abnormal head mesenchyme morphology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any structural anomaly of the primordial embryonic connective tissue of the developing head, consisting of mesenchymal cells supported in interlaminar jelly, that derive mostly from the mesoderm and contribute to head connective tissue, bone and musculature in conjunction with cranial neural crest cells (Mammalian Phenotype Ontology, MP_0011260)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0011260
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27 gene mutations causing the abnormal head mesenchyme morphology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ALX3 ALX homeobox 3
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1
BMP4 bone morphogenetic protein 4
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1
FGFR1 fibroblast growth factor receptor 1
FN1 fibronectin 1
FUZ fuzzy planar cell polarity protein
GLMN glomulin, FKBP associated protein
HAS2 hyaluronan synthase 2
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIRA histone cell cycle regulator
KAT2A K(lysine) acetyltransferase 2A
MAPK7 mitogen-activated protein kinase 7
MED12 mediator complex subunit 12
MIXL1 Mix paired-like homeobox
OVOL2 ovo-like zinc finger 2
PMM2 phosphomannomutase 2
PRDM1 PR domain containing 1, with ZNF domain
PTK2 protein tyrosine kinase 2
RSPO2 R-spondin 2
SKI SKI proto-oncogene
SOX10 SRY (sex determining region Y)-box 10
STK11 serine/threonine kinase 11
TTN titin
VCL vinculin