abnormal hypersensitivity reaction Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description immune response that results in tissue injury (Mammalian Phenotype Ontology, MP_0002148)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0002148
Similar Terms
Downloads & Tools

Genes

151 gene mutations causing the abnormal hypersensitivity reaction phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ADORA2B adenosine A2b receptor
AHR aryl hydrocarbon receptor
ALOX5 arachidonate 5-lipoxygenase
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ANXA5 annexin A5
APOE apolipoprotein E
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
C3AR1 complement component 3a receptor 1
CCL13 chemokine (C-C motif) ligand 13
CCL17 chemokine (C-C motif) ligand 17
CCL3L3 chemokine (C-C motif) ligand 3-like 3
CCL5 chemokine (C-C motif) ligand 5
CCR1 chemokine (C-C motif) receptor 1
CCR2 chemokine (C-C motif) receptor 2
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCR6 chemokine (C-C motif) receptor 6
CCR7 chemokine (C-C motif) receptor 7
CCRL2 chemokine (C-C motif) receptor-like 2
CD207 CD207 molecule, langerin
CD28 CD28 molecule
CD300LF CD300 molecule-like family member f
CD40 CD40 molecule, TNF receptor superfamily member 5
CD44 CD44 molecule (Indian blood group)
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CD81 CD81 molecule
CD83 CD83 molecule
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CFH complement factor H
CISH cytokine inducible SH2-containing protein
CLEC4D C-type lectin domain family 4, member D
CLEC4E C-type lectin domain family 4, member E
CPA3 carboxypeptidase A3 (mast cell)
CXCL10 chemokine (C-X-C motif) ligand 10
CYSLTR1 cysteinyl leukotriene receptor 1
CYSLTR2 cysteinyl leukotriene receptor 2
DUSP1 dual specificity phosphatase 1
DUSP10 dual specificity phosphatase 10
ECM1 extracellular matrix protein 1
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EPHB6 EPH receptor B6
F11R F11 receptor
F2RL1 coagulation factor II (thrombin) receptor-like 1
FAS Fas cell surface death receptor
FBN1 fibrillin 1
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23)
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FLG filaggrin
FOXP3 forkhead box P3
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
FYN FYN proto-oncogene, Src family tyrosine kinase
GAB2 GRB2-associated binding protein 2
GADD45G growth arrest and DNA-damage-inducible, gamma
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GPR34 G protein-coupled receptor 34
HLA-DMA major histocompatibility complex, class II, DM alpha
HPGDS hematopoietic prostaglandin D synthase
ICAM1 intercellular adhesion molecule 1
IDO1 indoleamine 2,3-dioxygenase 1
IDO2 indoleamine 2,3-dioxygenase 2
IFNG interferon, gamma
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1)
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IGHM immunoglobulin heavy constant mu
IKZF3 IKAROS family zinc finger 3 (Aiolos)
IL10 interleukin 10
IL12A interleukin 12A
IL12B interleukin 12B
IL13 interleukin 13
IL15 interleukin 15
IL17A interleukin 17A
IL1B interleukin 1, beta
IL1R1 interleukin 1 receptor, type I
IL20RB interleukin 20 receptor beta
IL21R interleukin 21 receptor
IL25 interleukin 25
IL27 interleukin 27
IL3 interleukin 3
IL34 interleukin 34
IL4R interleukin 4 receptor
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
LAPTM5 lysosomal protein transmembrane 5
LBP lipopolysaccharide binding protein
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
LPAR2 lysophosphatidic acid receptor 2
LTA4H leukotriene A4 hydrolase
LTB4R leukotriene B4 receptor
LTB4R2 leukotriene B4 receptor 2
LTC4S leukotriene C4 synthase
MILR1 mast cell immunoglobulin-like receptor 1
MME membrane metallo-endopeptidase
MMP19 matrix metallopeptidase 19
MMP3 matrix metallopeptidase 3
MMP9 matrix metallopeptidase 9
MS4A2 membrane-spanning 4-domains, subfamily A, member 2
MST1R macrophage stimulating 1 receptor
NLRP12 NLR family, pyrin domain containing 12
NLRP3 NLR family, pyrin domain containing 3
NPY1R neuropeptide Y receptor Y1
ORAI1 ORAI calcium release-activated calcium modulator 1
PGF placental growth factor
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta
PLA2G2D phospholipase A2, group IID
PLA2G3 phospholipase A2, group III
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PPIA peptidylprolyl isomerase A (cyclophilin A)
PTAFR platelet-activating factor receptor
PTGDR prostaglandin D2 receptor (DP)
PTGDR2 prostaglandin D2 receptor 2
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTGES prostaglandin E synthase
PTGES2 prostaglandin E synthase 2
PTPRC protein tyrosine phosphatase, receptor type, C
PYCARD PYD and CARD domain containing
RAG2 recombination activating gene 2
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RGS13 regulator of G-protein signaling 13
RGS3 regulator of G-protein signaling 3
RHOH ras homolog family member H
SELE selectin E
SELL selectin L
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4
SPP1 secreted phosphoprotein 1
SSTR4 somatostatin receptor 4
STIM1 stromal interaction molecule 1
STXBP2 syntaxin binding protein 2
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1
TBXA2R thromboxane A2 receptor
TICAM1 toll-like receptor adaptor molecule 1
TNF tumor necrosis factor
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF4 tumor necrosis factor receptor superfamily, member 4
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TRIP10 thyroid hormone receptor interactor 10
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TRPM7 transient receptor potential cation channel, subfamily M, member 7
TSC22D3 TSC22 domain family, member 3
TYROBP TYRO protein tyrosine kinase binding protein
VAMP8 vesicle-associated membrane protein 8
VIPR2 vasoactive intestinal peptide receptor 2