CNPY3 canopy FGF signaling regulator 3
COMMD3-BMI1 COMMD3-BMI1 readthrough
COMT catechol-O-methyltransferase
CORO1A coronin, actin binding protein, 1A
CPB2 carboxypeptidase B2 (plasma)
CR2 complement component (3d/Epstein Barr virus) receptor 2
CREB3L3 cAMP responsive element binding protein 3-like 3
CREBBP CREB binding protein
CRH corticotropin releasing hormone
CRLF2 cytokine receptor-like factor 2
CRP C-reactive protein, pentraxin-related
CRTAM cytotoxic and regulatory T cell molecule
CSF1R colony stimulating factor 1 receptor
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTSC cathepsin C
CTSE cathepsin E
CTSS cathepsin S
CUX1 cut-like homeobox 1
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL16 chemokine (C-X-C motif) ligand 16
CXCL6 chemokine (C-X-C motif) ligand 6
CXCL9 chemokine (C-X-C motif) ligand 9
CXCR2 chemokine (C-X-C motif) receptor 2
CXCR3 chemokine (C-X-C motif) receptor 3
CXCR4 chemokine (C-X-C motif) receptor 4
CYLD cylindromatosis (turban tumor syndrome)
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DBNL drebrin-like
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DGKA diacylglycerol kinase, alpha 80kDa
DGKZ diacylglycerol kinase, zeta
DHRS4 dehydrogenase/reductase (SDR family) member 4
DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58
DKK3 dickkopf WNT signaling pathway inhibitor 3
DLK1 delta-like 1 homolog (Drosophila)
DLL1 delta-like 1 (Drosophila)
DMD dystrophin
DOCK2 dedicator of cytokinesis 2
DOCK8 dedicator of cytokinesis 8
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DRD2 dopamine receptor D2
DSG3 desmoglein 3
DSG4 desmoglein 4
DTX1 deltex 1, E3 ubiquitin ligase
DUSP1 dual specificity phosphatase 1
DUSP10 dual specificity phosphatase 10
DUSP2 dual specificity phosphatase 2
DUSP4 dual specificity phosphatase 4
E2F1 E2F transcription factor 1
EBF1 early B-cell factor 1
EBI3 Epstein-Barr virus induced 3
ECM1 extracellular matrix protein 1
EFS embryonal Fyn-associated substrate
EGR1 early growth response 1
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EPHB6 EPH receptor B6
ERAP1 endoplasmic reticulum aminopeptidase 1
ESR1 estrogen receptor 1
F2R coagulation factor II (thrombin) receptor
F2RL1 coagulation factor II (thrombin) receptor-like 1
F3 coagulation factor III (thromboplastin, tissue factor)
FADS1 fatty acid desaturase 1
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FASTK Fas-activated serine/threonine kinase
FBN1 fibrillin 1
FBXO11 F-box protein 11
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23)
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FCMR Fc fragment of IgM receptor
FCRLA Fc receptor-like A
FCRLB Fc receptor-like B
FFAR2 free fatty acid receptor 2
FGA fibrinogen alpha chain
FGG fibrinogen gamma chain
FGR FGR proto-oncogene, Src family tyrosine kinase
FKBP11 FK506 binding protein 11, 19 kDa
FLG filaggrin
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FLT3 fms-related tyrosine kinase 3
FLT3LG fms-related tyrosine kinase 3 ligand
FNIP1 folliculin interacting protein 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXN1 forkhead box N1
FOXO1 forkhead box O1
FOXP3 forkhead box P3
FPR2 formyl peptide receptor 2
FUS FUS RNA binding protein
FYB FYN binding protein
FYN FYN proto-oncogene, Src family tyrosine kinase
G6PC2 glucose-6-phosphatase, catalytic, 2
GABPB2 GA binding protein transcription factor, beta subunit 2
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
GADD45G growth arrest and DNA-damage-inducible, gamma
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1
GAP43 growth associated protein 43
GAPT GRB2-binding adaptor protein, transmembrane
GATA1 GATA binding protein 1 (globin transcription factor 1)
GATA3 GATA binding protein 3
GBP5 guanylate binding protein 5
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type
GFI1 growth factor independent 1 transcription repressor
GIMAP1-GIMAP5 GIMAP1-GIMAP5 readthrough
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GON4L gon-4-like (C. elegans)
GPR132 G protein-coupled receptor 132
GPR15 G protein-coupled receptor 15
GPR183 G protein-coupled receptor 183
GPR21 G protein-coupled receptor 21
GPR34 G protein-coupled receptor 34
GPR65 G protein-coupled receptor 65
GPR84 G protein-coupled receptor 84
GRN granulin
H2AFX H2A histone family, member X
HAVCR1 hepatitis A virus cellular receptor 1
HAVCR2 hepatitis A virus cellular receptor 2
HAX1 HCLS1 associated protein X-1
HCK HCK proto-oncogene, Src family tyrosine kinase
HCST hematopoietic cell signal transducer
HDAC6 histone deacetylase 6
HEXB hexosaminidase B (beta polypeptide)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HLA-DMA major histocompatibility complex, class II, DM alpha
HLA-DOA major histocompatibility complex, class II, DO alpha
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-G major histocompatibility complex, class I, G
HMGN5 high mobility group nucleosome binding domain 5
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HOXC4 homeobox C4
HPGDS hematopoietic prostaglandin D synthase
HR hair growth associated
HRG histidine-rich glycoprotein
HRH1 histamine receptor H1
HRH4 histamine receptor H4
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
HSF1 heat shock transcription factor 1
HSH2D hematopoietic SH2 domain containing
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA1B heat shock 70kDa protein 1B
HSPB1 heat shock 27kDa protein 1
HSPB8 heat shock 22kDa protein 8
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
HTRA2 HtrA serine peptidase 2
ICAM1 intercellular adhesion molecule 1
ICOS inducible T-cell co-stimulator
ICOSLG inducible T-cell co-stimulator ligand
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IDO1 indoleamine 2,3-dioxygenase 1
IDO2 indoleamine 2,3-dioxygenase 2
IER3 immediate early response 3
IFIH1 interferon induced with helicase C domain 1
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFITM1 interferon induced transmembrane protein 1
IFNAR1 interferon (alpha, beta and omega) receptor 1
IFNAR2 interferon (alpha, beta and omega) receptor 2
IFNB1 interferon, beta 1, fibroblast
IFNG interferon, gamma
IFNGR1 interferon gamma receptor 1
IGHD immunoglobulin heavy constant delta
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IGHM immunoglobulin heavy constant mu
IGKC immunoglobulin kappa constant
IGLL1 immunoglobulin lambda-like polypeptide 1
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IKZF3 IKAROS family zinc finger 3 (Aiolos)
IL10 interleukin 10
IL10RA interleukin 10 receptor, alpha
IL10RB interleukin 10 receptor, beta
IL12A interleukin 12A
IL12B interleukin 12B
IL12RB1 interleukin 12 receptor, beta 1
IL12RB2 interleukin 12 receptor, beta 2
IL13 interleukin 13
IL13RA1 interleukin 13 receptor, alpha 1
IL13RA2 interleukin 13 receptor, alpha 2
IL15 interleukin 15
IL15RA interleukin 15 receptor, alpha
IL17A interleukin 17A
IL17C interleukin 17C
IL17F interleukin 17F
IL17RA interleukin 17 receptor A
IL17RB interleukin 17 receptor B
IL17RC interleukin 17 receptor C
IL18 interleukin 18
IL18R1 interleukin 18 receptor 1
IL18RAP interleukin 18 receptor accessory protein
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1R1 interleukin 1 receptor, type I
IL1RAP interleukin 1 receptor accessory protein
IL1RL1 interleukin 1 receptor-like 1
IL1RL2 interleukin 1 receptor-like 2
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
IL20RB interleukin 20 receptor beta
IL21 interleukin 21
IL21R interleukin 21 receptor
IL22 interleukin 22
IL23A interleukin 23, alpha subunit p19
IL23R interleukin 23 receptor
IL25 interleukin 25
IL27 interleukin 27
IL27RA interleukin 27 receptor, alpha
IL2RA interleukin 2 receptor, alpha
IL2RB interleukin 2 receptor, beta
IL2RG interleukin 2 receptor, gamma
IL31RA interleukin 31 receptor A
IL33 interleukin 33
IL34 interleukin 34
IL4 interleukin 4
IL4R interleukin 4 receptor
IL5 interleukin 5
IL5RA interleukin 5 receptor, alpha
IL6 interleukin 6
IL6R interleukin 6 receptor
IL6ST interleukin 6 signal transducer
IL9 interleukin 9
INCA1 inhibitor of CDK, cyclin A1 interacting protein 1
ING4 inhibitor of growth family, member 4
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
IRAK1 interleukin-1 receptor-associated kinase 1
IRAK2 interleukin-1 receptor-associated kinase 2
IRAK3 interleukin-1 receptor-associated kinase 3
IRAK4 interleukin-1 receptor-associated kinase 4
IRF1 interferon regulatory factor 1
IRF2 interferon regulatory factor 2
IRF3 interferon regulatory factor 3
IRF4 interferon regulatory factor 4
IRF5 interferon regulatory factor 5
IRF7 interferon regulatory factor 7
IRF8 interferon regulatory factor 8
IRF9 interferon regulatory factor 9
ITFG2 integrin alpha FG-GAP repeat containing 2
ITGAD integrin, alpha D
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITK IL2-inducible T-cell kinase
ITPKB inositol-trisphosphate 3-kinase B
JAK1 Janus kinase 1
JAK3 Janus kinase 3
JCHAIN joining chain of multimeric IgA and IgM
KDM8 lysine (K)-specific demethylase 8
KHSRP KH-type splicing regulatory protein
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLRK1 killer cell lectin-like receptor subfamily K, member 1
KRT1 keratin 1, type II
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LAMA2 laminin, alpha 2
LAPTM5 lysosomal protein transmembrane 5
LAT linker for activation of T cells
LAT2 linker for activation of T cells family, member 2
LAX1 lymphocyte transmembrane adaptor 1
LBP lipopolysaccharide binding protein
LCK LCK proto-oncogene, Src family tyrosine kinase
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
LDLR low density lipoprotein receptor
LECT2 leukocyte cell-derived chemotaxin 2
LEP leptin
LEPR leptin receptor
LGALS1 lectin, galactoside-binding, soluble, 1
LGALS3 lectin, galactoside-binding, soluble, 3
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LGMN legumain
LIF leukemia inhibitory factor
LIG4 ligase IV, DNA, ATP-dependent
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
LITAF lipopolysaccharide-induced TNF factor
LPAR2 lysophosphatidic acid receptor 2
LRRC4C leucine rich repeat containing 4C
LTA lymphotoxin alpha
LTB lymphotoxin beta (TNF superfamily, member 3)
LTB4R leukotriene B4 receptor
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3)
LY86 lymphocyte antigen 86
LY9 lymphocyte antigen 9
LY96 lymphocyte antigen 96
LYN LYN proto-oncogene, Src family tyrosine kinase
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAGED1 melanoma antigen family D1
MALT1 MALT1 paracaspase
MAN2A1 mannosidase, alpha, class 2A, member 1
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAP3K4 mitogen-activated protein kinase kinase kinase 4
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MARCH1 membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
MARCH7 membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase
MARCO macrophage receptor with collagenous structure
MARK2 MAP/microtubule affinity-regulating kinase 2
MAVS mitochondrial antiviral signaling protein
MB21D1 Mab-21 domain containing 1
MBP myelin basic protein
MBTPS1 membrane-bound transcription factor peptidase, site 1
MC4R melanocortin 4 receptor
MCAM melanoma cell adhesion molecule
MEFV Mediterranean fever
MEP1A meprin A, alpha (PABA peptide hydrolase)
MERTK MER proto-oncogene, tyrosine kinase
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MINA MYC induced nuclear antigen
MIR122 microRNA 122
MIR150 microRNA 150
MIR155 microRNA 155
MMP1 matrix metallopeptidase 1
MMP19 matrix metallopeptidase 19
MMP28 matrix metallopeptidase 28
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
MOG myelin oligodendrocyte glycoprotein
MPL MPL proto-oncogene, thrombopoietin receptor
MPZ myelin protein zero
MS4A2 membrane-spanning 4-domains, subfamily A, member 2
MSH2 mutS homolog 2
MSR1 macrophage scavenger receptor 1
MST1R macrophage stimulating 1 receptor
MSTN myostatin
MTA2 metastasis associated 1 family, member 2
MTA3 metastasis associated 1 family, member 3
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUC2 mucin 2, oligomeric mucus/gel-forming
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MUC5B mucin 5B, oligomeric mucus/gel-forming
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MYD88 myeloid differentiation primary response 88
MYO1G myosin IG
MYO6 myosin VI
MYSM1 Myb-like, SWIRM and MPN domains 1
NAMPT nicotinamide phosphoribosyltransferase
NCKAP1L NCK-associated protein 1-like
NCOA3 nuclear receptor coactivator 3
NDFIP1 Nedd4 family interacting protein 1
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NFATC2IP nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein
NFE2L2 nuclear factor, erythroid 2-like 2
NFIL3 nuclear factor, interleukin 3 regulated
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NFKBID nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
NGFR nerve growth factor receptor
NHEJ1 nonhomologous end-joining factor 1
NIPAL3 NIPA-like domain containing 3
NLRC3 NLR family, CARD domain containing 3
NLRC4 NLR family, CARD domain containing 4
NLRC5 NLR family, CARD domain containing 5
NLRP1 NLR family, pyrin domain containing 1
NLRP10 NLR family, pyrin domain containing 10
NLRP12 NLR family, pyrin domain containing 12
NLRP3 NLR family, pyrin domain containing 3
NLRP6 NLR family, pyrin domain containing 6
NLRX1 NLR family member X1
NME2 NME/NM23 nucleoside diphosphate kinase 2
NMU neuromedin U
NOD1 nucleotide-binding oligomerization domain containing 1
NOD2 nucleotide-binding oligomerization domain containing 2
NOS2 nitric oxide synthase 2, inducible
NPY1R neuropeptide Y receptor Y1
NUP98 nucleoporin 98kDa
OASL 2'-5'-oligoadenylate synthetase-like
OLFM4 olfactomedin 4
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
ORAI1 ORAI calcium release-activated calcium modulator 1
OSMR oncostatin M receptor
OTUD7B OTU deubiquitinase 7B
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PACSIN1 protein kinase C and casein kinase substrate in neurons 1
PARG poly (ADP-ribose) glycohydrolase
PARP1 poly (ADP-ribose) polymerase 1
PARP14 poly (ADP-ribose) polymerase family, member 14
PAX5 paired box 5
PBK PDZ binding kinase
PCSK1 proprotein convertase subtilisin/kexin type 1
PDCD1 programmed cell death 1
PDCD1LG2 programmed cell death 1 ligand 2
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDE4B phosphodiesterase 4B, cAMP-specific
PDE4D phosphodiesterase 4D, cAMP-specific
PDLIM2 PDZ and LIM domain 2 (mystique)
PECAM1 platelet/endothelial cell adhesion molecule 1
PELI1 pellino E3 ubiquitin protein ligase 1
PGLYRP1 peptidoglycan recognition protein 1
PGLYRP2 peptidoglycan recognition protein 2
PGLYRP3 peptidoglycan recognition protein 3
PGLYRP4 peptidoglycan recognition protein 4
PGR progesterone receptor
PIGR polymeric immunoglobulin receptor
PIK3AP1 phosphoinositide-3-kinase adaptor protein 1
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PILRB paired immunoglobin-like type 2 receptor beta
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PINK1 PTEN induced putative kinase 1
PITX3 paired-like homeodomain 3
PKN1 protein kinase N1
PLA2G10 phospholipase A2, group X
PLA2G2D phospholipase A2, group IID
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLAT plasminogen activator, tissue
PLAU plasminogen activator, urokinase
PLAUR plasminogen activator, urokinase receptor
PLCD1 phospholipase C, delta 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLCL2 phospholipase C-like 2
PLG plasminogen
POLB polymerase (DNA directed), beta
POLQ polymerase (DNA directed), theta
POMC proopiomelanocortin
POMT1 protein-O-mannosyltransferase 1
POU2AF1 POU class 2 associating factor 1
POU2F2 POU class 2 homeobox 2
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPIA peptidylprolyl isomerase A (cyclophilin A)
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme
PPT1 palmitoyl-protein thioesterase 1
PRAP1 proline-rich acidic protein 1
PRF1 perforin 1 (pore forming protein)
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PRKCB protein kinase C, beta
PRKCD protein kinase C, delta
PRKCE protein kinase C, epsilon
PRKCQ protein kinase C, theta
PRKD2 protein kinase D2
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRMT8 protein arginine methyltransferase 8
PRPSAP2 phosphoribosyl pyrophosphate synthetase-associated protein 2
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
PTGDR2 prostaglandin D2 receptor 2
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTPRC protein tyrosine phosphatase, receptor type, C
PTTG1 pituitary tumor-transforming 1
PVR poliovirus receptor
PYCARD PYD and CARD domain containing
RAB27A RAB27A, member RAS oncogene family
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1
RAD50 RAD50 homolog (S. cerevisiae)
RAG1 recombination activating gene 1
RAG2 recombination activating gene 2
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RAP1A RAP1A, member of RAS oncogene family
RASGRF2 Ras protein-specific guanine nucleotide-releasing factor 2
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated)
RASSF5 Ras association (RalGDS/AF-6) domain family member 5
RBPJ recombination signal binding protein for immunoglobulin kappa J region
RC3H1 ring finger and CCCH-type domains 1
RC3H2 ring finger and CCCH-type domains 2
RCAN1 regulator of calcineurin 1
REG3G regenerating islet-derived 3 gamma
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RETNLB resistin like beta
RFTN1 raftlin, lipid raft linker 1
RFX5 regulatory factor X, 5 (influences HLA class II expression)
RGS1 regulator of G-protein signaling 1
RGS13 regulator of G-protein signaling 13
RGS16 regulator of G-protein signaling 16
RHBDD3 rhomboid domain containing 3
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RHOG ras homolog family member G
RIF1 replication timing regulatory factor 1
RIPK2 receptor-interacting serine-threonine kinase 2
RLTPR RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
RNF168 ring finger protein 168, E3 ubiquitin protein ligase
RNF19B ring finger protein 19B
RNF8 ring finger protein 8, E3 ubiquitin protein ligase
RORA RAR-related orphan receptor A
RORC RAR-related orphan receptor C
RSAD2 radical S-adenosyl methionine domain containing 2
RUNX3 runt-related transcription factor 3
RUVBL2 RuvB-like AAA ATPase 2
S100A9 S100 calcium binding protein A9
S1PR3 sphingosine-1-phosphate receptor 3
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SARM1 sterile alpha and TIR motif containing 1
SASH3 SAM and SH3 domain containing 3
SCARB1 scavenger receptor class B, member 1
SCARF1 scavenger receptor class F, member 1
SCTR secretin receptor
SDC1 syndecan 1
SELK selenoprotein K
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SELPLG selectin P ligand
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SFN stratifin
SFTPA1 surfactant protein A1
SFTPD surfactant protein D
SH2B2 SH2B adaptor protein 2
SH2D1A SH2 domain containing 1A
SH2D1B SH2 domain containing 1B
SH2D2A SH2 domain containing 2A
SH2D3C SH2 domain containing 3C
SH3BP2 SH3-domain binding protein 2
SHARPIN SHANK-associated RH domain interactor
SIAE sialic acid acetylesterase
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin
SIGLEC10 sialic acid binding Ig-like lectin 10
SIRT1 sirtuin 1
SIRT3 sirtuin 3
SIRT7 sirtuin 7
SIT1 signaling threshold regulating transmembrane adaptor 1
SKAP1 src kinase associated phosphoprotein 1
SKAP2 src kinase associated phosphoprotein 2
SLAMF1 signaling lymphocytic activation molecule family member 1
SLAMF6 SLAM family member 6
SLC15A4 solute carrier family 15 (oligopeptide transporter), member 4
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4
SLPI secretory leukocyte peptidase inhibitor
SMAD3 SMAD family member 3
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SNX5 sorting nexin 5
SOCS1 suppressor of cytokine signaling 1
SOCS2 suppressor of cytokine signaling 2
SOCS3 suppressor of cytokine signaling 3
SOD3 superoxide dismutase 3, extracellular
SORT1 sortilin 1
SPHK1 sphingosine kinase 1
SPI1 Spi-1 proto-oncogene
SPIB Spi-B transcription factor (Spi-1/PU.1 related)
SPNS2 spinster homolog 2 (Drosophila)
SPON2 spondin 2, extracellular matrix protein
SPP1 secreted phosphoprotein 1
SPPL2A signal peptide peptidase like 2A
SPRED1 sprouty-related, EVH1 domain containing 1
SPTA1 spectrin, alpha, erythrocytic 1
SQSTM1 sequestosome 1
SRA1 steroid receptor RNA activator 1
SSTR4 somatostatin receptor 4
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT4 signal transducer and activator of transcription 4
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
STIM1 stromal interaction molecule 1
STK17B serine/threonine kinase 17b
STK4 serine/threonine kinase 4
STX11 syntaxin 11
SUCNR1 succinate receptor 1
SWAP70 SWAP switching B-cell complex 70kDa subunit
SYK spleen tyrosine kinase
SYTL1 synaptotagmin-like 1
TANK TRAF family member-associated NFKB activator
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1
TBC1D10C TBC1 domain family, member 10C
TBC1D23 TBC1 domain family, member 23
TBK1 TANK-binding kinase 1
TBX21 T-box 21
TBXA2R thromboxane A2 receptor
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
TESPA1 thymocyte expressed, positive selection associated 1
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFB1 transforming growth factor, beta 1
TGIF1 TGFB-induced factor homeobox 1
THBD thrombomodulin
THBS1 thrombospondin 1
TICAM1 toll-like receptor adaptor molecule 1
TICAM2 toll-like receptor adaptor molecule 2
TIGIT T cell immunoreceptor with Ig and ITIM domains
TIMD4 T-cell immunoglobulin and mucin domain containing 4
TIMP3 TIMP metallopeptidase inhibitor 3
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein
TLR1 toll-like receptor 1
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TLR5 toll-like receptor 5
TLR6 toll-like receptor 6
TLR7 toll-like receptor 7
TLR8 toll-like receptor 8
TLR9 toll-like receptor 9
TMEM173 transmembrane protein 173
TMEM79 transmembrane protein 79
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFAIP8L2 tumor necrosis factor, alpha-induced protein 8-like 2
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TNFRSF18 tumor necrosis factor receptor superfamily, member 18
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TNIP1 TNFAIP3 interacting protein 1
TOLLIP toll interacting protein
TP53 tumor protein p53
TRADD TNFRSF1A-associated via death domain
TRAF2 TNF receptor-associated factor 2
TRAF3IP2 TRAF3 interacting protein 2
TRAF5 TNF receptor-associated factor 5
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRAFD1 TRAF-type zinc finger domain containing 1
TREM2 triggering receptor expressed on myeloid cells 2
TREML1 triggering receptor expressed on myeloid cells-like 1
TREX1 three prime repair exonuclease 1
TRIB1 tribbles pseudokinase 1
TRIM21 tripartite motif containing 21
TRIM27 tripartite motif containing 27
TRIP10 thyroid hormone receptor interactor 10
TROVE2 TROVE domain family, member 2
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSC22D3 TSC22 domain family, member 3
TSLP thymic stromal lymphopoietin
TUSC2 tumor suppressor candidate 2
TWIST2 twist family bHLH transcription factor 2
TXK TXK tyrosine kinase
TXNDC2 thioredoxin domain containing 2 (spermatozoa)
TYK2 tyrosine kinase 2
TYROBP TYRO protein tyrosine kinase binding protein
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats
UNC13D unc-13 homolog D (C. elegans)
UNC93B1 unc-93 homolog B1 (C. elegans)
UNG uracil-DNA glycosylase
USP18 ubiquitin specific peptidase 18
USP21 ubiquitin specific peptidase 21
USP25 ubiquitin specific peptidase 25
UXS1 UDP-glucuronate decarboxylase 1
VAV1 vav 1 guanine nucleotide exchange factor
VAV2 vav 2 guanine nucleotide exchange factor
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VIPR2 vasoactive intestinal peptide receptor 2
VTCN1 V-set domain containing T cell activation inhibitor 1
WAS Wiskott-Aldrich syndrome
WIPF1 WAS/WASL interacting protein family, member 1
XCR1 chemokine (C motif) receptor 1
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZBTB32 zinc finger and BTB domain containing 32
ZBTB7B zinc finger and BTB domain containing 7B
ZC3H12A zinc finger CCCH-type containing 12A
ZC3H12D zinc finger CCCH-type containing 12D
ZEB1 zinc finger E-box binding homeobox 1
ZFPM1 zinc finger protein, FOG family member 1
ZNF318 zinc finger protein 318