abnormal humoral immune response Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any functional anomaly of the aspect of immunity that is mediated by secreted antibodies produced in the cells of the B lymphocyte lineage (B cell) and the accessory processes that accompany it, including Th2 activation and cytokine production, germinal center formation and isotype switching, affinity maturation and memory cell generation; it also refers to the effector functions of antibody, which include pathogen and toxin neutralization, classical complement activation, and opsonin promotion of phagocytosis and pathogen elimination (Mammalian Phenotype Ontology, MP_0001800)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0001800
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Genes

446 gene mutations causing the abnormal humoral immune response phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ACSL3 acyl-CoA synthetase long-chain family member 3
ADCY9 adenylate cyclase 9
AICDA activation-induced cytidine deaminase
AKAP13 A kinase (PRKA) anchor protein 13
AMPD3 adenosine monophosphate deaminase 3
AOAH acyloxyacyl hydrolase (neutrophil)
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
APOE apolipoprotein E
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATF3 activating transcription factor 3
ATM ATM serine/threonine kinase
ATP11C ATPase, class VI, type 11C
AVPR1A arginine vasopressin receptor 1A
B2M beta-2-microglobulin
B3GNT5 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
BANK1 B-cell scaffold protein with ankyrin repeats 1
BATF basic leucine zipper transcription factor, ATF-like
BBS4 Bardet-Biedl syndrome 4
BBX bobby sox homolog (Drosophila)
BCL10 B-cell CLL/lymphoma 10
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BCL3 B-cell CLL/lymphoma 3
BCL6 B-cell CLL/lymphoma 6
BHLHE40 basic helix-loop-helix family, member e40
BIRC3 baculoviral IAP repeat containing 3
BLM Bloom syndrome, RecQ helicase-like
BLNK B-cell linker
BMF Bcl2 modifying factor
BST1 bone marrow stromal cell antigen 1
BTK Bruton agammaglobulinemia tyrosine kinase
BTLA B and T lymphocyte associated
C1QBP complement component 1, q subcomponent binding protein
C1QTNF3 C1q and tumor necrosis factor related protein 3
C3 complement component 3
C3AR1 complement component 3a receptor 1
C4A complement component 4A (Rodgers blood group)
C5AR1 complement component 5a receptor 1
CABIN1 calcineurin binding protein 1
CACNB4 calcium channel, voltage-dependent, beta 4 subunit
CARD11 caspase recruitment domain family, member 11
CCDC171 coiled-coil domain containing 171
CCL13 chemokine (C-C motif) ligand 13
CCR1 chemokine (C-C motif) receptor 1
CCR10 chemokine (C-C motif) receptor 10
CCR2 chemokine (C-C motif) receptor 2
CCR4 chemokine (C-C motif) receptor 4
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCR6 chemokine (C-C motif) receptor 6
CCR7 chemokine (C-C motif) receptor 7
CD180 CD180 molecule
CD19 CD19 molecule
CD1D CD1d molecule
CD22 CD22 molecule
CD274 CD274 molecule
CD28 CD28 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD37 CD37 molecule
CD38 CD38 molecule
CD4 CD4 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD69 CD69 molecule
CD72 CD72 molecule
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CD79A CD79a molecule, immunoglobulin-associated alpha
CD79B CD79b molecule, immunoglobulin-associated beta
CD80 CD80 molecule
CD81 CD81 molecule
CD83 CD83 molecule
CD84 CD84 molecule
CD86 CD86 molecule
CDH17 cadherin 17, LI cadherin (liver-intestine)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CFB complement factor B
CFD complement factor D (adipsin)
CFH complement factor H
CFP complement factor properdin
CH25H cholesterol 25-hydroxylase
CHD7 chromodomain helicase DNA binding protein 7
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal)
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CIITA class II, major histocompatibility complex, transactivator
CLEC4D C-type lectin domain family 4, member D
CLEC4E C-type lectin domain family 4, member E
CLEC9A C-type lectin domain family 9, member A
CLK1 CDC-like kinase 1
CLUAP1 clusterin associated protein 1
COMMD3-BMI1 COMMD3-BMI1 readthrough
CPB2 carboxypeptidase B2 (plasma)
CPN1 carboxypeptidase N, polypeptide 1
CR2 complement component (3d/Epstein Barr virus) receptor 2
CRLF2 cytokine receptor-like factor 2
CTSE cathepsin E
CTSS cathepsin S
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL9 chemokine (C-X-C motif) ligand 9
CXCR2 chemokine (C-X-C motif) receptor 2
CXCR4 chemokine (C-X-C motif) receptor 4
CYLD cylindromatosis (turban tumor syndrome)
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DBNL drebrin-like
DCN decorin
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DHRS4 dehydrogenase/reductase (SDR family) member 4
DIAPH1 diaphanous-related formin 1
DKK3 dickkopf WNT signaling pathway inhibitor 3
DLK1 delta-like 1 homolog (Drosophila)
DLL1 delta-like 1 (Drosophila)
DOCK2 dedicator of cytokinesis 2
DOCK8 dedicator of cytokinesis 8
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DSG3 desmoglein 3
DSG4 desmoglein 4
DUSP4 dual specificity phosphatase 4
EBF1 early B-cell factor 1
ECM1 extracellular matrix protein 1
EFS embryonal Fyn-associated substrate
ESR1 estrogen receptor 1
F2RL1 coagulation factor II (thrombin) receptor-like 1
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23)
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FCMR Fc fragment of IgM receptor
FCRLA Fc receptor-like A
FCRLB Fc receptor-like B
FKBP11 FK506 binding protein 11, 19 kDa
FLG filaggrin
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FLT3LG fms-related tyrosine kinase 3 ligand
FNIP1 folliculin interacting protein 1
FOXN1 forkhead box N1
FOXP3 forkhead box P3
FPR2 formyl peptide receptor 2
FUS FUS RNA binding protein
FYN FYN proto-oncogene, Src family tyrosine kinase
GABPB2 GA binding protein transcription factor, beta subunit 2
GADD45A growth arrest and DNA-damage-inducible, alpha
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1
GAP43 growth associated protein 43
GAPT GRB2-binding adaptor protein, transmembrane
GATA3 GATA binding protein 3
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type
GIMAP1-GIMAP5 GIMAP1-GIMAP5 readthrough
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GON4L gon-4-like (C. elegans)
GPR132 G protein-coupled receptor 132
GPX7 glutathione peroxidase 7
H2AFX H2A histone family, member X
HAX1 HCLS1 associated protein X-1
HCLS1 hematopoietic cell-specific Lyn substrate 1
HDAC6 histone deacetylase 6
HEXB hexosaminidase B (beta polypeptide)
HLA-DOA major histocompatibility complex, class II, DO alpha
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HMGN5 high mobility group nucleosome binding domain 5
HOXC4 homeobox C4
HR hair growth associated
HRH1 histamine receptor H1
HRH4 histamine receptor H4
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
ICOS inducible T-cell co-stimulator
ICOSLG inducible T-cell co-stimulator ligand
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IFITM1 interferon induced transmembrane protein 1
IFNAR1 interferon (alpha, beta and omega) receptor 1
IFNAR2 interferon (alpha, beta and omega) receptor 2
IFNG interferon, gamma
IFNGR1 interferon gamma receptor 1
IGHD immunoglobulin heavy constant delta
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IGHM immunoglobulin heavy constant mu
IGKC immunoglobulin kappa constant
IGLL1 immunoglobulin lambda-like polypeptide 1
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IKZF3 IKAROS family zinc finger 3 (Aiolos)
IL10 interleukin 10
IL10RA interleukin 10 receptor, alpha
IL13 interleukin 13
IL13RA1 interleukin 13 receptor, alpha 1
IL13RA2 interleukin 13 receptor, alpha 2
IL15 interleukin 15
IL17A interleukin 17A
IL17F interleukin 17F
IL17RB interleukin 17 receptor B
IL1R1 interleukin 1 receptor, type I
IL1RL1 interleukin 1 receptor-like 1
IL2 interleukin 2
IL21 interleukin 21
IL21R interleukin 21 receptor
IL23A interleukin 23, alpha subunit p19
IL25 interleukin 25
IL2RA interleukin 2 receptor, alpha
IL2RB interleukin 2 receptor, beta
IL2RG interleukin 2 receptor, gamma
IL31RA interleukin 31 receptor A
IL33 interleukin 33
IL4 interleukin 4
IL4R interleukin 4 receptor
IL5 interleukin 5
IL5RA interleukin 5 receptor, alpha
IL6 interleukin 6
IL6ST interleukin 6 signal transducer
INCA1 inhibitor of CDK, cyclin A1 interacting protein 1
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
IRF1 interferon regulatory factor 1
IRF2 interferon regulatory factor 2
IRF4 interferon regulatory factor 4
IRF8 interferon regulatory factor 8
ITFG2 integrin alpha FG-GAP repeat containing 2
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITK IL2-inducible T-cell kinase
ITPKB inositol-trisphosphate 3-kinase B
JAK1 Janus kinase 1
JAK3 Janus kinase 3
JCHAIN joining chain of multimeric IgA and IgM
KDM8 lysine (K)-specific demethylase 8
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LAMA2 laminin, alpha 2
LAT linker for activation of T cells
LAX1 lymphocyte transmembrane adaptor 1
LCK LCK proto-oncogene, Src family tyrosine kinase
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
LGALS3 lectin, galactoside-binding, soluble, 3
LIG4 ligase IV, DNA, ATP-dependent
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
LPAR2 lysophosphatidic acid receptor 2
LTA lymphotoxin alpha
LTB lymphotoxin beta (TNF superfamily, member 3)
LTB4R leukotriene B4 receptor
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3)
LY86 lymphocyte antigen 86
LYN LYN proto-oncogene, Src family tyrosine kinase
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MALT1 MALT1 paracaspase
MAN2A1 mannosidase, alpha, class 2A, member 1
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5
MARK2 MAP/microtubule affinity-regulating kinase 2
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
MASP2 mannan-binding lectin serine peptidase 2
MAVS mitochondrial antiviral signaling protein
MINA MYC induced nuclear antigen
MIR150 microRNA 150
MIR155 microRNA 155
MMP9 matrix metallopeptidase 9
MSH2 mutS homolog 2
MTA3 metastasis associated 1 family, member 3
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MYD88 myeloid differentiation primary response 88
MYO6 myosin VI
MYSM1 Myb-like, SWIRM and MPN domains 1
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NFE2L2 nuclear factor, erythroid 2-like 2
NFIL3 nuclear factor, interleukin 3 regulated
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NFKBID nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
NHEJ1 nonhomologous end-joining factor 1
NIPAL3 NIPA-like domain containing 3
NLRP10 NLR family, pyrin domain containing 10
NLRP6 NLR family, pyrin domain containing 6
NOD2 nucleotide-binding oligomerization domain containing 2
NOS2 nitric oxide synthase 2, inducible
NPY1R neuropeptide Y receptor Y1
NUP98 nucleoporin 98kDa
OTUD7B OTU deubiquitinase 7B
PARP14 poly (ADP-ribose) polymerase family, member 14
PAX5 paired box 5
PDCD1 programmed cell death 1
PDCD1LG2 programmed cell death 1 ligand 2
PDE7A phosphodiesterase 7A
PIGR polymeric immunoglobulin receptor
PIK3AP1 phosphoinositide-3-kinase adaptor protein 1
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PITX3 paired-like homeodomain 3
PKN1 protein kinase N1
PLA2G10 phospholipase A2, group X
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLCL2 phospholipase C-like 2
POLB polymerase (DNA directed), beta
POLQ polymerase (DNA directed), theta
POMT1 protein-O-mannosyltransferase 1
POU2AF1 POU class 2 associating factor 1
POU2F2 POU class 2 homeobox 2
PPARG peroxisome proliferator-activated receptor gamma
PPIA peptidylprolyl isomerase A (cyclophilin A)
PRAP1 proline-rich acidic protein 1
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PRKCB protein kinase C, beta
PRKCD protein kinase C, delta
PRKD2 protein kinase D2
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRMT8 protein arginine methyltransferase 8
PRPSAP2 phosphoribosyl pyrophosphate synthetase-associated protein 2
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
PTGDR2 prostaglandin D2 receptor 2
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTPRC protein tyrosine phosphatase, receptor type, C
PTTG1 pituitary tumor-transforming 1
PVR poliovirus receptor
PYCARD PYD and CARD domain containing
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1
RAG1 recombination activating gene 1
RAG2 recombination activating gene 2
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated)
RASSF5 Ras association (RalGDS/AF-6) domain family member 5
RBPJ recombination signal binding protein for immunoglobulin kappa J region
RC3H1 ring finger and CCCH-type domains 1
RCAN1 regulator of calcineurin 1
REG3G regenerating islet-derived 3 gamma
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RETNLB resistin like beta
RFTN1 raftlin, lipid raft linker 1
RFX5 regulatory factor X, 5 (influences HLA class II expression)
RGS1 regulator of G-protein signaling 1
RGS13 regulator of G-protein signaling 13
RHOG ras homolog family member G
RIF1 replication timing regulatory factor 1
RIPK2 receptor-interacting serine-threonine kinase 2
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
RNF168 ring finger protein 168, E3 ubiquitin protein ligase
RNF8 ring finger protein 8, E3 ubiquitin protein ligase
RORA RAR-related orphan receptor A
RSAD2 radical S-adenosyl methionine domain containing 2
RUNX3 runt-related transcription factor 3
RUVBL2 RuvB-like AAA ATPase 2
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SASH3 SAM and SH3 domain containing 3
SCARF1 scavenger receptor class F, member 1
SDC1 syndecan 1
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SFN stratifin
SH2B2 SH2B adaptor protein 2
SH2D1A SH2 domain containing 1A
SH2D3C SH2 domain containing 3C
SH3BP2 SH3-domain binding protein 2
SHARPIN SHANK-associated RH domain interactor
SIAE sialic acid acetylesterase
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin
SIGLEC10 sialic acid binding Ig-like lectin 10
SIRT1 sirtuin 1
SKAP2 src kinase associated phosphoprotein 2
SNX5 sorting nexin 5
SPI1 Spi-1 proto-oncogene
SPIB Spi-B transcription factor (Spi-1/PU.1 related)
SPNS2 spinster homolog 2 (Drosophila)
SPPL2A signal peptide peptidase like 2A
SPTA1 spectrin, alpha, erythrocytic 1
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
SWAP70 SWAP switching B-cell complex 70kDa subunit
SYK spleen tyrosine kinase
SYTL1 synaptotagmin-like 1
TACR1 tachykinin receptor 1
TANK TRAF family member-associated NFKB activator
TBC1D10C TBC1 domain family, member 10C
TBK1 TANK-binding kinase 1
TBX21 T-box 21
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
THEMIS thymocyte selection associated
TICAM1 toll-like receptor adaptor molecule 1
TIMD4 T-cell immunoglobulin and mucin domain containing 4
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein
TLR1 toll-like receptor 1
TLR2 toll-like receptor 2
TLR7 toll-like receptor 7
TLR8 toll-like receptor 8
TMEM173 transmembrane protein 173
TMEM79 transmembrane protein 79
TNF tumor necrosis factor
TNFAIP8L2 tumor necrosis factor, alpha-induced protein 8-like 2
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TNIP1 TNFAIP3 interacting protein 1
TOM1L2 target of myb1-like 2 (chicken)
TRADD TNFRSF1A-associated via death domain
TRAF3 TNF receptor-associated factor 3
TRAF3IP2 TRAF3 interacting protein 2
TRAF5 TNF receptor-associated factor 5
TREX1 three prime repair exonuclease 1
TRIP10 thyroid hormone receptor interactor 10
TROVE2 TROVE domain family, member 2
TSLP thymic stromal lymphopoietin
TYK2 tyrosine kinase 2
TYROBP TYRO protein tyrosine kinase binding protein
UNC93B1 unc-93 homolog B1 (C. elegans)
UNG uracil-DNA glycosylase
UXS1 UDP-glucuronate decarboxylase 1
VAV1 vav 1 guanine nucleotide exchange factor
VAV2 vav 2 guanine nucleotide exchange factor
VIPR2 vasoactive intestinal peptide receptor 2
WAS Wiskott-Aldrich syndrome
WIPF1 WAS/WASL interacting protein family, member 1
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZBTB7B zinc finger and BTB domain containing 7B
ZC3H12A zinc finger CCCH-type containing 12A
ZEB1 zinc finger E-box binding homeobox 1
ZNF318 zinc finger protein 318